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PubMedDate not supplied

Computed tomography of spondylolisthesis: patterns of associated pathology.

Spondylolisthesis was observed in 165 of 2,500 patients with back pain evaluated by CT. In more than two-thirds of these patients a second structural abnormality was found in association with the spondylolisthesis. The nature and location of this second abnormality varied with the type of spondylolisthesis: spondylolytic or degenerative. Spondylolytic spondylolisthesis, caused by a defect in the pars interarticularis, was associated with foraminal stenosis at the level of the defect in the pars and disk protrusion at the interspace immediately above this level. Degenerative spondylolisthesis, caused by facet joint disease, was associated with disk protrusion and spinal stenosis at the same level as the spondylolisthesis. The advantages and limitations of CT in the evaluation of symptomatic patients with spondylolisthesis are discussed.

Humans↗

PubMed1996

An anatomic evaluation of L5 nerve stretch in spondylolisthesis reduction.

STUDY DESIGN: Lumbosacral spondylolisthesis was simulated using four embalmed human spines, and the path of the L5 nerve was studied. OBJECTIVES: To quantify the change in length of the L5 nerve root associated with reduction of spondylolisthesis, correction of slip angle, and changing disc height. SUMMARY OF BACKGROUND DATA: Stretch injury to the lumbar nerves remains a complication of spondylolisthesis reduction. To date, no anatomic studies have been performed to quantify this effect of reduction on the lumbar nerves. METHODS: The L5 vertebral body and the sacrum of four embalmed human spines were constrained in an adjustable jig, and the length of a simulated nerve was determined for various position variables--sagittal translation (0-100% slip), slip angle (-40 degrees to +20 degrees), and disc height (5 or 10 mm). Two standard points of reference were chosen to represent fixed points along the path of the L5 nerve. An inelastic cord was used to measure the path length between these points as L5 was reduced from 100% to 0% slip. Testing was performed using a 5-mm and a 10-mm disc height. The effect of varying slip angle alone was also studied. RESULTS: The effect of spondylolisthesis reduction and slip angle correction on nerve length varied depending on the location of L5 with respect to the sacrum. There was an increasing effect of partial reduction on nerve length as L5 approached full reduction. Initially, little strain was produced in the L5 nerve as L5 was reduced in higher grade slips. However, as L5 approached full reduction, the strain per increment of reduction increased rapidly. On average, the mean nerve strain was 4.0% for the first 50% of reduction and 10.0% for the second half of reduction. Increasing lordosis relaxed the nerve in high-grade slips and stretched the nerve in fully reduced slips. At 100% slip, the mean nerve excursion decreased 5.1 mm (nerve slackening) when L5 was rotated from +20 degrees to -40 degrees. At 0% slip, the mean nerve excursion increased 3.1 mm (nerve stretch). Increasing disc height directly stretched the L5 nerve. However, given a larger disc height, the strain on the nerve per increment of reduction was less than for the smaller height. CONCLUSION: The findings suggest that the risk of stretch injury to the L5 nerve with reduction of a high-grade spondylolisthesis is not linear; with 71% of the total L5 nerve strain occurring during the second half of reduction, partial reduction may be a significantly safer treatment approach for high-grade spondylolisthesis than complete reduction. Correction of lumbosacral kyphosis in high-grade spondylolisthesis may be protective of the L5 nerve.

Cadaver↗

PubMed2001

Clinical outcome of trans-sacral interbody fusion after partial reduction for high-grade l5-s1 spondylolisthesis.

