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Sedentary behavior during postnatal life is determined by the prenatal environment and exacerbated by postnatal hypercaloric nutrition.

The discovery of a link between in utero experience and later metabolic and cardiovascular disease is one of the most important advances in epidemiology research of recent years. There is now increasing evidence that alterations in the fetal environment have long-term consequences on metabolic and endocrine pathophysiology in adult life. This process has been termed "fetal programming," and we have shown that undernutrition of the mother during gestation leads to obesity, hypertension, hyperphagia, hyperinsulinemia, and hyperleptinemia in offspring. Using this model of maternal undernutrition throughout pregnancy, we investigated whether prenatal influences may lead to alterations in postnatal locomotor behavior, independent of postnatal nutrition. Virgin Wistar rats were time mated and randomly assigned to receive food either ad libitum (ad libitum group) or at 30% of ad libitum intake (undernourished group). Offspring from UN mothers were significantly smaller at birth than AD offspring. At weaning, offspring were assigned to one of two diets [control or hypercaloric (30% fat)]. At ages of 35 days, 145 days, and 420 days, voluntary locomotor activity was assessed. At all ages studied, offspring from undernourished mothers were significantly less active than offspring born of normal birth weight for all parameters measured, independent of postnatal nutrition. Sedentary behavior in programmed offspring was exacerbated by postnatal hypercaloric nutrition. This work is the first to clearly separate prenatal from postnatal effects and shows that lifestyle choices themselves may have a prenatal origin. We have shown that predispositions to obesity, altered eating behavior, and sedentary activity are linked and occur independently of postnatal hypercaloric nutrition. Moreover, the prenatal influence may be permanent as offspring of undernourished mothers were still significantly less active compared with normal offspring at an advanced adult age, even in the presence of a healthy diet throughout postnatal life.

Animal Feed↗

Social desirability is associated with some physical activity, psychosocial variables and sedentary behavior but not self-reported physical activity among adolescent males.

This study examined whether controlling for social desirability improved the association between self-reported and objectively measured physical activity among adolescent males and the extent that psychosocial variables predict physical activity after controlling for social desirability. Participants (n=447) were 10- to 14-year old Houston Boy Scouts. Participants completed self-reports of physical activity, sedentary behavior, preferences, self-efficacy and social desirability and wore an MTI accelerometer for 3 days. Correlations were conducted among variables. Regression models were performed to examine the relationships between objectively measured (accelerometer) and self-reported physical activity, objectively measured physical activity and psychosocial variables and self-reports of physical activity and psychosocial variables. All models controlled for social desirability. There were weak associations between self-reported and objectively measured physical activity measures that were slightly improved after controlling for social desirability. Psychosocial variables were strongly associated with self-reports of physical activity, but weakly associated with accelerometer physical activity. Social desirability was positively associated with physical activity preferences (r=0.169) and self-efficacy (r=0.118) and negatively associated (r=-0.158) with self-reported sedentary behavior. Differences in the strength of relationships between self-reported and objectively measured physical activity and psychosocial variables were not a function of social desirability.

Adolescent↗

Socioeconomic status, race, and body mass index: the mediating role of physical activity and sedentary behaviors during adolescence.

OBJECTIVE: To assess how sociodemographic and activity behaviors contribute to adolescent body mass index (BMI). METHODS: One hundred and thirteen adolescents (M = 17 years; 42% Caucasian, 56% African American) were assessed on BMI. Teens reported activity levels and caregivers reported socioeconomic status (SES). RESULTS: Adolescents from lower SES backgrounds, and from minority groups, had higher BMI (r = -.26, p < .01 and t(110) = -3.01, p < .01). Formal statistical mediation tests revealed that sedentary behaviors significantly mediated the association between SES and BMI (Z = 2.31, p < .05), whereas physical activity significantly mediated the race-BMI association (Z = 2.32, p < .05). CONCLUSIONS: Interventions targeting teen BMI could benefit by aiming to decrease sedentary behavior in low SES teens and increase physical activity in teens from minority groups.

Adolescent↗

Smoking and sedentary behavior as related to work organization.

