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[Thyroglossal cyst: retrospective study of 58 cases. Results of the Sistrunk operation].

Cysts of the thyroglossal duct are one of the most common causes of benign neck masses. They generally occur in young patients and are caused by a defect in thyroglossal duct closure, which sometimes is in close contact with the hyoid. Often several tracts are present. The most effective surgical procedure was originally described by Sistrunk in 1920 and modified in 1928. This technique is based on the removal of the central portion of the hyoid bone. This procedure has successfully reduced the number of recurrences compared to local excision of the cyst. A retrospective review was made of 58 cases to evaluate surgical results, especially recurrence rate, in relation to the resection or preservation of the hyoid bone. Results were compared with published series.

Adolescent↗

Intrahyoid thyroglossal cyst.

A rare case of an intrahyoid thyroglossal duct cyst in a 63-year-old woman is reported. The pertinent literature is discussed.

Female↗

Thyroglossal cysts in children.

Of 69 cases of midline cervical swelling in children, the correct diagnosis was made in only 38 (55 per cent). Fifty cases of thyroglossal cyst or abscess were treated and 38 per cent suffered recurrence. Apart from failures in diagnosis, the main reasons for preventable recurrence were delay in surgery, failure to resect part of the body of the hyoid bone and a tendency to excise that portion of the duct above the level of the hyoid with insufficient surrounding muscle. In cases without florid abscess formation, the aim should be to perform a radical operation as soon as possible, then cure can be guaranteed at the first operation. Recurrence may occur many years after an apparent cure. Cysts in the submental region are not often recognized as being of thyroglossal duct origin.

Child↗

Papillary thyroid carcinoma in thyroglossal duct cyst.

Thyroglossal duct remnants are the most common midline neck swellings, but carcinoma is found in approximately 1% of these lesions. The cysts are usually asymptomatic and the presentation of the patient with carcinoma is indistinguishable from the common cyst. Papillary adenocarcinoma comprises 75-85% of the tumors reported. A 36-year-old woman underwent Sistrunk procedure for excision of a thyroglossal cyst. No thyroid abnormality was noted pre-operatively nor during the surgical examination. The histopathological examination revealed papillary carcinoma. She has been maintained on thyroxine suppression and was doing well at 14 months' follow-up. Carcinoma of the thyroglossal duct cyst is rare. The ultrasonographic examination should be performed pre-operatively for thyroid gland study. The main question is what to do with the thyroid gland. There still is controversy about thyroid removal for a papillary carcinoma, but all the patients should receive suppressive doses of thyroid hormone. As the cure rate is 95% for the patients whose thyroid is preserved and further postoperative complications are avoided, we can consider that the optimal surgical procedure for thyroglossal duct carcinoma is the same as that for the benign cyst.

Adult↗

Computed tomography and the thyroglossal duct cyst.

Thyroglossal duct cysts (TDC) classically present as midline neck masses in close relation to the hyoid bone; yet--not uncommonly--their locations may be varied from the midline and from the hyoid. By means of the diagnostic modality of computed tomography (CT), high-resolution images of several cases of alternate presentations and locations of the TDC are examined. Included are examples of TDC in the suprahyoid, transhyoid, infrahyoid, and lateral positions. The potential value of CT in the diagnosis of the unusual cyst will be demonstrated and discussed.

Adult↗

[Thyroglossal duct cyst].

Thyroglossal duct cysts are embryologic anomalies arising from epithelial remnants of the duct left after the descent of the developing thyroid. Clinical, operative and pathological findings in 124 patients operated on in the past 14 years were analyzed. There were 60 males and 64 females. 69 (56%) were under 10 years of age and the youngest was 6 months old. 26 (21%) were over the age of 30, and the oldest was 72 years old. All excisions were performed in accordance with the Sistrunk procedure, which includes removal of the body of the hyoid bone. Overall recurrence was 6.4%, but in infected cysts or cysts with a fistula to the skin, it was 3.5 times greater. In 20% the cyst was located off the midline. The lining of the cysts was cuboidal, columnar, pseudostratified or stratified squamous epithelium, and varied according to the location of the cyst. There were no malignant changes.

Adolescent↗

Evaluation and management of a carcinoma arising in a thyroglossal duct cyst.

