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At least 541 records · Page 30Linked to original sources
PubMed1990

Intra-aortic balloon counterpulsation as a therapy for shock.

As early as 1967, IABC has been effectively used to support patients in cardiogenic shock. IABC provides the temporary circulatory assistance necessary to maintain coronary perfusion pressure, improve stroke volume and cardiac output, and decrease left ventricular preload and afterload. Until new forward flow devices are perfected and become globally available as mechanical assistance for pump failure, the intra-aortic balloon pump will continue to provide temporary mechanical circulatory assistance to support patients in cardiogenic shock until diagnosis of the underlying cause and definitive therapy can be determined.

Counterpulsation↗
PubMed1990

Perioperative intra-aortic balloon counterpulsation in cardiosurgery: a retrospective study.

From January 1986 to March 1988 50 of 1366 patients (3.7%) undergoing cardiac surgery were treated with IABP support. The 50 patients ranged in age from 43 to 79 years (mean: 63.3 years). 88% of them underwent coronary artery bypass grafting, 6% of them mitral valve replacement and the other 6% a combined procedure. IABP was inserted preoperatively in 4 patients (8%) because of cardiogenic shock, and in 18 patients because of unstable angina (36%); intraoperatively as a help during weaning from cardiopulmonary bypass in 8 patients (16%); postoperatively because of hemodynamic deterioration in 20 patients (40%). The IABP was placed by femoral puncture in 39 patients (78%), by femoral cutdown in 6 patients (12%) and by transthoracic aortotomy in 5 patients (10%). All patients received daily infusions of heparin and broad spectrum antibiotics. The overall incidence of complications was 22%. There was no mortality due to IABP-related complications.

Adult↗
PubMed1994

Study of the external counterpulsation (ECP) therapy for senile dementia of the Alzheimer's type (SDAT).

Ten patients with SDAT received the ECP therapy. The examination of Hasegawa's Dementia Scale (HDS), single photor emission computed tomography (SPECT) brain imaging, and some biochemical parameters in blood and CSF were selected to evaluate the effect of ECP for SDAT. After ECP treatment, the average HDS score of the patients increased, the value of P was close to 0.05; and the cortical cerebellar ratios of SPECT brain scan, the superoxide dismutase (SOD) activity and the concentrations of somatostatin-like immunoreactivity (SLI), dynorphin AL-13 (Dyn Al-13) in blood and/or CSF were significantly elevated. The results indicated that ECP could not only improve cerebral blood flow, but also make a notable impact on biological active substances in blood and CSF. It is suggested that ECP is beneficial to SDAT patients.

Aged↗
PubMedDate not supplied

Experimental study of combination of extraaortic balloon counterpulsation and ventricular assist cup to acute heart failure in dogs.

The goal of this study is to evaluate the applicability and effectiveness of combination support of the extraaortic balloon (EAB) and the ventricular assist cup (VAC) to the acute heart failure model. Under general anesthesia, 10 adult dogs were used. Through the median sternotomy, EAB was placed around the ascending aorta and VAC in the pericardial cavity. After heart failure was induced by administration of propranolol, the on-off tests of devices were done as follows. Only EAB was used, and only VAC was used and both devices were used. Regional blood flows (RBFs) of both ventricles, liver kidneys, and brain were measured by colored microsphere technique. Hemodynamic parameters were also measured. In heart failure model, cardiac output (CO) decreased to 66% of control value. In the group assisted by EAB, aortic peak-diastolic pressure and RBFs of both ventricle and brain increased significantly. In the group assisted by VAC, CO and RBFs of all but the left ventricle significantly increased. In the group assisted by EAB and VAC, aortic peak-diastolic pressure, CO, and all five RBFs significantly increased. These results suggest the combination of EAB and VAC is applicable and effective and would be a promising implantable device for the chronic heart failure.

Acute Disease↗