There is little research which has investigated whether working life may affect health behaviors. However, there is data suggesting that smoking as well as leisure activities are affected during times of stress. Both theoretical work and research suggests that work may socialize people such that the use of leisure time for active pursuits, including exercise, may be contingent upon jobs which promote interaction, learning, and activity on the job. In investigating whether the psychosocial structure of work might affect smoking and sedentary behavior, a subsample (n = 7.201) of a representative sample of the Swedish population aged 16-65 years was selected for study. Reports on job characteristics and health behaviors were obtained in personal or telephone interviews and a logistic regression analysis was performed. In general, job demands like shift work, piece work, hazardous exposure, and physical load tended to be associated with smoking and sedentary behavior, whereas job resources, including personal autonomy, were predictive of regular exercise, but unrelated to smoking behavior. Correlational patterns varied somewhat between sexes. The implications of these findings with respect to work organization, considerations in epidemiological research, and the conduct of health promotion programs are discussed.

Health Behavior↗

The role of beverage consumption, physical activity, sedentary behavior, and demographics on body mass index of adolescents.

The percentage of US adolescents who are overweight or at-risk of overweight has increased over the past 20 years. Using data from the third National Health and Nutrition Examination Survey 1988-1994, multivariate regression models of body mass index (BMI) for adolescent males and females aged 12-16 years were developed to examine the relative importance of demographics, beverage consumption, physical activity, and sedentary behavior for maintaining a healthy body weight. The models explained between 11% and 19% of the variance in BMI. Demographic characteristics accounted for roughly one-half of the explained variance in the models. Age was positively associated with BMI for males and females. Family income had a negative association with BMI for females, but no association with BMI for males. The variables for race/ethnicity and region were only occasionally statistically significant. A strong negative association was found between BMI and participation in team sports or exercise programs for both males and females. The estimate of the relationship between television viewing and BMI was positive but not statistically significant. Consumption of regular carbonated soft drinks (RCSD) and fruit drinks/ades--two beverages widely hypothesized to be positively associated with BMI--were not statistically significant in any of the models. Consumption of diet carbonated soft drinks was very low and was positively associated with BMI for females but not for males. The potential impacts of increasing participation in teams or exercise programs, reducing television viewing, and reducing RCSD consumption on BMI were examined. Increasing participation in teams or exercise programs consistently had the largest impact on reducing predicted BMI. The impact of reducing television viewing had the next largest impact. Reducing consumption of RCSD had the smallest impact. Policies that revitalize physical activity and physical education programs for all students--not just student athletes--and educational efforts that discourage sedentary behavior will be far more successful in combating overweight than an undue focus on beverage consumption.

Adolescent↗

Couch potatoes or french fries: are sedentary behaviors associated with body mass index, physical activity, and dietary behaviors among adolescents?

OBJECTIVE: To describe the demographic characteristics of adolescent boys and girls who engage in three sedentary behaviors (television/video use, computer use, and reading/homework), and to explore how each sedentary activity is associated with body mass index (BMI), dietary behaviors, and leisure time physical activity. DESIGN: This study draws on data collected from Project EAT (Eating Among Teens), a school-based survey examining personal, behavioral, and socioenvironmental factors that are associated with nutritional intake among adolescents. SUBJECTS: The study sample consists of 4746 middle and high school students from 31 public schools in a metropolitan area of the upper Midwest. All students were invited to participate. The overall response rate for Project EAT was 81.5%. Data collection was completed during the 1998-1999 school year. STATISTICAL ANALYSIS: Multivariate linear regression was used for examining associations between independent and dependent variables, controlling for age, race/ethnicity, and socioeconomic status. All differences were considered statistically significant at P<.05. RESULTS: Among boys, television/video use and time spent reading/doing homework were positively associated with BMI (P<.05), whereas for girls television/video and computer use were positively associated with BMI (P<.05). High television/video use among boys and girls was associated with more unhealthful dietary behaviors (eg, increased consumption of soft drinks, fried foods, and snacks) (P<.05). In contrast, time spent reading/doing homework was associated with more healthful dietary behaviors (eg, increased consumption of fruits and vegetables) (P<.05). Leisure time physical activity was not associated with television/video use among boys or girls, but was positively associated with computer use and time spent reading/doing homework (P<.05). Applications/Conclusions Messages and advice aimed at reducing time spent in sedentary activities should be targeted at television/video use instead of time spent reading, doing homework, or using a computer. Nutrition education should incorporate messages about the influence of the media and advertising on dietary behaviors.

