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[Clinical aspects and pathology of chondromatous tumors of the larynx].

Two cases of chondroma of the larynx are presented: After the first laryngofissure and excision both tumours recurred so that several operations became necessary. A transformation from chondroma to chondrosarcoma was observed based on repeated histological examinations. In the first patient pulmonary metastases and a recurrence at the tracheostomy appeared 11 years after presentation and 41/2 years after laryngectomy. In the other female patient no obvious signs of the neoplasm are present 9 years after presentation, and 4 months after the last operation for recurrence, but the prognosis remains undetermined. 101 cases of chondrosarcoma from the literature plus our 2 observations are listed and compared with 130 chondrosarcomas of the skeleton. Contrary to previous opinions, we conclude that chondrosarcoma of the larynx behaves in the same malignant manner as those of the skeleton. Some develop metastases quickly, others only after years and after at least one operation for recurrence. We could demonstrate that a detailed histological examination allows the prognosis to be assessed. Additional risk factors were also investigated. These two cases enable a better and more reliable judgement to be made of the prospective biological behaviour of chondromatous tumours of the larynx and at an earlier period of time of the process.

Aged↗

Functional anatomy of the larynx.

The larynx should be thought of as a sphincteric valve mechanism in the neck. It is composed of a relatively rigid skeleton and an inner lining, which passively is displayed as a series of elastic folds. These folds are anchored superiorly to the skull base and inferiorly to the trachea. Active folding and unfolding are accomplished by external and internal muscle activity to meet the various functional demands placed upon the larynx.

Adult↗

Malignant degeneration of a juvenile laryngeal papilloma--a follow-up study.

The patient, a non-smoking woman aged 51, had been suffering from recurrent juvenile papilloma for 38 years. After eight years during which there was increasing atypia, an extensive malignant papillary tumor, with extralaryngeal spread, was diagnosed. Only seven cases of malignant degeneration of non-irradiated juvenile laryngeal papilloma have been reported; at least four were heavy smokers.

Carcinoma, Squamous Cell↗

Spiral CT of the larynx.

PURPOSE: To compare conventional and spiral CT studies of the larynx. METHODS: Ten patients had both conventional and spiral CT studies of the neck using 5-mm section collimation and 5-mm increments. The spiral scans also were reconstructed at 2-mm increments. Five patients had two spiral CT larynx studies with 5-mm and 2-mm collimation. Two observers independently rated the visibility of laryngeal structures and absence of motion artifact in the studies and assigned values from 1 (poor) to 4 (excellent). RESULTS: The spiral scan images showed less motion artifact (1.9 versus 3.6) and better anatomic detail (2.3 versus approximately 2.6). Thinner reconstruction intervals and sections gave better anatomic detail (2.3 versus approximately 3.3). Interobserver kappa was 0.65. CONCLUSION: Spiral is better than conventional CT scanning when studying the larynx.

Adult↗