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Results for “THYMUS NEOPLASMS”

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PubMed1996

[Thymus carcinoid associated with type 1 multiple endocrine neoplasm syndrome].

Thymus carcinoid tumors are unusual and can be differentiated from thymomas by clinical, histological and prognostic characteristics. The clinicopathological findings of a new case of carcinoid tumor of the thymus associated with type 1 multiple endocrine neoplasm, the presentation of which was conditioned by its metastasis, is herein presented.

Adenoma↗
PubMed1998

Carcinoid tumor of the thymus: a unique neoplasm of the mediastinum.

In this report, we describe a patient with a thymic carcinoid and the evolution of his disease for the past 5 years. Due to the distinct nature of thymic carcinoids, their unique biologic and endocrine properties, and the variety of available treatment options, it is important to differentiate this entity from other mediastinal tumors. The use of immunohistochemical studies or electron microscopy by the pathologist permits more accurate differentiation and diagnosis.

Carcinoid Tumor↗
PubMed1988

Neuroendocrine neoplasms of the thymus.

Neuroendocrine tumors of the thymus bear many similarities to "carcinoids" and "oat-cell carcinomas" in other organs, and are clinicopathologically distinct from thymomas, thymic seminomas, and other primary tumors of this gland. They are associated with Cushing's syndrome or multiple endocrine neoplasia in 35% of cases, and are often locally aggressive. Approximately 30-40% of patients have distant metastases of their tumors that ultimately result in fatality, since the response of thymic neuroendocrine neoplasms to irradiation and chemotherapy is poor. Ultrastructural studies and immunohistochemical stains for chromogranin, protein gene product 9.5, and synaptophysin are effective tools for the diagnosis of thymic carcinoid and oat-cell carcinoma.

Diagnosis, Differential↗