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PubMed1984

[Classification of laryngotracheal stenoses in the adult].

A new classification for laryngotracheal stenoses in adults is proposed, based on 145 cases treated between 1965 and 1980. Three factors were analyzed when establishing this classification: the extent of laryngeal and tracheal cartilage involvement, laryngeal mobility, and the complexity of the lesions as a function of whether they were systematized or not. This new approach enables a more functional therapy for these stenosis to be instituted.

Adult↗
PubMed1986

Androgen-induced myogenesis and chondrogenesis in the larynx of Xenopus laevis.

We investigated a possible role for testosterone-induced cell proliferation in the development of sexual dimorphism in the larynx of South African clawed frogs, Xenopus laevis. Androgen-induced cell proliferation was studied using [3H]thymidine autoradiography. Nuclei of cartilage, perichondrium, and muscle were labeled in the larynx of sexually immature frogs of both sexes but not in adults. Cell proliferation did not occur with estradiol treatment nor was it seen in nonlaryngeal muscle or cartilage. Electron microscopic/autoradiographic studies of laryngeal muscle indicate that testosterone stimulates satellite cell division which later results in formation of myonuclei. We conclude that testosterone induces both chondrogenesis and myogenesis in juvenile larynx and that this process may contribute to the pronounced sexual dimorphism of the adult vocal organ.

Animals↗
PubMedDate not supplied

Significance and means by which laryngeal cancer invades thyroid cartilage.

Involvement of the thyroid cartilage attracts a high T rating in all systems of classification for carcinoma of the larynx. Evaluation of 145 patients with laryngeal cancer treated by total laryngectomy emphasizes the difficulties of preoperatively determining cartilage invasion. The operative specimen was serially sectioned and studied to determine the means by which ossified and nonossified thyroid cartilage is invaded by carcinoma. A minimum 5-year follow-up of these cases indicates the prognostic significance of such invasion.

Humans↗
PubMed1990

The ceratocricoid muscle.

One hundred and thirty-four hemilarynges were examined for the presence of the ceratocricoid muscle. This muscle arises from the cricoid cartilage, below the posterior cricoarytenoid muscle, and inserts onto the posterior aspect of the inferior horn of the thyroid cartilage. A prevalence of 6.3% was found. The anatomy, relations and innervation of the muscle are discussed.

Adult↗