Adolescent↗

Effects of decreasing sedentary behaviors on activity choice in obese children.

In this study, methods of decreasing highly preferred sedentary behaviors were compared and the consequent effects on activity choice were examined. Following free choice of sedentary and physical activities, 34 obese children either were positively reinforced for decreases in high-preference sedentary activity, were punished for high-preference sedentary activity, had access to high-preference sedentary activity restricted, or had no contingencies on activity (control group). Children randomized to reinforcement and punishment were more physically active on intervention days than the control group. Liking for targeted sedentary activity decreased in the reinforcement group, but increased in the restriction and control groups. Results suggest that reinforcing decreases in high-preference sedentary activity can increase physical activity and decrease liking for targeted sedentary activities.

Analysis of Variance↗

Construct validity of physical activity and sedentary behaviors staging measures for adolescents.

PURPOSE: To evaluate the construct validity of physical activity (PA) and sedentary behaviors (SB) staging measures for adolescents that incorporate the current national recommendations. METHOD: The Progressive Aerobic Cardiovascular Endurance Run, Actigraph accelerometer, and self-reported hours of TV viewing served as criterion measures. Participants were 878 adolescents (M age = 12.74, 53.6% girls, 39.9% non-White). RESULTS: The PA staging measure had mixed evidence of convergent validity and strong evidence of divergent validity. The SB staging measure had strong and generalized evidence of convergent validity but weak evidence of divergent validity, which could be related to inaccurate assumptions about the relation of SB to PA and fitness. Results were generally in the expected direction and provide preliminary evidence for the construct validity and generalizability of both staging measures. However, more research is warranted to validate the staging measures with Actigraph-measured PA and sedentary time. Effect sizes (eta(2) values) ranged from small to large (.02-.63). CONCLUSION: PA and SB stage-of-change measures that are congruent with current national recommendations and appropriate for use among adolescents were partially supported for their construct validity.

Adolescent↗

Longitudinal physical activity and sedentary behavior trends: adolescence to adulthood.

BACKGROUND: There is little national research on longitudinal patterns of physical activity and sedentary behavior in ethnically diverse teens as they transition to adulthood. METHODS: Longitudinal questionnaire data from U.S. adolescents enrolled in Wave I (1994-1995) and Wave III (2001) of the National Longitudinal Study of Adolescent Health (n =13,030) were analyzed in January 2004. Incidence, reversal, and maintenance of achieving five or more weekly bouts of moderate to vigorous physical activity (MVPA) and < or =14 hours of weekly TV and video viewing, computer/video game use (screen time) were assessed. Multinomial logistic regression models examined the likelihood of achieving five or more weekly sessions of MVPA week and < or =14 hours screen time per week as an adolescent and/or young adult, controlling for household income, parental education, age of adolescent, and seasonality. RESULTS: Of those achieving five or more weekly sessions of MVPA and < or =14 hours of weekly screen time as adolescents, few continued to achieve these favorable amounts of activity (4.4%) and screen time (37.0%) as adults. More failed to maintain these favorable amounts of activity (31.1%) and screen time (17.3%) into adulthood. Black versus white females were more likely to maintain less [corrected] favorable amounts of activity from adolescence to adulthood (odds ratio [OR]=3.09; 95% confidence interval [CI]=1.49-6.42), while black males (OR=1.50; CI=1.05-2.14) and females (OR=2.00; CI=1.40-2.87) were more likely than whites to maintain less (versus more) favorable screen time hours. CONCLUSIONS: The vast majority of adolescents do not achieve five or more bouts of moderate physical activity per week, and continue to fail to achieve this amount of activity into adulthood.

