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Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

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At least 577 records · Page 32Linked to original sources
PubMed2000

Summarizing the goodness of fit of generalized linear models for longitudinal data.

This paper extends four goodness-of-fit measures of a generalized linear model (GLM) to random effects and marginal models for longitudinal data. The four measures are the proportional reduction in entropy measure, the proportional reduction in deviance measure, the concordance correlation coefficient and the concordance index. The extended measures satisfy the basic requirements for measures of association. Two examples illustrate their use in model selection.

Adolescent↗
PubMed2005

Methods for assessing noninferiority with censored data.

In this paper we present the existing approaches to the problem of showing noninferiority with randomly right censored data. The main focus is on the choice of the discrepancy measure which is used to define the deviation from the classical null hypothesis, i.e. the noninferiority margin. Most methods are based on certain parametric or semiparametric assumptions. In contrast, a new, completely nonparametric approach is suggested and discussed.

Bias↗
PubMed2006

Application of adaptive designs--a review.

A literature search has been performed to review applications of the adaptive design methodology based on the combination test or conditional error function approach. Some features of the 60 papers identified are summarized, e.g., the specific methodology used, calendar year, country, impact factor of the journal, number of planned and performed stages respectively, stopping for futility boundaries, type of adaptations and others. A selection of the ten recent publications in journals with the highest impact factors is discussed in more detail. Most applications up to now aim at sample size reassessment, the majority of papers is coming from Germany. Although we found that renowned journals allow for sufficient space to present the new statistical methodology in all its necessary details, the general impression is that the presentation of the adaptive designs methodology in applied papers has to be improved. Education and development of standards could help to achieve this.

Data Interpretation, Statistical↗
PubMed2006

Dietary fibre.

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Colorectal Neoplasms↗