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PubMed1986

[Population-genetical study of differential fertility in humans (based on an example of habitual abortion). I. Approach to the problem and analysis of morpho-physiological and demographic traits].

It was shown that women from the studied group of married couples, suffering from repeated spontaneous abortions (the main group), have earlier menarche and their husbands are taller, as compared with the control group of couples with normal reproductive performance. The degree of similarity between mates in age and stature appeared to be lower in the main group than in the control group. The variation of the characters under study is supposed to provide an auxiliary criterion in selecting couples at high risk of repeated spontaneous abortions.

Abortion, Habitual↗
PubMed2005

A quality of care issue: appropriate use and efficacy knowledge of five contraceptive methods: views of men and women living in low socioeconomic settlements of Karachi, Pakistan.

OBJECTIVE: To assess knowledge regarding availability, affordability, appropriate use and efficacy for five non-permanent contraceptive methods. METHODS: Married Muslim women and men (500 each) were randomly selected from two low socioeconomic settlements in Karachi, Pakistan. Interviews to assess their knowledge on a range of contraceptive and abortion themes were conducted. Four hundred men and 357 women were selected from this larger sample based on their knowledge of condoms, withdrawal, oral pills, injectables and IUDs. RESULTS: Nearly half of the sampled men (56%) and women (48%) were contraceptive users. Knowledge regarding contraception, a specific method, its availability and affordability was high. Appropriate use knowledge for condoms was 73% among men (users 78%, non-users 60%; p-value < or = 0.001 ) and 5% among women. Efficacy knowledge was generally poor. CONCLUSIONS: Low knowledge levels regarding appropriate use and efficacy even among contraceptive users suggests, that quality of family planning services should not be limited to service delivery issues but extend to appropriate use and efficacy knowledge levels among clients.

Adult↗
PubMed1994

Immortalization of BALB/c mouse embryo fibroblasts alters SV40 large T-antigen interactions with the tumor suppressor p53 and results in a reduced SV40 transformation-efficiency.

In order to analyse the immortalizing and transforming potential of simian virus 40 (SV40), we compared the transformation efficiencies of SV40 in primary and in established BALB/c mouse fibroblasts. Five independently isolated clones of freshly immortalized normal fibroblasts (FTE cells) were established from precrisis BALB/c mouse embryo fibroblasts (pMEF cells) according to the protocol for establishing 3T3 cells (Todaro & Green, 1963). These cells expressed a wild-type p53 and were indistinguishable in all parameters analysed from original 3T3 cells kept in our laboratory. Using abortive infection to control gene dosage, followed by selection of transformed cells by cloning in soft agar, SV40 was able to transform primary cells with a much higher efficiency than 3T3 or FTE cells. Analysis of this unexpected result revealed that the different transformation efficiencies of SV40 in primary and established cells correlated with an altered cellular response to SV40 infection regarding metabolic stabilization of p53 complexed to large T during abortive infection. Whereas p53 in pMEF cells became stabilized upon abortive infection with SV40, p53 in 3T3 and FTE cells remained unstable. Our results strongly favour the hypothesis that metabolic stabilization and the ensuing higher levels of p53 in abortively infected cells enhance the transforming competence of large T.

Animals↗
PubMed1985

Prenatal selection and fetal development disturbances occurring in carriers of G6PD deficiency.

The incidence of spontaneous abortions in women with glucose-6-phosphate dehydrogenase (G6PD) deficiency was studied. In 78 families where the wife was a heterozygous carrier of G6PD deficiency the percentage of unsuccessful pregnancies with spontaneous abortions occurring in the first trimester was higher (21.7%, calculated from 258 pregnancies) than in the control group (9.3%, calculated from 678 pregnancies.

Abortion, Spontaneous↗
PubMed1989

Will Webster redefine Roe v. Wade? The Supreme Court could use a Missouri case to begin limiting abortion rights.

The U.S. Supreme Court's decision to review Webster v. Reproductive Health Services, a Missouri case that challenges the validity of legislative direction of public policy as outlined in Roe v. Wade, has fueled speculation that the Court will use the case to reconsider, and perhaps reverse, Roe. When the Supreme Court in Roe v. Wade opened the door to legalized abortion, it guaranteed only a woman's right to choose to terminate or continue a pregnancy without undue interference by the state--citing legitimate grounds for "due" interference by the state. In 1986 the Missouri legislature passed a statute that regulated medical practices related to abortion, including broad restrictions on the expenditure of state funds. Further, the state attempted to protect viable fetuses and directed physicians to perform certain tests to ascertain the baby's gestational age. It also contained a legislative finding that "life begins at conception." A challenge was filed almost immediately. In its application for Supreme Court review, Missouri questioned whether the Roe "trimester approach for selecting the test for which state regulation of abortion services is reviewed should be reconsidered and discarded in favor of a rational basis test." It further argued that if Missouri's statutory provisions are unconstitutional under Roe, then "Roe v. Wade should itself be reconsidered." Under current jurisprudence, it is debatable whether this formulation of the case will invite direct review of Roe. For the foreseeable future, the law will likely protect the notion that an abortion decision implicates a fundamental liberty interest.(ABSTRACT TRUNCATED AT 250 WORDS)

Abortion, Legal↗
PubMed1985

Safety of abortion and tubal sterilization performed separately versus concurrently.