Adolescent↗

Sedentary behaviors, physical activity, and metabolic syndrome in middle-aged French subjects.

OBJECTIVE: To study the relationships of time spent in sedentary occupations with the National Cholesterol Education Program-defined metabolic syndrome (MS), taking into account the habitual level of physical activity (PA). RESEARCH METHODS AND PROCEDURES: This was a cross-sectional analysis in 1902 men and 1932 women 50 to 69 years of age participating in the French Supplementation with Antioxidant Vitamins and Minerals study. We assessed past-year PA, television watching or computer use, and reading during leisure with the Modifiable Activity Questionnaire. Subjects who performed at least 150 min/wk of moderate-intensity PA (3 to 6 metabolic equivalent tasks) or 60 min/wk of vigorous PA (>6 metabolic equivalent tasks) were considered as meeting recommended levels. RESULTS: The frequency of most MS components increased with time spent in front of a screen and decreased with increasing PA levels. The likelihood to have MS, adjusted for age, education, and smoking, was decreased by one-third in subjects meeting moderate PA guidelines and by two-thirds in subjects meeting vigorous PA recommendations [odds ratio (95% CI), 0.34 (0.17 to 0.66) in women, 0.44 (0.28 to 0.68) in men] compared with those with insufficient PA. Independently of PA levels, time spent in front of a screen was positively associated with the likelihood to have the MS in women [odds ratio (95% CI), 3.30 (2.04 to 5.34)], whereas in both sexes, no association was found with time spent reading. DISCUSSION: The relationship of the MS with a sedentary lifestyle differs according to sex and type of sedentary occupation. These results suggest the need to assess selected indicators of sedentary behavior in preventive programs.

Aged↗

Effects of decreasing sedentary behavior and increasing activity on weight change in obese children.

Obese children 8-12 years old from 61 families were randomized to treatment groups that targeted increased exercise, decreased sedentary behaviors, or both (combined group) to test the influence of reinforcing children to be more active or less sedentary on child weight change. Significant decreases in percentage overweight were observed after 4 months between the sedentary and the exercise groups (-19.9 vs. -13.2). At 1 year, the sedentary group had a greater decrease in percentage overweight than did the combined and the exercise groups (-18.7 vs. -10.3 and -8.7) and greater decrease in percentage of body fat (-4.7 vs. -1.3). All groups improved fitness during treatment and follow-up. Children in the sedentary group increased their liking for high-intensity activity and reported lower caloric intake than did children in the exercise group. These results support the goal of reducing time spent in sedentary activities to improve weight loss.

Child↗

Comparability and reliability of paper- and computer-based measures of psychosocial constructs for adolescent physical activity and sedentary behaviors.

This study assessed the comparability and reliability of paper-based and computer-based administration of psychosocial construct measures related to adolescents engaging in physical activity and sedentary behaviors. Adolescents (n = 76; 55% girls, 49% Hispanic, 18% non-Hispanic-white; M age = 13 years) completed measures of behavior change strategies, self-efficacy, decisional balance, family and peer influences, enjoyment, activity choices, and environmental influences. Overall, the adolescents provided equivalent responses on paper and computer formats. Reliability estimates were generally good for the multiple-item constructs, but single-item measures tended to demonstrate low reliability. Average scale internal consistency was significantly higher for measures administered with the computer format compared to the paper format, but test-rest reliability estimates were not significantly different between formats.

Adolescent↗

The effects of physical activity and sedentary behavior on cognitive health in older adults.

Physical activity has been shown to be positively associated with cognitive health, but the mechanisms underlying the benefits of physical activity on cognitive health are unclear. The present study simultaneously examined two hypotheses using structural equation modeling (SEM). The depression-reduction hypothesis states that depression suppresses cognitive ability and that physical activity alleviates dysphoric mood and thereby improves cognitive ability. The social-stimulation hypothesis posits that social contact, which is often facilitated by socially laden physical activities, improves cognitive functioning by stimulating the nervous system. Sedentary behavior in the absence of physical activity is expected to exert an inverse relationship on cognitive health through each of these hypotheses. Community-dwelling elders (N = 158) were administered a variety of measures of cognition, depression, social support, and physical activity. SEM techniques provided partial support for the social-stimulation hypothesis and depression-reduction hypothesis. Implications for treating depression and improving cognitive functioning are discussed.

