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Results for “SPRAINS AND STRAINS”

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At least 55 records · Page 3Linked to original sources
PubMed1989

A double-blind comparison of flurbiprofen with diflunisal in the treatment of acute ankle sprains and strains.

Fifty patients with acute ankle sprains/strains were treated with either 100 mg flurbiprofen or 500 mg diflunisal twice daily in a double-blind fashion for 18 days or until symptoms of the injury resolved. Tolerability of the drugs was evaluated by recording the occurrence of adverse drug reactions and monitoring laboratory parameters. Efficacy measurements were performed at enrollment and at Visit 2-Day 7, Visit 3-Day 14 and Visit 4-Day 21 to determine relief of symptoms and return to normal activities. Patients in both treatment groups exhibited marked improvement by Visit 2-Day 7 with almost complete recovery by Visit 3-Day 14. Flurbiprofen patients had a significantly shorter duration of therapy. Results from three of the six physician assessments were marginally to significantly superior for patients in the flurbiprofen group. The only reported adverse event was mild gastro-intestinal intolerance in a patient receiving diflunisal. Flurbiprofen and diflunisal appear to be effective and well-tolerated medications for the treatment of acute ankle sprains and strains.

Adolescent↗
PubMed1986

Sprain and strain injuries in the Navy: the possible role of physical fitness in their prevention.

This investigation was undertaken to determine the nature and extent of sprain/strain (S/S) injuries in the Navy and identify occupations that are at high risk of sustaining these injuries. Hospitalization data, including discharge diagnosis and number of days hospitalized, were obtained from inpatient medical records provided by the Naval Medical Data Services Center, Bethesda, MD, and maintained at the Naval Health Research Center, San Diego, CA. All hospitalizations for enlisted personnel in each occupational rate were counted and total number of hospitalizations for each diagnostic category were determined. During the period July 1965 through December 1976, 5584 Navy male enlisted personnel were hospitalized for S/S injuries sustained while on duty. Approximately 56% of these injuries involved the back, 37.5% involved the leg, and 2.9% represent arm and hand injuries. The total number of days hospitalized, i.e., noneffective days, compiled by Navy personnel during this time period, was 82,451. Back injuries accounted for 54.4% of the total number of non-effective days. Findings suggest a relationship between high occupational physical demands and increased S/S injury incidence.

Hospitalization↗
PubMed1989

A comparison of chiropractic, medical and osteopathic care for work-related sprains and strains.

The cost of care and the number of days lost because of work injury were analyzed from information gathered in a postal card survey sent to all Iowa back or neck injury claimants (sprain/strain) on record for 1984. Descriptive findings for the flow of care of the respondents were evaluated and a comparison made of the benefits and costs of care received by patients treated by chiropractic doctors (DCs), medical doctors (MDs) or osteopathic doctors (DOs). The analysis focused on those workers who lost enough time from work to qualify for compensation (4 days or more), whose cases were closed and who received all their care from one health professional. For those who received care from DCs (n = 266), the mean number of compensated days lost from work was at least 2.3 days less than for those who were treated by MDs (n = 494; p less than 0.025) and at least 3.8 days less than for those who were treated by DOs (n = 102; p less than 0.025). Consequently, much less money in employment compensation was paid, on the average, to those who saw DCs. Findings on provider care costs are less clear-cut because care-cost data on only a portion of the cases was recorded on the State records used. For the data available, the median provider cost was highest for patients who saw DCs, but the mean was highest for those who saw MDs. The study showed that 38% of claimants did change doctors. When change of provider occurred, days lost from work and cost of care varied widely across the care options, but generally, fewer workdays were lost and lower amounts of disability compensation and provider cost paid when chiropractic was included in the care pattern.

Absenteeism↗
PubMed2002

Escin/diethylammonium salicylate/heparin combination gels for the topical treatment of acute impact injuries: a randomised, double blind, placebo controlled, multicentre study.

