PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “INFECTIOUS ABORTION”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 541 records · Page 30Linked to original sources
PubMedDate not supplied

[Monitoring of pregnancy in HIV seropositive women].

The management of pregnancy in a seropositive woman implies awareness of the effects of the disease on pregnancy and, inversely, of the pregnancy on HIV infection. It is important to be aware of the risk of materno-fetal transmission, as well as of the recent positive results of therapeutic trials of AZT during pregnancy regarding the prevention of such transmission. This quite stereotyped management approach is relatively simple, both clinically and regarding laboratory investigations, and in particular when the patient is at an asymptomatic stage of the disease. Obstetric management is, for the present, the same as in normal women. It is important to stress the need for specialised management of the newborn infant and of taking advantage of the postpartum period to ensure future effective contraception.

Abortion, Therapeutic↗
PubMed1993

Pregnancy outcomes following systemic prenatal acyclovir exposure--June 1, 1984-June 30, 1993.

Herpes infections are common among women of reproductive age (i.e., aged 15-44 years). Acyclovir (Zovirax), an antiviral drug effective in the treatment of herpes simplex infection, was approved by the Food and Drug Administration (FDA) in 1984. Since its approval, the effects of acyclovir on human pregnancies have not been determined. However, inadvertent pregnancy exposures to acyclovir were expected to occur among women in whom treatment had been indicated for preexisting herpes simplex infections. Some physicians have reported intentional use of acyclovir during pregnancy for treatment of life-threatening herpes simplex infection. To assess the outcomes of pregnancies exposed to acyclovir, the Acyclovir in Pregnancy Registry was established on June 1, 1984, by the manufacturer, in collaboration with CDC. This report summarizes data on pregnancies reported to the registry through June 30, 1993.

Abnormalities, Drug-Induced↗
PubMed1978

[Isolation of adenovirus type 1 from aborted cattle fetuses].

Five adenoviral strains, typed as adenovirus type 1, were isolated from aborted cattle foetuses, taken from farms with abortions in cows. The viruses were isolated from kidneys, lungs and livers of the foetuses. They were isolated from the kidney most frequenty (three strains). Intranuclear basophilic inclusions in the alveolar epithelium of the lungs and in the tubular epithelium of the kidneys have been established in the histological investigations of the internal organs of the foetuses. The isolation of adenoviruses from foetuses has been discussed as an infectious process, emerging as a result of a transplacental infection.

Abortion, Veterinary↗
PubMed2005

Pregnancy diagnosis and abnormalities of pregnancy in the dog.

New and traditional techniques for pregnancy diagnosis in the dog are reviewed. Imaging techniques yield the most information, with ultrasonography the preferred technique for assessment of fetal viability and radiography the preferred technique for assessment of litter size. Diabetes mellitus and pregnancy toxemia are uncommon complications of pregnancy. Pathogenesis, diagnosis and treatment of infectious and non-infectious causes of pregnancy loss are reviewed.

Abortion, Veterinary↗
PubMed2003

Chorioamnionitis caused by Serratia marcescens in a non-immunocompromised host.

A 26 year old pregnant woman with antithrombin III deficiency developed recurrent septicaemia with Serratia marcescens. In spite of the administration of antibiotics, high grade fever persisted. She subsequently manifested lower abdominal pain, and spontaneous abortion occurred. After the abortion, she became completely afebrile. The amnion was turbid, and microscopic examination of the placenta showed haemorrhage and massive infiltration of neutrophils, suggestive of infectious chorioamnionitis. Pulsed field gel electrophoresis showed that isolates from the blood, urine, and vaginal discharge were genetically identical. Intravenous pyelography revealed that she had a bilateral completed double ureter. It was thought that a urinary tract anomaly caused infection with S marcescens, and the pathogen spread to the chorioamnion via the bloodstream. This is the first report of chorioamnionitis caused by S marcescens in a non-immunocompromised host. In addition, these findings indicate that the chorioamnion can serve as a site for persistent infection in normal pregnancies.

Abortion, Spontaneous↗
PubMed1989

[Mycoplasma infections in farm animals: specific prevention of infectious (contagious) agalactia in the sheep and goat].

The authors of this paper have produced live vaccine to cope with infectious agalactia in goat. The vaccine (culture) was used on 360, 924 goats kept on ajmaks in Bajanchongor and Gobi-Altaj, in 1986. The number of pathologically affected goats went down by a factor of 4.5, as compared to 1985. Mortality was reduced to one third. Abortions declined by a factor of 2.6 and infertility among goats by 1.6. The conclusion is that sheep of the Mongolian breed are not susceptible to infectious agalactia. Large-scale production tests of live cultures supported hopes for successful action on this infectious disease under Mongolian conditions.