STUDY DESIGN: A clinical retrospective study was conducted. OBJECTIVE: To evaluate the clinical and radiographic outcome of reduction followed by trans-sacral interbody fusion for high-grade spondylolisthesis. SUMMARY OF BACKGROUND DATA: In situ posterior interbody fusion with fibula allograft has improved the fusion rates for patients with high-grade spondylolisthesis. The use of this technique in conjunction with partial reduction has not been reported. METHODS: Nine consecutive patients underwent treatment of high-grade (Grade 3 or 4) spondylolisthesis with partial reduction followed by posterior interbody fusion using cortical allograft. The average age at the time of surgery was 27 years (range, 8-51 years), and the average follow-up period was 43 months (range, 24-72 months). Before surgery, eight patients had low back pain, seven patients had radiating leg pain, and five patients had hamstring tightness. The average grade of spondylolisthesis by Meyerding grading was 3.9 (range, 3-5). Charts and radiographs were evaluated, and outcomes were collected by use of the modified SRS outcomes instrument. RESULTS: Radiographic indexes demonstrated significant improvement with partial reduction and fusion. The slip angle, as measured from the inferior endplate of L5, improved from 41.2 degrees (range, 24-82 degrees ) before surgery to 21 degrees (range, 5-40 degrees ) after surgery. All the patients were extremely or somewhat satisfied with surgery. The two patients who underwent this operation without initial instrumentation experienced fractures of their interbody grafts. Both of these patients underwent repair of the pseudarthrosis with placement of trans-sacral pedicle screw instrumentation and subsequent fusion. CONCLUSIONS: Partial reduction followed by posterior interbody fusion is an effective technique for the management of high-grade spondylolisthesis in pediatric and adult patient populations, as assessed by radiographic and clinical criteria. Pedicle screw instrumentation with the sacral screws capturing L5 is recommended when this technique is used for the treatment of high-grade spondylolisthesis. According to the clinical and radiographic results from this study, partial reduction and posterior fibula interbody fusion supplemented with pedicle screw instrumentation is an effective technique for select patients with high-grade spondylolisthesis at L5-S1.

Adolescent↗

PubMed2003

Predictive value of pelvic incidence in progression of spondylolisthesis.

STUDY DESIGN: Retrospective analysis of pelvic incidence and other radiographic parameters as a predictor of progression of isthmic spondylolisthesis. OBJECTIVES: To evaluate the predictive value of various radiographic parameters, including pelvic incidence, in determining the risk for progression of lumbosacral isthmic spondylolisthesis. SUMMARY OF BACKGROUND DATA Although pelvic incidence has recently been shown to be positively correlated to the severity of spondylolisthesis, it has not been confirmed as a predictor of spondylolisthetic progression. MATERIALS AND METHODS: Thirty-six patients who have undergone primary posterior lumbosacral fusion for isthmic spondylolisthesis at our institution from 1977 to 2001 were retrospectively analyzed. There were 24 females and 12 males with a mean age of 21.3 +/- 2.0 years (range, 12 to 53 y). Twenty-two patients had high-grade (Meyerding class III, IV, V) and 14 patients had low-grade (Meyerding class I, II) spondylolisthesis, respectively. Factors evaluated included age, gender, neurologic deficits, reason for surgery, and documented evidence of progression. Slip percentage, high-grade or low-grade slip, slip angle, sacral inclination, sacral rounding, trapezoidal L5 vertebra, and pelvic incidence were measured from immediate preoperative standing lateral radiographs. These factors were statistically analyzed for risk of progression. Continuous variables were analyzed using one-way analysis of variance. Nominal variables were analyzed using chi2 test. RESULTS: Pelvic incidence (P = 0.66) was not predictive of spondylolisthetic progression. Of the other radiographic measurements, slip percentage (P < 0.001), slip angle (P = 0.016), and high-grade spondylolisthesis (P < 0.0001) were highly predictive of progression. Interestingly, sacral inclination (P = 0.33) was not predictive of progression. CONCLUSIONS: Pelvic incidence cannot adequately predict the probability of spondylolisthetic progression. Analysis of the other clinical and radiographic parameters revealed that slip percentage and high-grade spondylolisthesis remain the most positive predictors of progression.

Adolescent↗

PubMed2005

Reduction of severe adolescent isthmic spondylolisthesis: a new technique.

