PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Tooth Remineralization”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 595 records · Page 33Linked to original sources
PubMed1999

Dentin bond strength: influence of laser irradiation, acid etching, and hypermineralization.

OBJECTIVE: The purpose of the present study was to investigate the effects of ND:YLF laser irradiation (1.31 J/cm2; 250 mJ per pulse), acid etching, and hypermineralization on the shear bond strength (SBS) of the Scotchbond Multi-Purpose Plus (3M Dental Products) bonding system. SUMMARY BACKGROUND DATA: Previous studies had shown that the pretreatment of the dentin substrate with laser irradiation can influence the SBS. METHODS: Sixty bovine incisors were selected and stored at -18 degrees C. Dentinal buccal surface was exposed and radiographs were taken to control dentin thickness. The specimens were separated into 2 groups: (1) the control, which was kept in distilled water at 4 degrees C; (2) the hypermineralized, which was kept in hypermineralizing solution at 4 degrees C for 14 days. Each group was divided into 3 subgroups according to the type of dentin pretreatment used: M (acid etching + primer + bond); AL (acid etching + primer + bond + laser); and LA (laser + acid etching + primer + bond). A standard composite resin cylinder (Z100-3M) was bonded to the dentinal surface and the SBS performed on an Instron machine (500 Kg load cell at 0.5 mm/min), followed by scanning electron microscopy (SEM) and x-ray diffraction analysis. RESULTS: Analysis of variance (ANOVA) determined that the pretreatments influenced the SBS values (p < 0.05): AL (9.96 MPa), M (7.28 MPa), and LA (4.87 MPa). The interaction between the group and pretreatment factors also influenced the SBS (p < 0.05). The highest values were obtained for the interaction control/AL (11.64 MPa). CONCLUSION: The results suggested that dentin treatment with laser after the application of the adhesive system is efficient in achieving higher bond strength and is promising as a possible new adhesive substrate.

Acid Etching, Dental↗
PubMed2000

Minimal intervention: a new concept for operative dentistry.

The term minimal intervention is relatively new in dentistry and has been introduced to suggest to the profession that it is time for change in the principles of operative dentistry. The disease should be treated first; the surgical approach should be undertaken only as a last resort and then with the removal of as little natural tooth structure as possible. This article discusses the advances in techniques and materials that have led to change and attempts to put them into perspective. Treatment should begin with identification and elimination of the disease. There will then be a need for limited restoration of actual cavitation arising from demineralization of the tooth crown. Restorations, per se, will not prevent or eliminate disease. Caries is a bacterial infection and, until the microflora is controlled, all restorations are at risk of further demineralization in remaining tooth structure. This leads to the continuum of replacement dentistry that keeps the profession occupied for much of its productive time. If this cycle is to be broken, the profession must first acknowledge the primacy of prevention.

Bacterial Infections↗
PubMed2000

Bond strengths of self-etching primer adhesives to in vitro-demineralized dentin following mineralizing treatment.

PURPOSE: The purpose of this study was to determine if treatment of experimentally demineralized dentin with a calcium phosphate precipitating (CPP) solution could restore the bond strength of self-etching adhesives to that of normal mineralized control values. MATERIALS AND METHODS: The occlusal surfaces of human teeth were exposed for bonding. The teeth were assigned to a mineralized control group or one of three demineralized (40% phosphoric acid for 60 s) experimental groups. One of the experimental groups remained untreated, while the other two were treated with the CPP solutions for either 1 or 10 min. All experimental groups were then chemically dehydrated with ascending acetone concentrations to prevent shrinkage prior to bonding with Clearfil Liner Bond 2 (LB2) or MacBond II (MBII). Composite buildups were made and vertically, serially sectioned into multiple slabs about 0.7 mm thick. Each slab was then trimmed for microtensile bond testing and SEM examination. RESULTS: Both self-etching adhesives produced high bond strengths to control mineralized dentin (ca 42 and 37 MPa for LB2 and MBII, respectively). Acid etching with 40% phosphoric acid for 60 s followed by chemical dehydration significantly lowered (p < 0.05) bond strength to 26 and 27 MPa for LB2 and MBII, respectively, and created hybrid layers between 7 and 8 microns thick. When the demineralized dentin was treated with the CPP solution for 1 min, the bond strengths increased (p < 0.05) to 39 for LB2 and 42 MPa for MBII, and the hybrid layers were 11 microns thick. Increasing the CPP treatment time to 10 min lowered (p < 0.05) bond strengths but increased the hybrid layer thickness to 16 to 20 microns. CONCLUSION: The use of calcium phosphate precipitating solutions may permit higher bond strengths of self-etching primers to demineralized (e.g., caries-affected) dentin.

