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At least 577 records · Page 32Linked to original sources
PubMed1984

[Neurochemical mechanisms of the involvement of sensorimotor cortex neurons in food and orienting-exploratory behavior].

Reactions of individual neurons to electrical stimulation of motivational areas of the lateral hypothalamus were studied in the somatosensory cortex of alert rabbits during micro. iontophoretic application of acetylcholine, norepinephrine or cycloheximide. The former two drugs altered equally the neuron reactions both on weak (inducing an orienting response) and strong stimulation (causing feeding behaviour). The latter drug also affected the neuron reactions. The feeding and orienting responses seem to be actualized through a specific peptide synthesis in the somatosensory cortex's neurons altering their sensitivity to neurotransmitters.

Acetylcholine↗
PubMedDate not supplied

[Effect of analgestics and narcotics on the potentials of the posterior roots evoked by stimulation of the sensorimotor cortex].

Experiments set up on unanesthetized, curarized cats demonstrated that sodium oxybutyrate in doses of 75--200 mg/kg and nembutal in doses of 5--20 mg/kg prolong the duration of corticospinal posterior roots potentials (PRP). The initial effect of morphine and promedol in doses of 1--3 and 0.5--1 mg/kg, respectively was not only a longer duration (by 30--40 msec), but also a higher amplitude of the PRP, evoked by the stimulation of the sensomotor cortex. Phentanyl used in a dose range of 0.01 to 0.06 mg/kg did not produce any changes in the descending PRP. Anesthetics (sodium oxybutyrate, nembutal, ether) and analgesics (morphine, phenadon) inhibited the corticospinal PRP, when used in large doses.

Analgesics, Opioid↗
PubMed1984

Interneurons of the cat sensorimotor cortex.

In this paper a review is given on the interneurons of the cerebral cortex, their subdivisions and neurophysiology. Special concern is given to short axon (local) interneurons and long-axon (association and callosal) stellate cells. Data obtained from simultaneous recordings of more than one neuron are also presented. However, further research is needed to demonstrate the essential role of the interneurons in information processing.

Animals↗
PubMed1983

[Ultrastructural changes in the neuropile of the sensorimotor cortex during long-term protein-calorie deficiency].

The effect of alimentary (protein-caloric) deficiency on the brain sensomotor cortex of mice was studied during their postnatal development. It was found that malnutrition of mice from day 10 to day 40 of postnatal period brought about the most remarkable changes in synaptic junctions located on the dendritic spines. They manifested destruction of the spine apparatus, reduction of the width of synaptic slits and of postsynaptic membranes. Dystrophic and destructive alterations are frequently encountered in dendrites, axon terminals, and myelinized axons, indicating the reduced compensatory functions of the CNS.

Animals↗
PubMed1984

[Influence of the sensorimotor cortex on single neurons of the nucleus gracilis in the cat].

The aim of this study was to investigate the functional role of the cortical projections to gracile nucleus. In unanesthetized cats single nuclear units projecting to the thalamus were tested for microstimulation of cortical foci (area 4) able to evoke single joint movements in contralateral hindlimb. A very significant percentage of gracile cells was influenced, very often in excitatory manner, if their receptive field was overlaying or very close to the joint controlled by a given cortical focus. Conversely, when the location of the receptive field was more distant, the percentage of responses and the incidence of excitatory effects decreased, inhibitions occurring more frequently. From a functional point of view, such an organization of the cortico-gracile control could be effective in modulating transmission of exteroceptive information from the region of the motor target (facilitation) as well as from adjacent ones (suppression). This arrangement could provide an higher resolution of afferent messages, in relation with the cortically induced movements.

Animals↗