STUDY DESIGN: The case of a 14-year-old boy with a severe-grade isthmic spondylolisthesis who underwent reduction and stabilization using this technique is described. OBJECTIVE: To report a new sequential 3-stage procedure for reduction and stabilization of severe adolescent isthmic spondylolisthesis during 1 operative session. SUMMARY OF BACKGROUND DATA: Conventional reduction techniques do not address the important regional anatomic restraints on the L5 nerve root during the reduction maneuver, thereby leading to a high risk of neurologic deficit. Using certain technical refinements could reduce the risk of neurologic deficit. A literature review of reduction of high-grade spondylolisthesis and details of the technique are presented. METHODS: We describe a new 3-stage procedure in a 14-year-old boy who presented with persistent mechanical low back pain, bilateral buttock and leg pain secondary to a severe-grade L5/S1 isthmic spondylolisthesis. Radiologic investigations, including plain radiographs and computerized tomography confirmed the diagnosis. Magnetic resonance imaging showed reduction of signal intensity in the disc at the L5/S1 level. We describe the 3 stages of this technique, which can provide complete sagittal correction. The technical variations to allow a safe reduction of the spondylolisthesis are illustrated. RESULTS: This new procedure can achieve almost complete reduction of severe grades of L5/S1 spondylolisthesis, leading to an excellent cosmetic result and also considerably reduces the risk of neurologic deficit. CONCLUSIONS: In severe-grade lumbosacral spondylolisthesis, isolated posterior fusion, even when supplemented with internal fixation, is not sufficient to prevent deformity progression. Therefore, a combined anterior and posterior fusion is necessary. Reduction of the deformity leads to restoration of normal sagittal alignment with an excellent cosmetic result. Reduction without release of posterior structures may lead to neurologic deficit. This 3-stage shortening procedure can provide sudden reduction of deformity with minimal risk of neurologic deficit. The procedure is technically demanding, and should be performed by spinal surgeons who are familiar with the principles of anterior and posterior fusions.

Adolescent↗

PubMed2006

Dynamic stabilization in addition to decompression for lumbar spinal stenosis with degenerative spondylolisthesis.

STUDY DESIGN: Prospective clinical study. OBJECTIVE: To test whether elastic stabilization with the Dynesys system (Zimmer Spine, Minneapolis, MN) provides enough stability to prevent further progression of spondylolisthesis as well as instability after decompression for spinal stenosis with degenerative spondylolisthesis. SUMMARY OF BACKGROUND DATA: In spinal stenosis with degenerative spondylolisthesis, decompression and fusion is widely recommended. However, patients have donor site pain. In 1994, a dynamic transpedicular system (Dynesys) was introduced to the market, stating that stabilization is possible without bone grafting. METHODS: A total of 26 patients (mean age 71 years) with lumbar spinal stenosis and degenerative spondylolisthesis underwent interlaminar decompression and dynamic stabilization with the Dynesys system. Minimum follow-up was 2 years. Operative data, clinical outcome, and plain and flexion/extension radiographs were obtained and compared to preoperative and postoperative data. RESULTS: Mean leg pain decreased significantly (P < 0.01), and mean walking distance improved significantly to more than 1000 m (P < 0.01). There were 5 patients (21%) who still had some claudication. A total of 21 patients (87.5%) would undergo the same procedure again. Radiographically, no significant progression of spondylolisthesis could be detected. The implant failure rate was 17%, and none of them were clinically symptomatic. CONCLUSIONS: In elderly patients with spinal stenosis with degenerative spondylolisthesis, dynamic stabilization with the Dynesys system in addition to decompression leads to similar clinical results as seen in established protocols using decompression and fusion with pedicle screws. It maintains enough stability to prevent further progression of spondylolisthesis or instability. With the Dynesys system, no bone grafting is necessary, therefore, donor site morbidity can be avoided.

Aged↗

PubMed2006

Computed tomography evaluation of spondylolysis and spondylolisthesis in asymptomatic patients.

