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Results for “Retinal Detachment”

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PubMed1975

Glial cell proliferation in retinal detachment (massive periretinal proliferation).

In experimental retinal detachment of the owl monkey we observed the formation of preretinal and subretinal membranes which had cellular connections to the retina proper. Based on light microscopic findings we concluded that retinal cells grow out of the retina and build up the preretinal and subretinal tissue. Electron microscopically these cells are identified as astrocytes which grow out through focal interruptions in the internal or external limiting membrane. In the immediate area of outgrowth Muller cell processes praticipate in the formation of the preretinal or subretinal tissue. These glial membranes can cause wrinkling of the internal limiting membrane and the nerve fiber layer or full-thickness folding of the retina. Glial proliferation plays an important role in the development of a complication in retinal detachment which we suggest calling "massive periretinal proliferation" (MPP).

Animals↗

PubMed1998

Crystalline retinopathy associated with chronic retinal detachment.

OBJECTIVE: To describe the presence of crystalline opacities located at the level of the inner retina in patients with chronic retinal detachment. METHODS: We reviewed the clinical records, fundus photographs, and fluorescein angiograms of patients with superficial retinal crystals in the presence of a chronic retinal detachment. RESULTS: Eleven eyes in 11 patients with chronic retinal detachment were found to have these peculiar crystalline opacities on the inner retinal surface. In 5 patients, the crystalline opacities were noted on initial assessment prior to surgery and persisted without change in appearance or number after surgical repair. In 6 eyes, the crystals were not appreciated until after surgical repair of the retinal detachment. The crystals appeared similar in all 11 eyes, were highly refractile, and were located in the posterior pole. Eight of the eyes had retinal detachment associated with retinal dialysis and 6 of these had a history of trauma. There was a definite history of vitreous hemorrhage in 2 eyes. The crystals did not seem to be associated with any visual deficit. CONCLUSIONS: Chronic retinal detachment can be associated with crystals on the inner retinal surface. The cause and composition of these crystals are unknown. They seem to be visually inconsequential and unchanging.

Adult↗

PubMed2006

Fellow eye of patients with retinal detachment associated with macular hole and bilateral high myopia.

PURPOSE: To estimate the risk of retinal detachment in the fellow eye of patients with bilateral high myopia who had retinal detachment associated with macular hole (MH-RD) in one eye. METHODS: The present study examined retrospectively 56 patients with bilateral high myopia who had MH-RD. To determine the incidence of involvement of the fellow eye, patients who completed a follow up of 12 months or longer were eligible for the current study. RESULTS: Of 56 patients with MH-RD due to high myopia, 54 had unilateral detachment at presentation and two had bilateral detachment. Of the 54 highly myopic fellow eyes without retinal detachment at presentation, 37 eyes underwent 12 or more months of documented follow up. Mean follow up after initial surgery to the primary eye was 6.5 +/- 4.9 years. During follow up, a macular hole without retinal detachment was noted in one (2.7%) of these 37 eyes. Three other eyes (8.1%) had MH-RD at 1, 2 and 7 years, respectively, after the initial surgery to the primary eye. At the final visit, 12 eyes (32%) had visual acuity of > or =6/9, whereas 12 eyes (32%) had visual acuity of < or =6/60. CONCLUSIONS: When patients with bilateral high myopia have MH-RD in one eye, they would be expected to be at increased risk of retinal detachment in the fellow eye.

Aged↗

PubMed1987

Hereditary X-linked retinoschisis and bilateral congenital retinal detachment.

Differential diagnosis and histopathological findings of bilateral congenital retinal detachment in a 10-month-old boy are presented. By ultrasonography, the presence of bilateral retinoblastoma was suspected. Histopathological examination of the more seriously affected eye revealed retrolental mass composed of tightly packed retinal folds fused together by fibrovascular tissue. The retina was partly disorganized, with the ganglion cells scanty or missing. Large retinoschisis cysts were not found, but areas of splitting in the inner retina were present. Examination of the family members disclosed congenital retinoschisis in the maternal grandfather and his two brothers. These findings indicate that the most probable etiology of bilateral congenital retinal detachment of the patient was hereditary X-linked retinoschisis. Surgery for retinal detachment of the fellow eye was not successful.

Genetic Linkage↗

PubMed1995

Retinal detachment in association with preeclampsia and abruptio placentae.

Retinal detachment is a rare complication of preeclampsia, eclampsia and abruptio placentae. We report a case of bilateral retinal detachment in association with severe preeclampsia complicated with abruptio placentae, intrauterine fetal death and disseminated intravascular coagulation. In obstetric complications, placental thromboplastin may release into maternal circulation and activate the extrinsic coagulation system with resultant disseminated intravascular coagulation. This may be responsible for choroidal ischemia and consequent serous retinal detachment.

