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At least 595 records · Page 33Linked to original sources

Haematological and pathomorphological studies on chickens inoculated with transformation-defective sarcoma virus.

A transformation-defective mutant of Rous sarcoma virus (td PR-RSV-C) inoculated into chicken embryos caused a number of pathological changes in chickens after hatching. Disturbances in haematopoiesis were manifested by anaemia of different degree and by the presence of immature blood elements in the peripheral blood. The haematological picture of erythroblastosis was confirmed histologically. In addition to erythroblastosis, lymphoid leukosis and a proliferative lymphosarcoma-like tumour were demonstrated histologically.

Animals↗

[Primary lymphosarcoma of the prostate gland].

Two large tumor nodes of a total weight of about 100 g were removed from the prostate gland of a patient of 28 with the duration of the disease symptoms of approximately 3 1/2 months. Histological diagnosis of polymorphocellular sarcoma was made. On the 19th day postoperation the patient died with phlegmon of the small pelvis tissues in the presence of cachexia. The autopsy revealed a tumor of the prostate gland outgrowing into the soft tissues of the small pelvis without metastases. Histologically it was a diffuse prolymphocytic lymphosarcoma of the prostate gland with small-loop argirophilic reticulum. This neoplasia was combined with multiple glandular gastric polyps.

Adult↗

Eleven sites of cancer in black gold miners from Southern Africa: a geographic enquiry.

The 5-year study of cancer in black gold miners, 1964-68, previously reported (Robertson et al., 1971) has now been extended for a separate 8-year period, 1972-79. This allows analyses of all cancers together and of 6 less common sites of cancer severally: lymphosarcomas, colon and rectum, leukaemia, stomach, pancreas and buccal cavity and also of those too rare to classify. The malignancies are considered by territory of origin of the gold miners. Lesotho miners have significantly fewer (P less than 0.05) tumours of the lymphatic and haemopoietic tissues and Natal miners have the highest incidence rates for 5 of the 6 sites (excluding leukaemia). A simple grouping method is applied to determine which of the 11 sites of cancer in the miners have similar distributions in their 10 territories of origin. The aetiological implications of clusters over space of certain sites of cancer are discussed. Finally, temporal change over the years 1964-79 shows a significant decrease overall (P less than 0.01) in cases of lymphosarcomas and colo-rectal cancers and an increase (P less than 0.05) in stomach cancer. The rare tumour, Kaposi's sarcoma, has also decreased significantly between the 2 periods studied.

Adolescent↗