Thyroglossal duct remnants are the most common congenital cystic lesions of the neck; however, a carcinoma arising in these structures is rare. Two new cases of a papillary adenocarcinoma arising in a thyroglossal duct cyst are presented. Preoperative evaluation, operative management, and postoperative care are discussed. Initial evaluation consisting of a thorough head and neck examination, palpation of the thyroid gland, thyroid function tests, and selective use of thyroid imaging is recommended. Removal of the cyst and tract in the manner described by Sistrunk is advocated. If an adenocarcinoma is found in the cyst and if a carcinoma is found in the thyroid gland or a thyroid scan reveals a nodule, a total thyroidectomy is recommended. A modified neck dissection and total thyroidectomy is advocated for cervical metastases. Postoperatively, thyroid suppression and long-term follow-up are encouraged. A squamous cell carcinoma arising in a thyroglossal duct remnant appears more aggressive and requires complete excision and, for confirmed cervical metastases, radical neck dissection and postoperative radiation therapy.

Adenocarcinoma, Papillary↗

[Diagnosis and treatment of thyroglossal cysts and fistulae (Sistrunck or Schlange?): reflections on 40 cases].

40 cases of cysts and fistulas of the thyroglossal tract duct offer to the authors occasion to review the rare problems of diagnosis raised by this pediatric pathology. They compare the results of surgery obtained by the classic technic of Sistrunck (1920) versus the Schlange's operation (1893) which remove the cyst with the hyoid bone's body only. The average of age is 17 years. A location of a thyroglossal cyst in the submandibular area was noted during operation. Sistrunck's operation was performed in 21 cases (52.5%) and the Schlange's one in 14 cases (35%) without recurrence. 4 cases (10%) recurrences were noted, all after simple cystectomy. Removal of the hyoid bone's body appear to us as the key of success in the surgery of thyroglossal anomalies.

Adolescent↗

Thyroglossal duct cyst.

Thyroglossal duct cyst is a midline congenital nonodontogenic cyst seen predominantly in children. The clinical history and physical examination, along with characteristic radiographic findings, enable the physician to make a preoperative diagnosis with a high degree of certainty. Surgery is the definitive treatment.

Child↗

Papillary carcinoma in a giant thyroglossal duct cyst.

Thyroglossal duct cysts (TGDCs) are common, however, a malignancy occurring in a TGDC is rare. The presence on an underlying malignancy is clinically occult but may be detected on preoperative imaging studies. We describe the CT findings of a papillary carcinoma occurring in a TGDC.

Adult↗

An unusual presentation of thyroglossal duct cyst.

Thyroglossal duct cyst usually presents as a painless swelling in the mid-line of the neck. This is the first documented case of an acute presentation of hoarseness and multi-loculated swelling. It also contrasts the limitations of ultrasonography with the accuracy of magnetic resonance imaging in such atypical swellings.

Adult↗

Primary papillary carcinoma in a thyroglossal duct cyst.

Thyroglossal duct cysts (TDC) are the most common congenital anomalies of the thyroid gland and less than 1% of them become malignant. The malignancy most often found is papillary carcinoma. The diagnosis is usually made postoperatively. Controversy exists whether TDC are primary or secondary and also as for their treatment regime. In this case report, we present a 30-year-old woman with papillary carcinoma of the TDC, identified only by pathology after surgical ablation by Sistrunk's procedure. Invasion of the carcinoma to the adjacent tissues or lymph node metastases were not found. Thyroid function tests were normal as well as the thyroid scan. After a two-year follow up, the patient remained asymptomatic with no evidence of recurrence, as tested clinically and by ultrasonography. Since our patient had no marginal invasion of the carcinoma in the surrounding tissues or lymph node metastases, we recommended the Sistrunk's surgical procedure, suppressive treatment by thyroid hormones and long term follow-up.

Adenocarcinoma, Papillary↗

Thyroglossal cyst carcinoma.

A case of papillary thyroid carcinoma arising in a thyroglossal duct cyst is presented. The tumour is rare and is generally not expected preoperatively. The clinical and pathological characteristics are emphasized, the treatment is discussed, and the importance of excision of thyroglossal duct cysts is stressed.

Adolescent↗

[Case of thyroglossal duct cyst].

Thyroglossal duct cyst has been reported to be derived from epithelial rests in the remnants of the thyroglossal duct produced by the descendant of the thyroid anlage. A 34-year-old man consulted our clinic with complaints of painless swelling located in the median cervical region. This tumor was excised under general anesthesia, according to the Sistrunk method. Histopathological findings showed that the inner side of the cyst wall was covered with the stratified squamous epithelium and cliniated columnar epithelium, and the outer layer, thickened connective tissue. No complications or recurrence occurred 2 years and half after the operation.

Adult↗