STUDY DESIGN: A retrospective radiographic study involving analysis of abdominal and pelvic computed tomography (CT) scans obtained on patients presenting with clinical conditions other than back pain. OBJECTIVE: To determine the incidence of spondylolysis and spondylolisthesis in patients requiring inpatient or emergency department CT evaluation for unrelated abdominal and pelvic conditions. SUMMARY OF BACKGROUND DATA: Spondylolysis and spondylolisthesis are part of a disease process that is thought to be resultant from biomechanical stresses related to bipedal locomotion. The incidence is estimated to be 3% to 10% in the general population. Many of these cases occur without associated symptoms. To our knowledge, there is a relative paucity of data on the use of CT to evaluate the prevalence of these 2 entities in patients seeking medical attention for unrelated conditions. METHODS: Five hundred ten consecutive abdominal and pelvic multi-detector CT scans obtained on a single scanner (Philips MX8000; Eindhoven, The Netherlands) were reviewed. These patients presented with such complaints as abdominal pain and fever, or were imaged as part of their inpatient evaluation for conditions unrelated to lumbar spine pathology. A board certified radiologist and a radiology resident retrospectively evaluated CT scans for lumbar spondylolysis, spondylolisthesis, and associated degenerative changes. A neuroradiologist confirmed all positive cases. RESULTS: Of the 510 cases examined, there were 29 cases of spondylolysis at L5, corresponding to a prevalence of 5.7%. Twenty-three of the cases demonstrated bilateral spondylolysis and 6 unilateral. Sixteen of the 23 cases of bilateral spondylolysis also had spondylolisthesis, 13 of which were grade I, and 3 of which were grade II. In patients 45 years old and younger who did not have spondylolysis or spondylolisthesis, we observed a 32.2% incidence of sclerosis involving the L5 lumbar pedicles. CONCLUSIONS: This study demonstrates a 5.7% prevalence of spondylolysis and a 3.1% prevalence of spondylolisthesis in patients undergoing CT scans of the abdomen and pelvis for unrelated reasons, corresponding to the rate of spondylolysis and spondylolisthesis detected in prospective plain radiographic studies. We observed a 1.2% incidence of unilateral spondylolysis, and approximately 67% of these demonstrated contralateral sclerosis. It is suggested in the literature that sclerosis of the contralateral pedicle seen in cases of unilateral spondylolysis may be a compensatory response to mechanical stresses on an unstable lumbar vertebral body.

Adolescent↗

PubMed2004

Spontaneously stabilized severe dysplastic spondylolisthesis without operation: long-term follow-up of a preteenage patient.

Surgical management is the accepted treatment choice for grade III or IV spondylolisthesis, and many satisfactory clinical and radiologic follow-up results have been reported. Very little, however, has been written about long-term results in preteenage patients in whom dysplastic spondylolisthesis has been treated nonoperatively, especially in those who have > or =50% displacement of the fifth lumbar vertebra on the sacrum. We report an unusual case of spontaneous stabilization of severe dysplastic spondylolisthesis in an 8-year-old girl who presented with grade III spondylolisthesis of L5-S1 and was followed up for >14 years in the absence of surgical intervention. On presentation, she complained of a restriction in forward bending and tightness of hamstrings, but she was undisturbed in her daily activities. Initial radiographs showed severe dysplastic spondylolisthesis; however, magnetic resonance imaging (MRI) performed at age 9 years showed that the amount of listhesis was much less than that seen in the initial radiograph. Routine radiographic follow-ups were chosen over early operative measures until she became a teenager. There was no change in the slip, and unusually a gradual ossification of the cartilaginous promontory of the S1 and the posterior lip of the L5 was observed. At 22 years old, the patient is asymptomatic and not conscious of her cosmetic appearance. Surgical treatment has generally been indicated for patients with grade III or IV spondylolisthesis, because slippage progression has been noted in most reported cases. However, MRI may be a tool for predicting which dysplastic spondylolisthesis cases are more likely to progress and therefore circumvent surgical intervention, while maintaining an excellent outcome.

Adult↗

PubMedDate not supplied

Incidence of spondylolisthesis in ambulatory cerebral palsy patients.

We prospectively studied 50 consecutive ambulatory cerebral palsy (CP) patients to determine the incidence of isthmic spondylolisthesis. In addition, we examined the relationship of hip flexion contractures to development of spondylolisthesis and low back pain. Three patients who had undergone previous spine operation were eliminated from the study group. Of the remaining 47 patients, one patient (2%) demonstrated an asymptomatic grade I spondylolisthesis. Another patient (2%) demonstrated spondylolysis without spondylolisthesis. Only six patients reported occasional low back pain. Pain did not correlate with increasing age, increasing hip flexion contracture, or decreasing sacrofemoral angle. The incidence of spondylolisthesis in this group of ambulatory CP patients with hip flexion contractures is similar to that in the general population. Hip flexion contractures did not predispose the group to spondylolisthesis or low back pain. Periodic screening of asymptomatic ambulatory CP patients for spondylolisthesis is not recommended.

Adolescent↗

PubMed2002

[Surgical treatment of lumbar spinal stenosis associated with unstable degenerative spondylolisthesis].