Animals↗
PubMed1977

Experimental and naturally occurring transplacental transmission of canine distemper virus.

In the present study, 2 different effects of experimentally induced infection with virulent canine distemper virus (CDV) on pregnant CDV-susceptible dogs were studied. In 1 bitch, abortion occurred 7 days after viral inoculation and there was no evidence of fetal infection. Another bitch had subclinical infection and delivered 3 CDV-infected pups. Sequential clinical, immunologic, and virologic studies of a litter of gnotobiotic pups (3rd bitch) that were congenitally infected with CDV demonstrated the heightened susceptibility to CDV in the neonatal period. The data presented add canine distemper to the list of transplacental infectious diseases in the canine species.

Abortion, Veterinary↗
PubMed1994

Microbiology relevant to recurrent miscarriage.

The best evidence suggests that infection is an occasional cause of sporadic spontaneous abortion, and, consistent with statistical probability, recurrent miscarriage due to infection occurs with a frequency that is much lower. In the medical literature, the limited evidence linking infection and recurrent pregnancy loss in humans remains largely anecdotal and generally cannot be reproduced in prospective studies. This observation reflects the low frequency with which the necessary microbial and maternal factors combine to cause recurrent miscarriage. The patient's susceptibility to chronic infection must play a determining role in some of the reported cases. Susceptibility factors that allow severe chronic infection, such as immunocompromise, are rare in the general infertility population and may remain unrecognized in broad cumulative studies. Probable factors that play a role in the risk of abortion due to infection are the following: 1. Primary exposure during early gestation 2. The capability of the organism to cause placental infection 3. The development of an infectious carrier state 4. Immunocompromise caused by immunosuppressants, chemotherapy, corticosteroids, or acquired immune deficiency syndrome. Exposure to a microbe that can establish chronic infection that can spread to the placenta in an immunocompromised patient is probably the most obvious risk situation for habitual abortion. In routine medical practice, it is not necessary or efficient to screen universally for the unexpected, but it is necessary to be aware of the rare possibilities. Most patients with a history of recurrent miscarriage will not benefit from an extensive infection workup. All patients should first be categorized according to their own personal risk infection, as outlined in Table 2.(ABSTRACT TRUNCATED AT 250 WORDS)

Abortion, Habitual↗
PubMed1990

Interaction of African swine fever virus with macrophages.

Morphological data obtained by electron microscopy have shown that African swine fever virus adapted to VERO cells enters swine macrophages, its natural host cell, by a mechanism of receptor-mediated endocytosis. Binding studies with 3H-labeled virus and competition experiments with UV-inactivated virus have shown that the virus entry that leads to a productive infection in swine macrophages is mediated by saturable binding sites on the plasma membrane. The virus also penetrated into rabbit macrophages that do not produce infectious virus and initiated the synthesis of some early viral proteins; however, the viral replication cycle was aborted since viral DNA synthesis did not occur. The interaction of ASF virus particles with rabbit macrophages was mediated by nonsaturable binding sites, suggesting that the lack of specific receptors in these cells may be related to the absence of a productive infection. A similar abortive infection was detected in macrophages from other virus-resistant animal species.

African Swine Fever Virus↗
PubMed2002

Seroprevalence of antibodies against Neospora caninum in diagnostic equine serum samples and their possible association with fetal loss.

A case-control study of the association between the presence of serum antibodies against Neospora spp. and fetal loss was performed on serum samples submitted to a veterinary diagnostic laboratory in northwestern United States. Control sera were randomly selected from those submitted from healthy horses for routine equine infectious anemia testing required for regulatory health certification. Case sera were randomly selected from those submitted from aborting mares for diagnostic workup. Based on a 1:50 or greater titer on the indirect fluorescent antibody test, 8% of the 160 control sera and 13% of the 140 case sera were titer positive. The association odds ratio of 1.67 fell short of statistical significance (p=0.124).

Abortion, Veterinary↗
PubMed1975

Post-transcriptional restriction of human adenovirus expression in monkey cells.

Infection of the continuous simian cell lines CV-1 and BSC-1 with human adenovirus type 2 (Ad2) is abortive. However, the restriction of Ad2 reproduction in these cells can be overcome by increasing the Ad2 infectious dose or by coinfection with simian virus 40. Vero, another established simian cell line free of detectable endogenous simian virus 40 DNA, is not restricted in its ability to promote Ad2 growth even at low input multiplicities of Ad2 and in the absence of SV40 helper. The amount of structural Ad2 proteins in total cell extracts of enhanced BSC-1 cells is at least two orders of magnitude higher than that of unenhanced cells. In contrast, comparable quantities of Ad2 mRNA specifying these proteins are found in both the enhanced and the unenhanced cell. Both sets of mRNA can be translated in a cell-free system with equal efficiency.

Adenoviridae↗