PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “TONGUE DISEASES”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 55 records · Page 3Linked to original sources
PubMed1996

Ultrasound versus physical examination in staging carcinoma of the mobile tongue.

Surgical therapy for early lesions of the tongue should have the potential to be both oncologically sound and easy to rehabilitate. Obviously, the amount of tongue left behind after surgery is proportional to the post-operative function. Hence accurate mapping of the diseased tongue is of paramount importance in order to limit or extend the resection margins. We have evaluated the use of ultrasound in carcinoma of the tongue, and also compared its relative accuracy with physical examination for determining the extent of growth, keeping the histopathological size as a gold standard. We found that ultrasound is more accurate in detecting T2 and T3 tumours than T1 lesions. Intraoral sonographic mapping may be the answer for such small lesions. In addition, ultrasonography is beneficial in showing spread to contiguous areas of the tongue. However, post-radiation fibrosis and frank residual disease were not differentiated accurately by ultrasound. Thus ultrasonography can be an effective investigative tool and together with physical examination it can increase diagnostic accuracy leading to precise surgery for carcinoma of the tongue.

Carcinoma, Squamous Cell↗
PubMed1996

Halitosis. A common oral problem.

Halitosis is caused primarily by bacterial putrefaction and the generation of volatile sulfur compounds. Ninety percent of patients suffering from halitosis have oral causes, such as poor oral hygiene, periodontal disease, tongue coat, food impaction, unclean dentures, faulty restorations, oral carcinomas, and throat infections. The remaining 10 percent of halitosis sufferers have systemic causes that include renal or hepatic failure, carcinomas, diabetes or trimethylaminuria. Modern analytical and microbiological techniques permit diagnosis of bad breath. Management of halitosis involves maintaining proper oral hygiene, and periodontal treatment, including tongue brushing.

Bacteria↗
PubMed1999

Architectural organization of filiform papillae in normal and black hairy tongue epithelium: dissection of differentiation pathways in a complex human epithelium according to their patterns of keratin expression.

BACKGROUND: An inadequate understanding of the complex morphologic characteristics of human filiform papillae has hampered the histopathological characterization of disorders affecting tongue keratinization. To better define the 3-dimensional cytoarchitecture of tongue epithelium, we performed detailed immunohistochemical analyses of normal and black hairy tongue tissues using a panel of antikeratin antibodies. OBSERVATIONS: The dome-shaped base of the human filiform papilla (primary papilla) is surmounted by 3 to 8 elongated structures (secondary papillae). These secondary papillae are composed of a central column of epithelial cells expressing hair-type keratins and an outer rim of cells expressing skin-type keratins. The epithelium overlying the primary papillae and between the individual primary papillae express esophageal-type keratins. In black hairy tongue disease, there is a marked retention of secondary papillary cells expressing hair-type keratins. CONCLUSIONS: Using a panel of antikeratin probes, we define the precise topographical localization of cell populations undergoing 3 distinct differentiation programs in dorsal tongue epithelium. Comparative analyses of black hairy tongue specimens indicate that defective desquamation of the cells in the central column of filiform papillae results in the formation of highly elongated, cornified spines or, "hairs"--the hallmark of this disease.

Antibodies↗
PubMed1982

One-stage reconstruction of the hypopharynx using myomucosal tongue flap and dermal graft.

Reconstruction of the hypopharynx following total laryngectomy and total pharyngectomy provides a one-stage procedure to reconstitute the food conduit. A myomucosal advancement tongue flap forms the anterolateral walls, and the dermal graft forms the posterior wall of the reconstruction. Sixteen patients underwent reconstruction by this method. Thirteen required total laryngectomy and total pharyngectomy for extensive carcinomas. Two other patients who had previous laryngectomy and hypopharyngeal recurrence had pharyngectomy and repair by tongue flap and dermal graft. A third patient required laryngopharyngectomy following recurrence after supraglottic laryngectomy. No postoperative deaths have occurred. Anteriolateral defects of up to 8 cm in size can be reconstructed providing the neck can be flexed. Larger posterior defects superior to the eustachian tube can be closed. In two patients minor fistulas developed which closed spontaneously. One other patient had a delayed wound dehiscence and infection with fistula and carotid blowout. The patient had undergone previous surgery and radiotherapy. Deglutition was good to excellent in most patients. Three patients required esophageal dilatation with resolution. Cinegraphic studies have demonstrated the tongue to propel a bolus and to modulate speech which shows this repair to create a dynamic conduit. One patient had difficulty in swallowing because the left hypoglossal nerve was resected. Seven patients were alive with no evidence of disease 2 to 30 months postoperatively. Four patients who were free of their original disease died from other causes. Four patients died from original disease 5 to 23 months postoperatively. At present, one patient is alive with disease. Tongue flap and dermal graft provide a reliable and one-stage reconstruction following laryngopharyngectomy and should be considered as an alternative to distant flap and intestinal interposition reconstructive procedures.

Carcinoma↗
PubMed2006

Oral malodor: a review of the literature.

Oral malodor or halitosis is any unpleasant odor emerging from the mouth that is detected by others. Many patients experience extreme discomfort and embarrassment and therefore seek help for this problem. Oral causes, such as poor oral hygiene, periodontal disease, tongue coating, food impaction, unclean dentures, faulty restorations, and dry mouth, are far more common than nonoral causes of malodor. Management may include simple measures such as scaling and root planing, instructions in oral hygiene, tongue cleaning, and mouth rinsing. This paper reviews the current knowledge, etiology, diagnosis, and possible treatment strategies for oral malodor. Emphasis is placed on the recognition of the dental hygienist as a specialist in aspects of patient care and instruction, which relate to the prevention and control of oral malodor.

Breath Tests↗