OBJECTIVES: To investigate the clinical efficacy and safety of escin-containing gels in the topical treatment of blunt impact injuries. METHODS: Competitors in soccer, handball, or karate competitions were enrolled within two hours of sustaining a strain, sprain, or contusion and treated three times with the trial gel within a period of eight hours. Patients were randomised to three parallel groups consisting of two active treatment gels, containing escin (1% or 2%), 5% diethylammonium salicylate, and 5000 IU heparin, or placebo gel. Tenderness produced by pressure was measured at 0 (baseline), 1, 2, 3, 4, 6, and 24 hours after enrollment (within two hours of the injury). Tenderness was defined as the amount of pressure (measured by a calibrated caliper at the centre of the injury) that first produced a pain reaction as reported by the patient. RESULTS: A total of 158 patients were enrolled; 156 were evaluated in the intention to treat analysis. The primary efficacy variable was the area under the curve for tenderness over a six hour period. The gel preparations containing 1% and 2% escin were significantly more effective (a priori ordered hypotheses testing controlling the multiple alpha = 5% significance level) than placebo (p(1) = 0.0001 and p(2) = 0.0002 respectively). The treatment effects were 5.7 kp h/cm(2) (95% confidence interval (CI) 2.9 to 8.5) and 5.9 kilopond (kp) h/cm(2) (95% CI 2.9 to 8.8) between 1% escin and placebo and between 2% escin and placebo respectively. These results were supported by secondary efficacy variables. The time to reach the baseline contralateral tenderness value (resolution of pain) at the injured site was shorter in the treatment groups than in the placebo group (p<0.0001). Both active gel preparations produced more rapid pain relief than the placebo gel. No relevant differences were detected between the two active gels. The safety and tolerability of the escin-containing gels were excellent. CONCLUSIONS: Escin/diethylammonium salicylate/heparin combination gel preparations are effective and safe for the treatment of blunt impact injuries.

Administration, Topical↗
PubMed1988

A double-blind comparison of mefenamic acid and piroxicam in acute soft tissue injuries.

Thirty patients suffering from strains, sprains or direct soft tissue injuries were entered into a double-blind trial comparing mefenamic acid and piroxicam. Mefenamic acid was given at a dosage of 500 mg 3-times daily and piroxicam as a single daily dose of 20 mg, for a maximum of 10 days. Both drugs were effective in treating the symptoms associated with acute soft tissue injuries. There were statistically significant improvements in all parameters monitored (pain, functional capacity, sleep disturbance, local swelling and tenderness) by Day 2, except for local swelling in the mefenamic acid group and sleep disturbance in the piroxicam group. By Day 5 all parameters showed improvement. Almost all (90%) of the patients had recovered from their injury in less than 1 week. Both drugs were well tolerated, only 5 patients reporting adverse events (3 on mefenamic acid and 2 on piroxicam).

Acute Disease↗
PubMed1986

Treatment of mild to moderate pain of acute soft tissue injury: diflunisal vs acetaminophen with codeine.

Acute soft tissue injuries create pain and limitation of function. Treatment requires analgesia and time for full recovery. Acetaminophen with codeine (650 mg plus 60 mg, respectively, every 4 to 6 hours) is used frequently as the analgesic of choice. Diflunisal (1,000 mg initially then 500 mg twice a day) vs acetaminophen with codeine was prospectively studied in the treatment of acute mild to moderate pain from soft tissue injuries. Thirty-five patients with acute strains, sprains, or low back pain were randomized to treatment (17 acetaminophen with codeine vs 18 diflunisal). Both groups were similar in the amount of pain and type of injury at initiation of therapy. Patient pain rating went from 3.3 +/- 0.6 to 1.6 +/- 1.5 for acetaminophen with codeine and from 3.3 +/- 0.6 to 1.3 +/- 1.1 for diflunisal. However, 65 percent of acetaminophen with codeine patients experienced side effects, with 35 percent of these patients stopping the medication because of intolerable side effects. In the diflunisal group, 28 percent of the patients experienced side effects and 5 percent had to stop the medication early. Diflunisal was found to be an effective analgesic in mild to moderate pain of acute soft tissue injuries, and caused fewer and more tolerable side effects than did acetaminophen with codeine.

Acetaminophen↗