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[Case of giant meningioma of the small wing of the sphenoid bone in a 9-year-old boy].

The authors report a boy aged 9 years in whom a giant meningioma of the small wing of the sphenoidal bone was removed surgically. Attention is called to the rarity of these tumours in the first decade of life. Developmental retardation, speech beginning at the age of 4 years, large head and epileptic seizures developing at the age of 7 years without signs of intracranial hypertension suggested the possibility of organic brain disease and development of massive hemiparesis, speech disturbances and choked disc in the last period of the disease were the cause of referral of the child to a neurosurgical unit. Plain skull films and angiography demonstrated changes typical of raised intracranial pressure and presence of an expanding lesion in the left cerebral hemisphere. Meningioma was found on operation hidden within the left frontal and temporal lobes but connected by means of a narrow band to the dura of the small wing of the sphenoidal bone. A good result was obtained. Follow-up examination after 2 years demonstrated slight neurological abnormalities and a very good general state of the child.

Age Factors↗

Communication of the intracranial space with sphenoid bone marrow in mice.

Tritiated thymidine and Ehrlich ascites tumour cells were injected intrathecally in adult Balb/c mice. Thymidine penetrated easily into the sphenoid bone marrow, where it labelled numerous leukocytes. The microvessel wall constituted a partly penetrable barrier against the infiltration of Ehrlich ascites tumour cells from arachnoid space into the bone marrow. A possible physiological role of the drainage of substances from the brain into the bone marrow is discussed.

Animals↗

Giant cell tumour of the sphenoid bone with dural extension.

A case of giant cell tumour of the sphenoid bone is reported. Besides the familiar presentation with headaches, ocular manifestations, and upper cranial nerve lesions, this case showed previously undescribed features such as grand mal seizures, hemiparesis with facial palsy, and dural extension. The reported high incidence in females is questioned. The tumour histologically showed some cartilage.

Adult↗

Intraosseous lipoma of the body of the sphenoid bone.

A case of intraosseous lipoma arising from the body of the sphenoid bone with intrasellar and suprasellar components is reported. This is the first report of this uncommon tumour occurring in an atypical intracranial site, producing the locally invasive and pressure effects of visual failure and hypopituitarism. The diagnosis was based on computed tomographic (CT) and magnetic resonance (MR) imaging with histological confirmation following frontal craniotomy.

Female↗

Nuclear scattering radiography of the spine and sphenoid bone.

Nuclear scattering radiographs of a portion of a spine and a sphenoid bone have been obtained using a 1 GeV proton beam. The ability of the method to yield three-dimensional representations is illustrated by three series of adjacent pictures corresponding to the three orthogonal planes (elementary volume: 5.2 mm3 and 0.9 mm3). The sensitivity of the method is discussed. Nuclear scattering radiographs are compared with ones obtained by conventional X-ray tomography and computed tomography. Nuclear scattering radiography also may be used to analyze the partition of hydrogen within the tissures. Hydrogen radiographs obtained in this way are shown.

Elementary Particles↗

Giant-cell tumor of the sphenoid bone. Review of 10 cases.

Giant-cell tumor rarely affects the sphenoid bone. Ten cases of this tumor seen at the Mayo Clinic are reviewed, bringing the number of cases in the world literature to 31. These tumors, which present in the second and third decades of life and are slightly more frequent in women than in men, may present with various symptoms, including headache, visual field defects, blindness, and diplopia. The symptom complex and roentgenographic findings are seldom, if ever, sufficiently characteristic to allow preoperative diagnosis. The microscopic differential diagnosis of giant-cell tumor of the sphenoid region includes giant-cell reparative granuloma, aneurysmal bone cyst, fibrous dysplasia, and "brown tumor" of hyperparathyroidism. Interesting features of this series include the presence of multifocal giant-cell tumor in one case, and the absence of Paget's disease of bone in every case. Complete follow-up review in these cases allowed a discussion of therapy and prognosis; it appears that subtotal excision with postoperative radiation therapy is the treatment of choice. While the histological appearance of giant-cell tumor is characteristic, caution must be exercised in interpreting small samples, and various reparative and metabolic disorders must be considered in the differential diagnosis.

Adolescent↗

Giant cell tumor of the sphenoid bone.

OBJECTIVE AND IMPORTANCE: Giant cell tumor of the sphenoid bone is extremely unusual. This tumor is usually located in long bones and is rarely located in the cranial vault. It must be differentiated from reparative granuloma and the Brown tumor of hyperparathyroidism. This case report is only the second involving a patient in the first decade. CLINICAL PRESENTATION: A 9-year-old girl presented with cephalgia and diplopia. Radiographic imaging revealed an erosive mass in the clivus. INTERVENTION: The patient underwent an extended transphenoidal resection of the clivus. This was followed with 57.6 CGE in 32 fractionated doses. CONCLUSION: At 1 year follow-up, the tumor remains stable. Based on anecdotal evidence, attempted resection with adjuvant radiation therapy allows for long-term survival in these patients.