Abruptio Placentae↗

PubMed1998

Iris retraction syndrome associated with nonrhegmatogenous retinal detachment.

PURPOSE: To present the first documentation of iris retraction syndrome in eyes with nonrhegmatogenous retinal detachment. PATIENTS AND METHODS: One patient with age-related macular degeneration and another with panuveitis developed exudative retinal detachment with iris retraction configuration. Ultrasound biomicroscopy was performed to investigate the anatomic relationship of structures in the anterior segment of the eye. RESULTS: Ultrasound biomicroscopy demonstrated a severe backward bowing of the peripheral iris with irido-ciliary body and irido-zonular contact as well as broad iris lens touch. The iris retraction syndrome resolved after pupil dilation and disruption of the pupillary adhesions in both cases. The retinal detachment resolved several months later, without surgery. CONCLUSION: Iris retraction syndrome appears not to be exclusive to rhegmatogenous retinal detachment but can present in eyes with exudative - nonrhegmatogenous retinal detachment. Thus, when the configuration of the iris shows bowing in patients with retinal detachment, iris retraction syndrome should be considered and prompt pupil dilation should be carried out.

Aged↗

PubMed1981

Retinal detachments following intraocular lens implantation.

Pseudophakic retinal detachments are more difficult to manage than the phakic variety, primarily because of increased difficulties in visualizing the peripheral retina. A review of the characteristics of 70 pseudophakic retinal detachments revealed that they were similar to those following routine cataract extraction, although we noted a mild tendency for periretinal membrane formation to be more commonly associated with the former group. Despite problems in viewing pseudophakic detachments, our data suggest that their repair rate closely approximates that for aphakic eyes, assuming allowances are made for the number of cases with significant periretinal membranes that are accepted for surgery. Visual results following successful surgery may be somewhat lower than those in comparable aphakic eyes.

Aged↗

PubMed1985

Juvenile vitreoretinal degeneration and retinal detachment.

The proband was a 10-year-old boy with bilateral retinal detachment. His mother had unilateral retinal detachment at age of 12. The eye disease occurred in eight family members, both men and women, in four consecutive generations suggesting autosomal dominant inheritance. The eye findings were seen at the age of 4 to 12 and included syneresis and posterior vitreous detachment; spotty areas of whitish, glistening degeneration, spotty hyperpigmentation, and greyish-white patches with pigmentations suggestive of healed retinochoroiditis in the peripheral retina. Retinal detachment with holes in the peripheral retina occurred in four family members, and three other family members had unilateral blindness since early childhood. In eyes without retinal detachment the visual acuity, visual fields, dark adaptation, and colour vision were normal.

Adult↗

PubMed1998

[Characteristics of retinal detachment in eyes with choroidal colobomas].

We reviewed 6 eyes of 6 patients (1 male and 5 females) with retinal detachment associated with choroidal coloboma. Three of these 6 eyes had visible retinal breaks within or at the margin of the coloboma. In one eye, no retinal breaks were noted before or during vitreous surgery, and shallow retinal detachment was localized in the posterior fundus. One eye with bullous retinal detachment with retinal breaks within the coloboma had been having serous retinal detachment localized in the nasal area close to the optic nerve head. In all of these five eyes; vitrectomy, relaxing retinotomy inside the coloboma close to its edges, and cyanoacrylate retinopexy resulted in successful reattachment of the retina. Schisis-like separation similar to that in pit-macular syndrome was noted in the posterior retinal in one eye which had no visible retinal break. Non-rhegmatogenous retinal detachment may exist in association with choroidal colobomas.

Adolescent↗

PubMed1997

Retinal detachment following excimer laser.

AIM: To report the clinical presentation, surgical management, and outcome of retinal detachment following excimer laser. METHODS: Retrospective analysis of retinal detachments observed in 11 eyes of 10 myopic patients who had previously undergone photorefractive keratectomy (PRK) or phototherapeutic keratectomy (PTK) by excimer laser. RESULTS: Symptoms of visual loss in two eyes were initially attributed to corneal haze. In 10 of 11 eyes visualisation of the retinal detachment and causative break was possible despite mild corneal haze and optical aberrations caused by the refractive laser procedure. Retinal reattachment was achieved in all 11 eyes though one eye required four surgical interventions. CONCLUSION: This is the first published report to describe an association between retinal detachment and previous excimer laser treatment. The association would appear to reflect the predisposition of myopes to retinal detachment. Clinicians should be aware of potential retinal pathology in patients undergoing PRK.

