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[The functional status and work capacity of coal mine workers with a history of an acute respiratory disease].

Acute respiratory diseases weaken bodily resistance to factors of industrial environment and activities. In subjects with vago- and normotonic type regulation, high level of adaptive capability permits the overstrain states to be avoided during the first post-illness days. The whole process of minimization of cost of the primary reaction of an organism gets completed by the end of the first week. In 80 percent of miners with sympathetic type vegetative dysbalance, industrial activities at week I are accompanied by a surplus vegetative maintenance. The process of readaptation to work gets protracted by 2 to 4 weeks, which fact attests to the need for such miners to be assigned to those jobs for which they are best suited and for dispensary health promotion in a mine's health-station setting.

Acute Disease↗

Clinical effectiveness of tulathromycin, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease.

The efficacy of tulathromycin in decreasing the incidence of morbidity and mortality due to bovine respiratory disease (BRD) in 1,239 high-risk cattle was investigated at four US feedlots. Calves not exhibiting clinical signs of BRD received one of three treatments administered subcutaneously in the neck: physiologic saline at 0.02 ml/kg, tulathromycin at 2.5 mg/kg, or tilmicosin at 10 mg/kg. Each treatment group consisted of 413 calves. Calves with clinical signs of BRD and rectal temperatures of 104 degrees F or higher on days 1 through 14 were considered treatment failures (BRD morbidity). Nasopharyngeal swabs from saline-treated morbidities were submitted for isolation and identification of BRD organisms. Respiratory disease morbidity was highest in calves treated with saline and significantly (P < or = .0001) lower in calves administered tulathromycin or tilmicosin. Morbidity from BRD was significantly (P < or = .0001) higher in calves treated with tilmicosin than in calves treated with tulathromycin. Under conditions of this study, tulathromycin, given to calves at high risk of developing BRD, was significantly more effective in reducing BRD morbidity when compared to both saline- and tilmicosin-treated calves.

Animals↗

Chest imaging in iatrogenic respiratory disease.

Iatrogenic respiratory disease is an important cause of patient morbidity and mortality. Clinical and radiologic findings are nonspecific and diagnosis can be difficult. Therefore, it is important for physicians to be familiar with the iatrogenic diseases for which their patients are at risk, as well as their common radiologic appearances. Causes of iatrogenic respiratory disease include drugs, transplantation, radiation, transfusion, or other miscellaneous therapies.

Aspergillosis↗

[Mortality of respiratory diseases in the years 1981-2000].

Diseases of respiratory system are the 4th or 5th cause of death depending on epidemiological study. Death certificates for permanent residents in Poznań in the years 1981-2000, where underlying cause of death were respiratory diseases were analysed. Deaths from TB were also included which though classified as an infectious disease-affects predominantly respiratory system. Overall male mortality rate from respiratory system diseases had higher values for the most of the period studied, than the same rate for women. In the 90th there was an overall decrease in mortality from the diseases of respiratory system in both sexes with exception of 1999-2000 where there was a rise. At the same time there was a decrease of mortality from pneumonia in both sexes. Up to 1998 a similar tendency in the whole population for the mortality from chronic respiratory diseases was noted. Deaths from influenza and other respiratory system diseases amongst males and females were rare and would not appear in every year under study. Sporadic causes of death from pneumoconiosis were observed mainly in the male population.

Adult↗

Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease.

Three studies conducted at feedlots in Colorado, Idaho, and Texas examined the comparative efficacy of tulathromycin injectable solution for the treatment of cattle at high risk of developing undifferentiated bovine respiratory disease (BRD). Each study randomly allocated 250 calves to receive tulathromycin at 2.5 mg/kg and 250 calves to receive either tilmicosin at 10 mg/kg (Colorado site) or florfenicol at 40 mg/kg (Idaho and Texas sites) on arrival at the feedlot. Calves were housed by treatment group in pens with 50 calves/pen. Beginning 3 days after antimicrobial treatment, cattle were observed for signs of BRD daily until harvest. In all three studies, the treatment success rates at 28 days after treatment and at harvest were significantly higher (P < or = .013) for cattle treated with tulathromycin than for cattle treated with either tilmicosin or florfenicol. Fewer tulathromycin-treated cattle were removed from the group as "chronics" or "mortalities" at 28 days posttreatment (P < or = .014) in all three studies. Tulathromycin demonstrated superior efficacy compared with tilmicosin and florfenicol when treating groups of high-risk cattle before the onset of signs of BRD.

Animals↗