Case Reports↗

Giant cell tumor of the sphenoid bone.

The clinical and histological features of two cases of giant cell tumor of the sphenoid bone are described. Both presented with similar symptoms and signs, comparable to previously described cases. The problems in histological differential diagnosis are discussed and radiotherapy as the treatment of choice is suggested.

Adolescent↗

Giant cell tumour of the sphenoid bone with coincidental galactorrhoea--a case report.

A case of the rare giant cell tumour involving the sphenoid bone is reported. The usual presentation of these tumours is headache and cranial nerve deficits. This 25-year-old lady presented with oligomenorrhoea and galactorrhoea. Investigations demonstrated an asymptomatic erosive mass lesion in the sphenoid with suprasellar extension and extension into the nasopharynx. The tumour was partially resected via the transphenoidal route. The differential diagnosis and treatment of these lesions are discussed.

Adult↗

[Giant cell tumor originating in the sphenoid bone: a case report].

The authors report a case of giant cell tumor originating in the sphenoid bone. A 29-year-old woman presented with headache and diplopia. Bilateral ophthalmoplegia developed and MRI showed rapid growth of the tumor in spite of transnasal removal and conventional radiation therapy. The second transnasal surgery was performed 3 weeks after completion of radiotherapy. The symptoms were relieved except for right abducens palsy. Chemotherapy with cisplatin and etoposide was started after the second operation. The patient regained full ocular movement several months after the operation. Clinical remission has continued for four years. We conclude that the combination of repeated operations in the initial phase of rapid tumor growth, irradiation and chemotherapy is important to achieve tumor control.

Adult↗

[Cerebral aneurysm associated with meningioma in the area of small wing of the sphenoid bone].

A patient is described in whom removal of meningioma situated on the small wing of the sphenoid bone was followed by haemorrhage from an aneurysm of the middle cerebral artery. The aneurysm was recognized only after angiography was done after the operation for brain tumour. The problem of lack of visualization of aneurysms situated in the vicinity of brain tumours and diagnostic difficulties in cases of coexistence of these diseases are discussed.

Adult↗

[Giant cell tumors of the sphenoid bone. Report of 3 cases and review of the literature].

Three cases of giant cell tumor of the sphenoid bone are reported together with a revision of the previously reported cases in the neurosurgical literature. The importance of this tumor in the neurosurgical pathology is stressed, mainly to the impossibility of a correct diagnosis on a clinical and radiological basis. A good prognosis is possible with a least agressive surgery, transphenoidal biopsy and decompression, folowed by radiotherapy.

Adult↗

Infected epidermoid cyst of the sphenoid bone.

An infected epidermoid cyst presented on CT as a primarily dense, sclerotic expansile lesion in the greater wing of the sphenoid bone. Presumably, infection was responsible for the atypical appearance.

Aged↗

[Recurrent meningioma. Analysis of 43 surgical interventions in meningioma of the sphenoid bone].

A total of 43 operations were carried out in 37 patients with a meningioma of the wing of the sphenoid bone or a Tuberculum sellae meningioma. In 18 cases the primary extirpation could be performed and in 18 patients the intervention only consisted of a resection. The removal of any meningioma tissue was classified as an extirpation. If a residual part of whatever size of the tumour was left, the intervention was declared to be a resection. Six patients died, 31 were submitted to a control examination. All 14 patients in whom an extirpation was carried out showed no signs of a renewed tumour growth within the observation period of 2 to 10 years after obtaining the computer-tomographical findings. In six of the 16 patients in whom only a resection was possible a second operation was carried out. An extirpation could be performed in four of these patients. Among the remaining ten patients (period of observation 2 to 6 years) five showed a further increase of the tumour size, in four patients no tendency of a growth could be proved, and one patient had died. In the postoperative assessment we distinguish between a residual tumour and a new tumour growth. A renewed tumour growth is present if the computer tomogram shows signs of meningioma tissue although earlier postoperative checks had not shown this. In the postoperative control examinations the residual tumours should be differentiated with respect to their importance as (a) a residual tumor with a growth tendency and (b) a residual tumour without a growth tendency.

Adolescent↗

Osteoma of the lateral pterygoid plate of the sphenoid bone.

A rare case is reported of an osteoma protruding into the pterygomandibular space from the lateral pterygoid plate of the sphenoid bone. The procedure of the diagnosis and treatment is described. In this case, computed tomography (CT) was the most useful in making a differential diagnosis. That the pulling force of the medial pterygoid muscle might be a causative agent in the growth of this osteoma is considered.

Adult↗