Adult↗

PubMed1995

[Vitrectomy combined with scleral buckling for the treatment of complicated retinal detachment].

PURPOSE: To raise operative successful rate of complicated retinal detachment, we used the methods of vitrectomy combined with scleral buckling for the treatment of complicated retinal detachment. METHODS: The operative methods included: scleral buckling, vitrectomy, membrane peeling, intraocular and extraocular drainage, gas and silicone oil tamponade. RESULT: Being followed up for 1-16 months, 22 eyes got anatomic reattachment in 29 eyes, the operative successful rate was 75.8%; 15 eyes were injected with silicone oil intraocular tamponade, with 12 eyes getting reattachment. The successful rate was 80%. CONCLUSION: Since the vitreous surgery is used, it is possible for the treatment of complicated retinal detachment, the operative successful rate can be raised. The technique of membrane peeling and intraocular tamponade was very important. Silicone oil has been accepted by more and more ophthalologists in the world, which acts as an effective material of intraocular tamponade.

Adolescent↗

PubMed2004

Retinal detachment of regressed retinopathy of prematurity in children aged 2 to 15 years.

PURPOSE: To reveal the clinical features and surgical results of retinal detachment of regressed retinopathy of prematurity (ROP) that occur in the children aged 2 to 15 years. PATIENTS AND METHODS: The records of patient who had a retinal detachment of a regressed ROP were retrospectively reviewed. Sixteen eyes from 15 patients that required surgical treatments due to retinal detachment of a regressed ROP were included. RESULTS: After treatment of acute phase of ROP, eight eyes showed grade II of cicatricial change and eight eyes showed grade III. We did not find any evidence that the acute stages of ROP and its treatment affect the degree of the cicatricial changes. All eight eyes with grade III of cicatricial ROP showed tractional retinal detachment (TRD) and five of eight eyes (62.5%) with grade II showed rhegmatogenous retinal detachment (RRD). The mean interval between regressed ROP and development of late retinal detachment was 20.7 months (range, 12-61 months) in the TRD group and 85.8 months (range, 33-148) in the RRD group. The mean age at onset of late detachment was 34.1 months (range, 26-73 months) in the TRD group and 98.6 months (range, 45-162) in the RRD group. Anatomical success was achieved at one of five eyes (20%) with RRD and six of 11 eyes (54.5%) with TRD. Compared with the preoperative visual acuity, visual improvement, no change, and decreased visual acuity were achieved, respectively, in two eyes, three eyes, and no eyes in the RRD group and three eyes, six eyes, and two eyes in the TRD group. However, only two of 16 eyes with late retinal detachment achieved a visual acuity of 20/200 or better. CONCLUSION: Late retinal detachment is the main vision-threatening condition in patients with regressed ROP during childhood. The visual prognoses of these patients are poorer than those with late retinal detachments that occur in adult ROP patients. Therefore, a periodic fundus examination should be performed more frequently during childhood than in adulthood, particularly in nonverbal children.

Acute Disease↗

PubMed2005

Retinal detachment in south India-presentation and treatment outcomes.

BACKGROUND: Although the presentation and treatment outcomes of retinal detachments in wealthy countries are well known, much less is known about retinal detachment in the developing world. This study reports the presentation and outcomes of 433 rhegmatogenous retinal detachments in South India. METHODS: Retrospective analysis was undertaken of all operated cases of retinal detachment in a tertiary care centre, from 1 January 2000 to 31 December 2000. RESULTS: Retinal detachments were treated in 433 eyes of 417 patients; 67 (16.1%) patients were children below 16 years and 60 (14.4%) patients were blind (visual acuity <6/60). The duration of symptoms was over 1 month in 192 (46.6%) eyes and, in 376 (86.8%), the macula was detached at presentation. Referral diagnosis was incorrect in 69 (22.4%) eyes. Cataract surgery was the predisposing factor in 152 (35.1%) eyes. Primary surgery included pars plana vitrectomy procedures in 235 eyes (53.9%) and scleral buckling in 197 (45.8%). The retina was re-attached with one operation in 281 eyes (71%) and with one or more operations in 333 (87%). Visual acuity of 6/60 or better was achieved in 260 (67.7%) eyes. CONCLUSIONS: The profile of retinal detachments in a tertiary eye care centre in south India includes many paediatric cases, late presentations and macula-off detachments, commonly related to cataract surgery. Despite complex pathology, two thirds of eyes regain useful vision after one or more surgical interventions.

Adolescent↗

PubMedDate not supplied

Surgical management of retinal detachment with choroidal coloboma.