OBJECTIVES: To assess surgical treatment of lumbar spinal stenosis associated with unstable degenerative spondylolisthesis. METHODS: In 86 patients with lumbar spinal stenosis associated with unstable degenerative spondylolisthesis. (30 men and 56 women, aged from 30 to 77 years), 63 patients complained of lower back pain with both lower extremity pain, 10 patients pain in one leg, and 13 patients only lower back pain. Seventy-two of these patients complained of intermittent claudication, with a walking distance ranging from 10 to 1 000 m. Thirty-two patients had some changes in sensation, motion and reflexes of the foot. According to White' critera, all patients showed dynamic instability of the lesion. Meyerding criteria showed degree 1 in 79 patients, and degree 2 in 7. CT scan was made in 56 patients, MRI in 24 and MRM in 6 before operation. Myelography was performed in 61 patients, and CTM in 6. Stenosis and spondylolisthesis located between L(4) and L(5) in 49 patients, between L(3) and L(4) in 6, between L(5) and S(1) in 25, between L(3) and L(4) and between L(4) and L(5) in 2, and from L(3) to S(1) in 4. The patients with pathological spondylolisthesis were excluded. Lateral recess stenosis of one leg was observed in 10 patients, lateral recess of both legs in 22, and central canal stenosis in 54, of whom 12 patients were associated with protrusion of the lumbar disc. Decompression and autograft with iliac bone and various internal fixation were performed in all patients. RESULTS: The patients were followed up from 8 months to 13 years, longer than 1 year (average 5.6 years) in 81 patients. According to Amundsen et al, excellent results were obtained in 78 patients, good in 5, and fair in 3. Spondylolisthesis was completely reduced in 70 patients of degree 1 (89.9%), and in 6 patients of degree 2 (85.7%). No patient showed slippage aggravated. 74 patients gained bone graft fusion within 3 months and 10 patients within 6 months. Two patients showed pseudoarthrosis during the follow-up. Complications included internal fixation breakage in 1 patient, and delayed infection in 1. CONCLUSIONS: Complete decompression and bone graft fusion are the key to treatment. Decompression and internal fixation improve the symptoms of patients with lumbar spinal stenosis associated with spondylolisthesis. Transpedicle instrumentation can reduce spondylolisthesis and maintain the physical curve of the lumbar.

Adult↗

PubMed1993

The association of mild-moderate isthmic lumbar spondylolisthesis and low back pain in middle-aged patients is weak and it only occurs in women.

This article reports on a cohort-like study of 20 women and 26 men with spondylolisthesis derived from a population of 1147 randomly selected 45-64-year-old subjects against sex-matched control subjects derived from the same source. Seventy-five percent of the spondylolisthetic subjects belonged to Meyerding class I representing mild slip. Low back symptoms during the previous day were more prevalent in women with spondylolisthesis than in control subjects (risk ratio was 7.0; 95% confidence interval 1.4-35.7), and the back pain index was higher (P = 0.028). No significant differences were seen between the groups of men in back symptoms. The use of healthcare facilities and the proportion of subjects receiving invalidity pension because of low back disease did not show any differences between the study groups of either sex. In subjects with spondylolisthesis the degree of vertebral body slip was associated with degeneration of the olisthetic intervertebral disc (P = 0.003), but it was not associated with increased occurrence of back symptoms or pain index. These data suggest that mild-moderate spondylolisthesis detected by chance in a middle-aged population does not predispose to more disabling back pain than back problems experienced by those without spondylolisthesis. However, women with spondylolisthesis have mild back symptoms more often than control subjects, suggesting that in clinical practice and future studies the sex of the patient should be considered in the evaluation of the importance of radiologic spondylolisthesis.

Cohort Studies↗

PubMedDate not supplied

Scoliosis associated with lumbar spondylolisthesis: a case presentation and review of the literature.

BACKGROUND CONTEXT: The association between scoliosis and spondylolisthesis is well documented, but criteria and methods for managing the deformity in patients with debilitating pain are not clear. PURPOSE: To describe correction of scoliosis by internal fixation of the spondylolisthesis. STUDY DESIGN: Case report of a patient with scoliosis developing in association with spondylolisthesis. METHODS: A 17-year-old female presented with a 6-month history of back and leg pain. No spinal curvature was noted in radiographs taken at the onset of symptoms. Significant curvature appeared during the 6-month history of pain in association with an L5-S1 spondylolisthesis. The spondylolisthesis was repaired with posterior pedicle screw instrumentation. RESULTS: The pain and the spinal curvature almost completely resolved after surgery, and the outcome remained excellent 14 months after surgery. CONCLUSION: In the properly diagnosed patient, surgical repair of the spondylolisthesis can relieve pain and correct spinal curvature.