Acid Etching, Dental↗
PubMedDate not supplied

In vivo rehardening of enamel eroded by a cola drink.

There are many concerns about the erosive effects of acidic beverages. In this study, the effects of Pepsi-Cola (pH 2.41) on bovine enamel and the rehardening effect resulting from intraoral exposure of the teeth were determined by microhardness testing (Vicker's Hardness Number). Bovine enamel specimens (VHN 380.00 +/- 12.74) were immersed in 100 ml of Pepsi-Cola for five minutes and subsequently exposed to human intraoral environment through the use of a removable resin plate. Microhardness testing was performed on specimens after one hour, twenty-four hours and forty-eight hours of exposure to an intraoral environment. The microhardness value was significantly (p < 0.05) reduced by the cola beverage (VHN 262.13 +/- 20.34), and significantly (p < 0.05) increased after intraoral exposure for one hour (VHN 299.75 +/- 26.86) and twenty-four hours (VHN 328.00 +/- 18.70). The difference in the microhardness between the twenty-four-hour group and the forty-eight-hour group (VHN 333.50 +/- 15.13) was not significant (p > 0.05). The microhardness value of the forty-eight-hour group was significantly less than the values recorded during the initial pre-study measurements p < 0.05).

Acids↗
PubMed2001

Methods of stopping or reversing early carious lesions fluoride: a European perspective.

The purpose of this review was to discuss the findings of the systematic review of the management of the early carious lesion with fluoride from a European perspective. The review was checked, and the overall finding that the evidence was incomplete was confirmed. It was suggested that the reason that few data were available was that clinical trials had not been designed to answer this question and that the baseline of healthy teeth and surfaces with very early lesions were rarely quantified. The European perspective would want to identify a clinical method that could manage these lesions better than the home use of fluoride toothpaste. Future research was recommended in the form of several systematic reviews and re-analysis of existing data. Only then could further studies be recommended. In modern European dentistry, restoring these lesions is not an option.

Cariostatic Agents↗
PubMed2001

[Comparative study of expression of homeobox gene Msx-1, Msx-2 mRNA during the hard tissue formation of mouse tooth development].

OBJECTIVE: To observe and compare the expression pattern of Msx-1, Msx-2 mRNA during the different stages of hard tissue formation in the first mandibular molar of mouse and investigate the relationship between the two genes. METHODS: First mandibular molar germs from 1, 3, 7 and 14-days old mouse were separated and reverse transcription-polymerase chain reaction was performed on the total RNA of them using Msx-1, Msx-2 specific primers separately. RESULTS: Expression of both genes were detected during the different stages of hard tissue formation in the mouse first mandibular molars, but there was some interesting differences in the quantitiy between the two genes. Msx-1 transcripts appeared at the 1 day postnatally, and increase through 3 day, 7 day, then maximally expressed at 14 days postnatally; while Msx-2 mRNA was seen and expressed maximally at the 3 days postnatally, then there was a gradual reduction at 7 days, and 14 days postnatally. CONCLUSIONS: The homeobox gene Msx-1, Msx-2 may play a role in the events of the hard tissue formation. The complementary expression pattern of them during the specific stage of hard tissue formation indicates that there may be some functional redundancy between them during the biomineralization.