PURPOSE: To verify the functional and anatomical results of retinal detachments related to choroidal coloboma. METHODS: Seven eyes with retinal detachment secondary to retinal breaks at the margin of or within a choroidal coloboma were analysed retrospectively. RESULTS: Scleral buckling was performed in five of the seven eyes; two needed additional pars plana vitrectomy (PPV) with internal tamponade using silicone oil to reattach the retina. In two eyes PPV with internal tamponade using silicone oil or gas was used as a primary procedure. All seven eyes were reattached. Five eyes (71.4%) showed improvement or had visual acuity of 20/400 or better after surgery, but two remained unchanged. CONCLUSIONS: Retinal detachment secondary to choroidal coloboma can be treated successfully by scleral buckling or PPV with internal tamponade.

Adult↗

PubMed1989

[Retinal detachment associated with coloboma of choroid].

Retinal detachment associated with congenital coloboma of choroid is an unusual type of the disease 32 cases (34 eyes), or 1.23% of all 2,602 cases of retinal detachment, were operated on during 1980 to 1986. 17 (53%) patients were under 20 years of age and 28(88%) under 30 years. Preoperative visual acuities ranged from light perception to 0.2, and 25 eyes(74%) under 0.05. The associated congenital abnormalities were coloboma of iris in 32 eyes(94%), cataract in 25(74%), microcornea in 17(50%), and nystagmus in 13(38%). The detection of breaks in the rudimentary retina was extremely difficult, with a positive rate of only 56%, and immediate operative success was obtained in 18 eyes(53%), which were followed up for an average 36 months with re-detachment in 5 eyes. The rate of long term operative success was 38%. With the choroidal coloboma below the optic disc, the retinal breaks outside of the coloboma or in the coloboma near the edge, or the detachment involving at most 3 quadrants of the fundus, the rates of operative success were 81%, 70%, and 100% respectively.

Adolescent↗

PubMed1985

Experimental retinal detachment. X. Effect of acetazolamide on vitreous fluorescein disappearance.

Retinal detachments were created in one eye of each of eight cynomolgus monkeys. Total vitrectomy was performed in the fellow eyes. Fluorophotometry was used to study the rate of disappearance of fluorescein injected into the vitreous cavity. The rate of fluorescein loss via the anterior chamber accounted for only 1% to 3% of the total rate of vitreous fluorescein loss in eyes with retinal detachment or in fellow eyes. Posterior loss of fluorescein (presumably across the retinal pigment epithelium) increased by 25% following intravenous acetazolamide in eyes with retinal detachment and 22% in fellow eyes. It is concluded that acetazolamide increases the rate of fluid absorption across the retinal pigment epithelium.

Acetazolamide↗

PubMed1998

[The clinical features of retinal detachment with congenital choroidal coloboma].

OBJECTIVE: To approach the clinical features of retinal detachment with congenital choroidal coloboma and seek better surgical methods to improve the effect of treatment. METHODS: Vitreoretinal surgery was performed on eight patients of retinal detachment with choroidal coloboma. During surgery by using an operating microscope with high magnification and endoillumination, we searched for retinal break(s) located in the colobomatous area, looked into the condition of posterior hyaloid area, status of coloboma, treatment was given accordingly, and finally silicone oil tamponade was performed. RESULTS: Retina was reattached anatomically after operation in all cases, and their visual acuities improved. CONCLUSIONS: The type of retinal detachment is caused by the retinal break inside the coloboma. The breaks located at the edge of the detachment within the coloboma, ectatic sclera at the colobomatous region, without posterior vitreous detachment are the features of the retinal detachment with congenital choroidal coloboma. Complete vitrectomy with method to create chorioretinal adhesion around the coloboma and silicone oil tamponade provide an effective treatment for this complicated type of retinal detachment.

Adolescent↗

PubMed2000

[The clinical aspects in myopic retinal detachment].

UNLABELLED: Beside aphakia and senility myopia is one of the major factors predisposing to retinal detachment. The purpose of the study is to define the clinical features of the myopic retinal detachment with therapeutic and prognostic implications. METHOD: 100 myopic (< 6 dioptres) retinal detachments that were hospitalized in the Ophthalmological Department from Cluj-Napoca between 1996-99 are retrospectively analyzed. RESULTS, DISCUSSION: The major clinical elements having an impact in defining the anatomical and functional prognosis of the myopic retinal detachment are described and analyzed: the extension of the retinal detachment, the number and shape of the retinal ruptures, the detachment of the macula, the association of aphakia and of myopic choroidosis.

Adult↗