Concurrent abortion and sterilization are preferred by many women to avoid a second hospitalization, operation, and, in some instances, general anesthesia. Several authors have shown concern, however, that the two procedures carry a higher risk of morbidity when performed concurrently versus separately. To determine whether the concurrent performance of sterilization and induced abortion is as safe as the two procedures performed separately, we selected women undergoing these procedures from two separate multicenter, prospective, national United States studies: the Joint Program for the Study of Abortion and the Collaborative Review of Sterilization. Using standard definitions of major morbidity, we calculated the crude rate of one or more major complications to be 0.9% for the abortion-only group, 1.7% for the group concurrent abortion and tubal sterilization. Thus our data suggest that performing concurrent abortion and sterilization is as safe as performing those procedures separately.

Abortion, Induced↗
PubMedDate not supplied

Investigating induced abortion in developing countries: methods and problems.

Interest in abortion research is reemerging, partly as a result of political changes and partly due to evidence of the contribution of induced abortion to maternal mortality in developing countries. Information is lacking on all aspects of induced abortion, particularly methodological issues. This article reviews the methodological dilemmas encountered in previous studies, which provide useful lessons for future research on induced abortion and its complications, including related deaths. Adverse health outcomes of induced abortion are emphasized, because these are largely avoidable with access to safe abortion services. The main sources of information are examined, and their relevance for assessing rates of induced abortion, complications, and mortality is addressed. Two of the major topics are the problems of identifying cases of induced abortion, abortion complications, and related deaths, and the difficulties of selecting a valid and representative sample of women having the outcome of interest, with an appropriate comparison group. The article concludes with a discussion of approaches for improving the accuracy, completeness, and representativeness of information on induced abortion. Although the prospects for high-quality information seem daunting, it is essential that methodological advances accompany program efforts to alleviate this important public health problem.

Abortion, Induced↗
PubMed1989

A farming systems study of abortion in dairy cattle on the Atherton Tableland. 3. Metabolic factors.

An association with a rank correlation of 0.55 (p = 0.06) was obtained between monthly rainfall and monthly abortions for a group of 24 farms in tropical Australia where cows grazed predominantly summer rain-dependent pasture. A similar association was found among cows grazing nitrogen-fertilised, irrigated pasture in winter in the same area. On farms with irrigated pasture the first service conception and abortion rates in herds which grazed intensively during the night (abortion 8.9%; first service conception 42.9%) differed significantly from those which grazed during the day (abortion 6.4%; first service conception 52.9%), and this suggested that increased abortion rates and decreased first conception rates may be part of the one syndrome. An hypothesis was developed that the feeding of immature nitrogen-fertilised pasture, rich in protein and stimulated by rain or irrigation, is associated with an increased abortion rate and a depressed conception rate. Other evidence included an increased susceptibility of first lactation cows to abortion, a lower abortion rate in late pregnant dry cows fed more mature pasture, a 20% repeat abortion rate in the population sampled and the lack of conclusive evidence for infectious and selected non-infectious agents. There were no other observed clinical signs in most aborting cows.

Abortion, Veterinary↗
PubMed2000

Teenage pregnancy.

OBJECTIVES: This article examines trends in teenage pregnancy in Canada, focussing on induced abortions, live births and fetal loss among women aged 15 to 19 in 1997. DATA SOURCES: The data come from the Hospital Morbidity Data Base and the Canadian Vital Statistics Data Base at Statistics Canada, and the annual Therapeutic Abortion Survey, conducted by the Canadian Institute for Health Information. Data on abortions performed on Canadian residents in the United States are from an annual survey of selected states. International data are from the Alan Guttmacher Institute. ANALYTICAL TECHNIQUES: Pregnancy rates, abortion rates, live birth rates and fetal loss rates are calculated using population counts of women in the age groups 15 to 17, 18 to 19, and 15 to 19. The percentages of pregnancies that ended in the three outcomes are also calculated for these years. MAIN RESULTS: The teenage pregnancy rate declined from 1994 to 1997, reflecting lower teenage birth and fetal loss rates. Through this period the abortion rate remained stable, with the result that slightly more than half of all teenage pregnancies ended in abortion by 1997. Younger teens are more likely to have an abortion than to give birth. The majority of pregnancies among older teens end in a live birth, although the number of live births is decreasing.

Abortion, Legal↗
PubMed1979

Abortion in early America.

This piece describes abortion practices in use from the 1600s to the 19th century among the inhabitants of North America. The abortive techniques of women from different ethnic and racial groups as found in historical literature are revealed. Thus, the point is made that abortion is not simply a "now issue" that effects select women. Instead, it is demonstrated that it is a widespread practice as solidly rooted in our past as it is in the present.

Abortion, Induced↗
PubMedDate not supplied

Comparison of contraceptive implant adopters and pill users in a family planning clinic in Baltimore.

All 133 women who began using the Norplant contraceptive implant between August and December of 1991 at a Planned Parenthood clinic in Baltimore were compared with a sample of 112 women who obtained prescriptions for the pill at the same clinic during the same time period. A multivariate analysis found that women of Medicaid are significantly more likely than those who are self-paying to select the implant rather than the pill. Similarly, compared with women who have had no children, those who have had two or more are also significantly more likely to choose the implant. However, adolescents and women who have had an abortion are no more likely than other women to select the implant.

Adolescent↗