Animals↗
PubMed2000

Effectiveness of two fluoride dentifrices to arrest root carious lesions.

PURPOSE: To compare the effectiveness of Prevident 5000 Plus (5,000 ppm F) and Colgate Winterfresh Gel (1100 ppm F) to arrest root carious lesions. MATERIALS AND METHODS: 201 subjects with at least one root carious lesion were recruited from dental school patients. They were randomly assigned to use either Prevident 5000 Plus (5000 ppm F) or Colgate Winterfresh Gel (1100 ppm F) as sodium fluoride in the same silica base. Measurements of lesion hardness, area, distance from the gingival margin, cavitation and plaque were recorded at baseline and after 3 months by a single examiner. RESULTS: After 3 months 38% of subjects using Prevident 5000 Plus and 10% using Winterfresh Gel had one or more lesions that had become hard (P < 0.001). Non-cavitated lesions at baseline were more likely to become hard than cavitated lesions. Compared to the Winterfresh group there was significant increase in the distance from the base of the lesion to the gingival margin and plaque scores were reduced in those using Prevident 5000 Plus.

Adult↗
PubMed2002

Dental caries. Diagnosis and treatment.

The diagnosis of tooth decay must go beyond the clinical detection of a carious lesion. The practitioner should assess the individual's risk factors as well as the activity of the lesion. Our traditional instrumentation has limitations. Therefore, researchers are urged to find new diagnostic tools to allow earlier detection, to predict disease activity and, finally, to assess the susceptibility of an individual.

Dental Caries↗
PubMed1999

The cariostatic mechanism of fluoride.

The benefits of using fluoride to prevent caries have been known for many years, but a complete understanding of this mechanism is still being researched. The fluoride concentration in the apatitic structure of enamel does not have as significant an effect on reducing caries as a continuous presence of fluoride in the plaque liquid. Concentrated, topical fluoride agents (such as in toothpaste, fluoride mouth rinses, gels, or varnishes) have a different mechanism of fluoride protection than low-concentration applications (such as fluoridated water). In initial caries lesions and plaque, concentrated agents form globules of a calcium fluoride-like material on the enamel surface. This material is fairly insoluble, possibly because it is coated with phosphates or proteins. This mechanism explains how the topical application of a fluoride varnish, two or three times a year, can result in caries reduction.

Apatites↗
PubMed1999

Treating hypersensitivity with fluoride varnish.

Dentinal hypersensitivity results when stimulation causes the fluid in open dentinal tubules to undergo pressure changes, which activates mechanoreceptor nerves and results in pain. Treatment with fluoride varnish forms a protective layer of calcium fluoride that prevents this fluid flow, thereby reducing dentinal sensitivity.

Calcium Fluoride↗
PubMed2001

Understanding the applications of microdentistry.

Microdentistry is a science-based tool of operative dentistry, and is an alternative to traditional dentistry. The structures and substructures of teeth have been generally misunderstood. Once these structures are understood, the goal of the microdentist is to identify unsound tooth structure, which is a threat to the long-term stability of the tooth, and then neutralize or remove those structures with minimal disruption of the surrounding sound tooth structure. Minimal disruption of sound tooth structure provides the additional patient benefit of reducing or eliminating the pain associated with traditional dentistry. This article reviews some of the newly discovered structures in human teeth and discusses methods of microdentistry used to preserve these structures.

Air Abrasion, Dental↗
PubMed1997

The mechanism of fluoride protection.

Since the 1940s, researchers have understood the positive effect of fluoride on anticaries activity. Several studies, beginning with the Cheektowaga study, showed that an increased number of concentrated fluoride applications also have a beneficial effect on anticaries activity. In fact, the continuous presence of high-fluoride concentrations has a more significant protective effect than enamel fluoride. A high-potency dentifrice is the ideal form with which to produce protective effects. This article describes how high-fluoride concentrations affect dental caries.

Acidulated Phosphate Fluoride↗
PubMed2000

Overtreatment.

Explore the source record for details and available documents.

Dental Fissures↗