Aged↗

Health Opportunities with Physical Exercise (HOPE): social contextual interventions to reduce sedentary behavior in urban settings.

Physical activity interventions targeting social and physical environments of the urban poor hold promise in improving health outcomes in underserved communities. This study randomly assigned overweight, sedentary, economically disadvantaged adults to one of three intervention conditions at The Hope and Healing Center, a large inner-city health facility providing numerous options for exercise. Within the tenets of Social Action Theory, the Health Opportunities with Physical Exercise (HOPE) trial will test the efficacy of two behavior change models, social support and patient-provider interaction, to increase physical activity. In addition to a standard care condition, in which patients have open access to Hope and Healing physical activity programming, patients were assigned to one of two behavior change interventions. Those assigned to patient-peer receive face-to-face, systematic and scheduled encouragement from study-trained 'peer' interventionists at the facility. Patients assigned to patient-provider receive face-to-face, systematic and scheduled encouragement provided by study-trained 'provider' interventionists also at the facility. The primary outcomes of change in exercise behavior will be documented by self-reported physical activity and confirmed by fitness testing at baseline, 6, 12 and 24 months during the 1 year of active intervention and 1 year of relapse prevention follow-up. Intervention conditions will be compared on psychosocial mediators including motivational appraisals, ratings of social support, rapport, problem solving and self-efficacy for overcoming barriers to increased physical activity. Novel aspects of this intervention include: (1) delivery of socially based physical activity interventions to an economically disadvantaged urban population, (2) reduction of environmental barriers to be physically active and (3) emphasis on social interactions influencing health habit change. Results of this study have the potential to identify mechanisms of behavior change that could be adopted by physical activity interventions aimed at reducing sedentary behavior and health disparities in high-risk, underserved populations.

Exercise↗

The effectiveness of a point-of-decision prompt in deterring sedentary behavior.

Individuals using a university library were observed using stairs or elevators to travel up one to three floors. After a baseline assessment, a sign was posted by the elevator to discourage elevator use over a five-week period. A hierarchical log linear analysis indicated that stair use increased significantly after the intervention moderated by day of the week, sex, and age. The study suggests that point-of-decision prompts to deter sedentary activity may be effective.

Adult↗

Causal relationships between modifiable risk factors and heart failure: A comprehensive Mendelian randomization study.

Heart failure threatens human health across the globe. Comprehensively identifying its risk factors has public health importance. This work utilized the Mendelian randomization (MR) method to evaluate the effects of over 200 modifiable factors on heart failure. The data from genome-wide association studies (GWAS) was used, with the sample size ranging from 711 to 1232,091. Two distinct GWAS datasets for heart failure were employed for results validation. The inverse variance weighted (IVW) method was used and other supplementary models were employed for comparison. Sensitivity analysis was conducted to verify the results. After integrating the MR estimates derived from heart failure GWAS datasets from integrative epidemiology unit (IEU) and Finngen, we found that body measurement indices like body mass index, whole body fat mass, trunk fat mass, basal metabolic rate, body fat percentage, waist circumference, and waist-hip ratio, were associated with a higher risk of heart failure. Similarly, smoking behavior, sedentary behavior, overall health rating, and type 2 diabetes were determined to increase the risk of heart failure. In contrast, college or university degree showed a protective effect on heart failure. Among these significant findings, body mass index, whole body fat mass, trunk fat mass, basal metabolic rate, body fat percentage, overall health rating, smoking initiation, waist circumference, lifetime smoking index, college or university degree, sedentary behavior, waist-hip ratio, and type 2 diabetes were replicated validated. This MR work figured out that obesity, socioeconomic factors, lifestyle factors, and metabolic features showed broad relations with heart failure. The findings would provide evidence for future policy development for the management of heart failure.

Humans↗