Adolescent↗

PubMedDate not supplied

[Pathogenesis of pediatric spondylolisthesis].

62 children with spondylolisthesis were examined. Functional anatomical studies on 25 growing human spines were performed to analyse their macro morphological behavior before and after spondylolisthesis. The progression of spondylolisthesis is explained as growth disturbance. The high incidence of spina bifida occulta in spondylolisthesis is a mechanical induced osteochondrosis of the dorsal arc. The different morphology of the spondylolisthesis in children depends mostly of the age of the beginning of this disease. The differentiation between the dysplastic and spondylolytic isthmic type of spondylolisthesis is not indicated. Pour prognosis is expected in young children with kyphosis and high ventral dislocation in the involved segment.

Adolescent↗

PubMed1991

Treatment of spondylolysis and spondylolisthesis with Cotrel-Dubousset instrumentation: a preliminary report.

We treated 50 consecutive patients with Cotrel-Dubousset instrumentation (CDI) for symptomatic spondylolisthesis. Average follow-up was 25 months. Fusion in situ was performed in 32 of 44 patients with mild spondylolisthesis, while 12 patients had reduction in conjunction with neural decompression. Two of six patients with severe spondylolisthesis who were treated via a single posterior approach had loss of reduction and nonunion. In another patient a Grade III spondylolisthesis could not be reduced via a posterior approach. Seventy-six percent of the patients had a good clinical result. The rate of solid fusion was 96%. One nerve root compromise recovered completely. One superficial wound infection healed uneventfully. This study suggests that combined anterior and posterior fusion is required for permanent and sufficient correction of severe spondylolisthesis even with CDI. Low-grade spondylolisthesis should be reduced only in conjunction with neural decompression.

Adolescent↗

PubMedDate not supplied

Competitive sports and the progression of spondylolisthesis.

To consider the effects of several years of competitive sports training on children and adolescents with spondylolisthesis, we carried out a retrospective radiologic and clinical study of 86 young athletes with spondylolysis or spondylolisthesis (24 girls and 62 boys between the ages of 6 and 20 years). The mean degree of displacement was 10.1% at the beginning of the observation. The radiologic tests showed an increase in displacement over time in 33 athletes. The average progression of spondylolisthesis in this group was 10.5%. For 36 athletes, spondylolisthesis did not progress during the period of athletic training. In seven athletes, a decrease in the displacement was observed, from 17.9 to 8.9% on average. For 10 athletes, the course of spondylolisthesis could not be determined, because only one lateral radiograph was available. In spite of intensive daily training, the athletes had no symptoms during the entire period of observation, which lasted an average of 4.8 years. In light of our experiments, there is no justification for generally advising children and adolescents with limited spondylolytic spondylolisthesis not to take part in competitive sports.

Adolescent↗

PubMed2000

Symptoms, signs, and functional disability in adult spondylolisthesis.

STUDY DESIGN: A cross-sectional clinical study. OBJECTIVES: To determine whether there are specific symptoms, signs, and functional disability associated with adult spondylolisthesis. SUMMARY OF BACKGROUND DATA: In spite of the common occurrence of adult spondylolisthesis, the symptoms, signs, and disability associated with it have not been analyzed in a large, well-defined group of patients. METHODS: The symptoms, signs, and disability of 111 consecutive patients with adult spondylolisthesis, before randomized treatment with fusion or physiotherapy, were compared with those of 39 patients with nonspecific low back pain before lumbar fusion. The patients completed a questionnaire covering clinical history and symptoms and submitted a pain drawing. The signs were documented. Functional disability and pain were quantified by 12-function and 2-pain visual analog scales, respectively. RESULTS: Sixty-two percent of the patients reported low back pain as well as sciatica, 7% sciatica only, and 31% low back pain only. Specific signs were infrequent. A positive straight leg raising test result in 12% and an L5 sensory disturbance in 13% were the most common. The symptoms were similar in patients with spondylolisthesis and chronic low back pain, but the chronic low back pain group reported more functional disability. Patients with a nonorganic pain drawing (widespread, nonspecific pain) were more often blue collar workers; were more often and longer on sick leave; and reported reduced mental condition, sexual function, functional ability, and more pain than patients with an organic pain drawing (localized, specific pain). CONCLUSIONS: The clinical pattern and functional disability in adult spondylolisthesis and in low back pain of nonspecific origin are similar. Sciatica in adult spondylolisthesis is typically not associated with a positive straight leg raising test result.

