Systemic and inhalation therapy with cortisone--a brief introduction.
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Data are presented on the relationships between air flow rates and pressures generated by 15 brands of domiciliary compressor currently used in the United Kingdom to drive jet nebulisers. Since compressor brands vary widely in power, care must be taken in the selection of appropriate models for efficient respiratory therapy.
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The Authors studied the behaviour of lung volumes and mechanics and of haematocrit after intermittent pulmonary positive pressure breathing (IPPB) in patients with chronic obstructive lung disease. An improvement of obstructive sindrome at 10'-20'-40' and a contemporary decreasing of haematocrit were observed. This statistically significant modification was regarded as an expression of a different distribution of blood in lung vessels dued to an increasing of this vascular compliance and to a decrease of alveolar inflation. The Authors postulate the realization of a better circulation in lung vessels which contributes to a lowering of haematocrit in these patients perhaps for a different VA/Ob ratio.
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The various techniques for aerosol therapy are described, as applied to inflammations of the upper and lower airways. Advances in treatment include dinatrium cromoglicicum and beclomethasone-dipropionate, with the latter medication improving results in patients with allergic reactions of the nasal and bronchial mucosa.
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