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Reflex cervical muscle spasm: treatment by diazepam, phenobarbital or placebo.

This double-blind study of the effects of diazepam on painful cervical muscle spasms compared with those of phenobarbital and an inert placebo employed clinical, electrogoniometric and electromyographic recording methods for evaluation and computer analysis. The clinical results were equivocal but the technological recordings revealed a statistically significant greater desirable effect of diazepam compared to the other 2 treatments which would be expected to have only minor nonspecific effects.

Adult↗

Therapeutic traction: a review of neurological principles and clinical applications.

A brief review of traction and its application as a therapeutic tool is outlined. The preliminary results obtained indicate that traction, as used in this study, along with isokinetic exercises and chiropractic manipulation, have a very positive effect on tension headaches originating from the posterior muscles in conjunction with pathomechanics of the cervical spine. A brief but pertinent review of the literature dealing with the anatomy and physiology of the muscle spindle, the muscles, the joints, the neural connections in the spinal cord and the central nervous system is presented, to provide the basic principles of the possible mechanisms underlying the therapeutic result obtained. This framework also provides the basis of a second paper, which will explore the neural control mechanisms that are intrinsic in the control of the head, eyes and cervical spine movement, with the view of utilizing these to facilitate manipulation of this region.

Adult↗

The mechanisms of bronchospasm in experimental microbial sensitization. I. Immunological stage.

Immune mechanisms of smooth muscle spastic bronchial reactions were reproduced and studied in isolated guinea pig lungs and found to develop type I, III and IV allergic reactions at sensitization to brucella and staphylococcus. Type I reactions were reproduced in animal lungs with immediate hypersensitivity to soluble microbial antigens. Type III reactions were obtained by transfusion of soluble immune complexes containing microbial antigens into isolated lungs Bronchospastic reactions arose only in the presence of the complement. Antibodies responsible for bronchospasm belonged to the IgG class. Type IV reactions were produced in vitro using supernatants obtained by incubation of lymphoid cells isolated from animals with delayed hypersensitivity with homologic microbial antigens. The supernatants possessed bronchospastic action.

Allergens↗