Activities of Daily Living↗

PubMed2001

Combined dysplastic and isthmic spondylolisthesis: possible etiology.

STUDY DESIGN: Four cases of combined dysplastic and higher-level isthmic spondylolisthesis were studied. OBJECTIVE: To attempt to understand the possible etiology of this unreported combination. SUMMARY OF BACKGROUND DATA: Dysplastic spondylolisthesis is thought to be hereditary. It is believed that isthmic spondylolisthesis, the more common type, is acquired. Multiple spondylolysis and spondylolisthesis have been reported, but no cases of combined dysplastic and isthmic spondylolisthesis. METHODS: The global and segmental Cobb angles of the lumbar vertebrae and sagittal vertical alignment were measured in four patients who presented with lower back pain and varying degrees of pain radiation to the lower limb. Posteroanterior and lateral radiographs were taken with patients standing barefooted. Three of the patients underwent surgery. The fourth patient refused surgery. RESULTS: The global and segmental Cobb angles were found significantly increased in these patients. Increased segmental extension angles were clearer at the levels above the dysplastic vertebrae and at the level of the isthmic defect. Large anterior translation of the thorax was noted in all cases. CONCLUSIONS: The authors believe that this unusual combination may have resulted from hyperlordosis occurring above the dysplastic vertebrae, which caused increased stresses that led to the isthmic defect. This combination should be investigated in patients with dysplastic spondylolisthesis and hyperlordosis.

Adolescent↗

PubMed2002

Partial lumbosacral kyphosis reduction, decompression, and posterior lumbosacral transfixation in high-grade isthmic spondylolisthesis: clinical and radiographic results in six patients.

BACKGROUND: In an attempt to increase fusion while decreasing the neurologic risk associated with complete reduction of high-grade spondylolisthesis, the authors have used a technique of partial lumbosacral kyphosis reduction, posterior decompression, and pedicle screw transfixation of the lumbosacral junction. OBJECTIVE: To determine if this technique is effective in treatment of high-grade spondylolisthesis. STUDY DESIGN: A retrospective review of six patients with high-grade spondylolisthesis treated by this technique was performed. There were four female patients (ages 16 years [n=2], 23 years [n=1], and 29 years [n=1]) and two male patients (both 13 years of age) with spondylolisthesis ranging from Grade IV to Grade V. All patients presented with pain and radiculopathy. After surgery the patients were evaluated for resolution of symptoms, sagittal alignment, fusion, and satisfaction. The radiographic measurements included the slip angle, the percentage slip, and the sacral inclination. An SRS outcome score was also obtained on all six patients to evaluate postoperative outcome, in terms of pain control, self-image perception, and return to function. RESULTS: The average length of follow-up was 42.6 months (range 24-60 months). All patients evidenced solid fusion by the 6-month follow-up (based on oblique radiographs showing lateral bridging bone masses). The slip angle was improved from 62 degrees to 28 degrees (P < 0.5), whereas there was no significant improvement in the percentage slip or the sacral inclination (89-80% and 28-37 degrees, respectively). No progression of the slip angle or percentage slip was noted on the follow-up radiographs. Complications included two intraoperative dural tears that were identified and repaired. There were no neurologic complications. The SRS outcome instrument demonstrated good postoperative pain control, function, self-image, and satisfaction in all patients. CONCLUSION: In high-grade spondylolisthesis, this posterior approach is safe and effective in obtaining a solid arthrodesis, restoring sagittal balance, and improving function. These results reinforce the impression that it is the partial reduction of the slip angle, not the percentage slip, in high-grade spondylolisthesis that is important in obtaining optimal results.

Adolescent↗