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PubMed2006

Endocrinology of the aging male.

Despite enormous medical progress during the past few decades, the last years of life are still accompanied by increasing ill health and disability. The ability to maintain active and independent living for as long as possible is a crucial factor for ageing healthily and with dignity. The most important and drastic gender differences in aging are related to the reproductive organs. In distinction to the course of reproductive ageing in women, with the rapid decline in sex hormones expressed by the cessation of menses, men experience a slow and continuous decline. This decline in endocrine function involves: a decrease of testosterone, dehydro epiandrosterone (DHEA), oestrogens, thyroid stimulating hormone (TSH), growth hormone (GH), IGF1, and melatonin. The decrease of sex hormones is concomitant with a temporary increase of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In addition sex hormone binding globulins (SHBG) increase with age resulting in further lowering the concentrations of free biologically active androgens. These hormonal changes are directly or indirectly associated with changes in body constitution, fat distribution (visceral obesity), muscle weakness, osteopenia, osteoporosis, urinary incontinence, loss of cognitive functioning, reduction in well being, depression, as well as sexual dysfunction. The laboratory and clinical findings of partial endocrine deficiencies in the aging male will be described and discussed in detail. With the prolongation of life expectancy both women and men today live 1/3 of their life with endocrine deficiencies. Interventions such as hormone replacement therapy may alleviate the debilitating conditions of secondary partial endocrine deficiencies by preventing the preventable and delaying the inevitable.

Aging↗
PubMed2006

[Sleep and sexuality].

Our knowledge about the multiple aspects of sleep functions are still insufficient. Concerning the relationship between sleep and sexuality there are four points of view to take into account. Two observations: a spontaneous sexual excitement during REM sleep and that some anxious dreams can produce also sexual arousal. Two hypotheses: the erotic pleasure could be easier to perceive in a sleeping or dreaming state than in a waking state and some sleeping troubles could have an important influence on the sexual life of a couple.

Humans↗
PubMed2006

Sexual dysfunction in female hypertensives.

PURPOSE: Hypertension and its treatment are known to produce sexual dysfunction in males. In our culture, women are not free to discuss issues of sexuality with their doctors. Hence, this phenomenon has not been explored in them. Notwithstanding this, cases occur in practice where noncompliance with dire consequences result from sexual dysfunction. This study was done to determine if any dysfunction existed among women as is commonly reported in males. METHODOLOGY: As part of a larger study on serum uric acid and lipid profile of adult Nigerian hypertensives, we sought information on sexual function in females. One group was newly diagnosed and treatment naïve, while the other was made up of known hypertensives on thiazides. The third group consisted of normotensive age-matched controls. FINDINGS: Six out of 44 (13.6%) in the first group, five out of 29 (17.2%) in the second group and two out of 43 (4.7%) in the control group reported sexual dysfunction. The commonest aspect encountered was reduced desire for intercourse. CONCLUSION: There was a tendency for hypertensive women to have more sexual dysfunction even before treatment than did controls. Larger studies should be undertaken and clinicians should probe this subject if poor compliance is suspected.

Antihypertensive Agents↗
PubMed2006

[Xuanju compound capsule combined with erogenous focus exercise is effective for premature ejaculation].

OBJECTIVE: To investigate the effect of the Chinese medicine Xuanju compound capsule combined with erogenous focus exercise on premature ejaculation. METHODS: Fifty-two patients with premature ejaculation were divided into a treatment group (n = 28) and a control group ( n = 24) , both treated by erogenous focus exercise and the former given Xuanju compound capsule in addition. After four weeks of treatment, comparisons were made of the sexual satisfaction between the two groups. RESULTS: The cure rate and the rate of improvement of sexual satisfaction were 21.43% and 67. 86% respectively in the treatment group, significantly higher than in the control group. CONCLUSION: Xuanju compound capsule combined with erogenous focus exercise is highly effective in the treatment of premature ejaculation, with few adverse effects.

Adult↗
PubMed1989

[Sterility and sexuality].

In some couples, an absence of pregnancy may be related to sexual difficulties. They should always be considered if the couples do not mention this subject. It is also necessary to keep in mind that sterility may result in sexual problems. In all cases, it is the physician's responsibility to listen to, reassure and comfort the couples who look to him/her for the realisation of their dream: having a child.

Ejaculation↗
PubMed1986

[Sexual disorders among men with myotonic dystrophy].

Sexual function was studied in 15 males with myotonic dystrophy. For this purpose a structural analysis was employed and blood levels of gonadotrophins and testosterone were radioimmunoassayed. Peculiar endocrine disorders were found to be largely responsible for disruption of the neurohumoral component of the copulative cycle. The results of the study may be useful for the treatment of sexual disturbances in myotonic dystrophy and for the differential diagnosis.

Adult↗
PubMed1985

True precocious puberty: a long-term complication in children with shunted non-tumoral hydrocephalus.

In 4/37 (10.8%) children, adolescents and young adults with successfully shunted hydrocephalus, puberty occurred or was occurring precociously, at an age ranging from 7.5 to 8.6 years, with a consequent impairment of their effective or predicted adult height as compared to the familial target height. All four patients had undergone a surgical intervention for the insertion of a ventricular-atrial or a ventricular-peritoneal shunt during the first year of life; since the last surgical shunt revision (at the age of 5 years) no relapse of hydrocephalus had been recorded. The authors conclude that precocious puberty is to be regarded as a not infrequent long-term complication in patients with successfully shunted hydrocephalus.

Adolescent↗
PubMed1994

[Sex anamnesis, sex counseling, sex therapy].

About each forth patient consulting a general practitioner because of any health problem suffers from a sexual dysfunction since longer time. The criterion for the necessity of treatment of sexual dysfunctions are caused by psychosocial factors. A good and exact exploration of the sexual symptoms provides informations both for psychological and organic causes of the dysfunction. One part of sexual dysfunctions can be improved by sexual counselling, if possible including the spouse/partner of the patient. If there are more severe conflicts, the indication for sexual, couple or individual psychotherapy has to be clarified. In addition to the medical treatment, there exist several suitable books of sexual information which can be recommended to the patients.

Female↗
PubMed1994

[Contraception and sexuality].

Contraception implies the responsible confrontation with fertility and sexuality. Contraceptive counselling deals directly or indirectly with sexuality and comprises therefore frequently sexual counselling. 25% of women consulting our Family Planning Clinic complain spontaneously about sexual difficulties. Out of these women one fifth suffer from sexual dysfunction related to the contraceptive method used. Hormonal contraception seems to include most frequently sexual dysfunction. The symptom most frequently complained about is lack of libido. There are typical patterns of correlation between sexual dysfunction, contraceptive compliance and side-effects of contraception which are of great important for contraceptive counselling.

Adolescent↗
PubMed1993

Sexuality and the older woman.

Problems in defining, reporting, and sampling the sexual experience of older women have limited the available information. It should be remembered, however, that an aging population is a sign of societal success, not failure. To date, there has not been a better educated, healthier, wealthier, better-housed, or more self-sufficient generation of older women that at present. Working in the area of sexuality can help improve an important issue in the quality of life for the older woman.

Aging↗