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Inhibition by nifedipine of the efflux of plasma low-density lipoprotein and albumin from the vasculature of the mouse mesentery in vivo.

Efflux and extravascular accumulation of intravenously administered fluorescent-labeled low-density lipoprotein (LDL) and albumin were measured in superfused mouse mesenteric preparation in anesthetized mice. Pretreatment of animals with nifedipine (1 and 3 mg/kg sc) significantly reduced both the extravascular accumulation of LDL (measured by fluorescence densitometry) and the efflux (measurement of the tracers in the superfusate) of both LDL and albumin. These effects may help to explain the possible anti-atherogenic effect of nifedipine.

Animals↗

Chylous cyst of the mesentery: US and CT diagnosis.

We report a case of mesenteric chylous cyst diagnosed preoperatively by ultrasonography (US) and computed tomography (CT). Both demonstrated a unilocular cystic mass with a fluid-fluid level. The CT number of the two components indicated fat density and water density and with shaking or positional changes, the contents displayed miscibility. The tumor changed its position during hospitalization. Both features are considered to be quite diagnostic of this condition.

Chyle↗

Homicidal blunt abdominal trauma with isolated laceration of the small bowel mesentery.

Nonpenetrating abdominal trauma rarely causes isolated mesenteric lacerations with fatal hemorrhages. When this does happen, it is often the result of compression by a lap seal belt or a steering wheel, only extremely rarely is it the result of a homicidal act. In the present paper, two homicide victims with resulting mesenteric tears and fatal bleeding due to sagittal compression are described. A high blood alcohol concentration may in both cases have contributed to the fatal outcome. The cases support the assumption that direct rather than indirect trauma causes this kind of lesion.

Abdominal Injuries↗

Suggestive evidence for a functional unit between mast cells and substance P fibers in the rat diaphragm and mesentery.

A close spatial relationship between serotonin-containing mast cells and substance P-containing nerves was shown by immunohistochemistry using a combination of antisera specific for serotonin and substance P. This supports earlier morphological results suggesting an innervation of mast cells and pharmacological studies which postulate an influence of substance P on the release of histamine from mast cells.

Animals↗