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Results for “Biological Science Disciplines”

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PubMed2006

Automated structure extraction and XML conversion of life science database flat files.

In the light of the increasing number of biological databases, their integration is a fundamental prerequisite for answering complex biological questions. Database integration, therefore, is an important area of research in bioinformatics. Since most of the publicly available life science databases are still exclusively exchanged by means of proprietary flat files, database integration requires parsers for very different flat file formats. Unfortunately, the development and maintenance of database specific flat file parsers is a nontrivial and time-consuming task, which takes considerable effort in large-scale integration scenarios. This paper introduces heuristically based concepts for automatic structure extraction from life science database flat files. On the basis of these concepts the FlatEx prototype is developed for the automatic conversion of flat files into XML representations.

Algorithms↗
PubMed2006

The state of the art of nanobioscience in Japan.

This paper reviews a part of the state of the art of nanobioscience in Japan. The importance of combination and integration of interdisciplinary principles is emphasized for the development of nanobioscience. Biomagnetics, biomechanics, nanomachining, self-replicating cell model, neuronal network, drug delivery system, and tissue engineering are discussed.

Biological Science Disciplines↗
PubMed1991

A study of the teaching and learning of the biological sciences in nurse education.

The study was designed to explore the teaching and learning of the biological sciences in nurse education in an attempt to identify why some students are failing to support their practice with theory. Questionnaires were sent to third-year nurse students (n = 140) and nurse teachers (n = 43) in three schools of nursing. Several findings emerged from the study: (a) the balance between the behavioural and biological sciences in nurse education was perceived by the students as being too much in favour of the behavioural sciences; (b) the level of knowledge from the biological science taught was perceived by the students as being inappropriate for RGN training; (c) teachers felt inadequately prepared to teach the biological sciences and, similarly, nurse students felt inadequately prepared in these sciences; and (d) self-directed methods of teaching and learning, although used most frequently, were perceived by the students as being the most ineffective.

Biological Science Disciplines↗
PubMed1996

Dental and life science students: a comparison of approaches to study and course perceptions.

Approaches to study and course perceptions were investigated and compared in both junior and senior students on a vocational course (dentistry) and on a non-vocational course (life sciences) using standard questionnaires. Junior dental students reported significantly greater tendencies towards both Deep and Surface Approaches than junior life science students. They also had significantly higher scores for Achieving Approach, but in senior students this trend was reversed. Final year dental students experienced greater workloads and less freedom in learning than life science students and they also reported less organized study methods. These course perceptions demonstrate similar trends to those reported by Ramsden (1991). The implications for the courses concerned and for curriculum development are considered.

Attitude↗
PubMed2006

Science in the undergraduate curriculum during the 20th century.

BACKGROUND: The conflict between the art and science of medical practice has always posed problems for the presentation of the scientific basis of medicine to medical students. This issue is examined by a brief description of the changing methods of medical education over the last century. OBSERVATIONS: The various approaches to attempting to teach the scientific basis of medical practice are discussed, together with the increasing complexities that followed the explosion of knowledge in the basic biological fields towards the end of the 20th century. Although progress was made by a more integrated approach to medical education, there are still considerable problems in presenting the basic sciences to students in a way that convinces them that such material is relevant to their future practice. CONCLUSIONS: A more broadly based background in modern biology, including evolutionary biology and biological complexity, would undoubtedly better prepare students for dealing with the infinite complexities they will encounter in sick people.

Biological Science Disciplines↗
PubMed2004

Analysis of New Zealand's research productivity in ophthalmology and vision science: 1993-2002.

AIM: To assess New Zealand's research productivity in the area of ophthalmology and vision science over the decade 1993-2002. METHODS: New Zealand-based researchers involved in ophthalmology or vision science research, including ophthalmologists, optometrists and vision scientists were identified via professional colleges, universities and electronic databases. Peer-reviewed publications by these authors were identified by both searching electronic databases (MEDLINE/Pubmed) and personal communication with individual researchers. RESULTS: Eighty-five New Zealand-based researchers involved in ophthalmology or vision science research published 446 articles in 84 scientific journals during the 10-year period. The cohort consisted of 59 ophthalmologists and 26 other researchers based in a diverse range of ophthalmology, optometry and university departments. Significant collaboration was observed between groups within New Zealand and with international institutions. Comparing ophthalmologists and 'other' researchers, ophthalmologists produced 69% of all ophthalmology and vision science research publications and those classified as 'active ophthalmologist researchers' published an average of 11 (range 5-55) papers each during this decade, compared to eight (range 5-25) for the group 'other active researchers'. This was also reflected in the high productivity rate by ophthalmologists of 277 publications per 1000. Publications were identified in a wide range of journals with the majority in top 20-ranked ophthalmology journals. The trend over the decade highlighted an increase in number of scientific publications, from 43 per annum in 1993, to 68 per annum in 2002. CONCLUSIONS: Despite a relatively small and geographically isolated population, New Zealand ophthalmology and vision science research is highly active and collaborative, with significantly increased research productivity during the period 1993-2002. The present study is the first to document these trends and provides strong evidence to justify continued support for ophthalmology and vision science research in New Zealand.

Bibliometrics↗
PubMed1997

The end of science?

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Biological Science Disciplines↗
PubMed2003

Chemical versus biological explanations: interdisciplinarity and reductionism in the 19th century life sciences.

This paper analyzes four controversies in the 19th century life sciences: the nature of fermentation, the nature of infectious diseases, the generation of life from inanimate matter, and vitalism. All these controversies appear to concern chemical versus biological explanations, suggesting that reduction of biology to chemistry was the common underlying issue. My analysis rejects such interpretations, including the labels for explanation, and instead points out sophisticated forms of interdisciplinarity between chemistry, medicine, and biology in the first three debates. I argue that the philosophically favored perspective on reductionism, historically induced by a few physicians in the fourth debate, leads us astray from understanding interdisciplinary research.

Biological Science Disciplines↗
PubMed1996

The dental curriculum: what should be new in the 21st century?

Dental education is at a critical juncture. The success of water fluoridation has reduced the caries burden of Americans and, consequently, has raised questions about the disproportionate technical emphasis on treating the sequelae of caries in US dental schools. Additionally, several powerful external factors-such as changing demographics, advances in biological science, fundamental changes in our health care delivery system, and a modest US economy-are forcing dental educators to question the appropriateness of retaining the current dental curriculum into the 21st century. The author considers these factors, suggests what type of dentist will be needed by society in approximately 20 years, and concludes that today's dental educational system is inadequate to produce such a dentist. Several elements, in addition to technical excellence, are required for the dental curriculum, including major changes in pedagogy, relevant science training, practical fluency in medicine, an increased mix of stomatologic skills, and broader contact with other health care providers.

Biological Science Disciplines↗
PubMedDate not supplied

Innovating lifetime microscopy: a compact and simple tool for life sciences, screening, and diagnostics.

Fluorescence lifetime imaging microscopy (FLIM) allows the investigation of the physicochemical environment of fluorochromes and protein-protein interaction mapping by Forster resonance energy transfer (FRET) in living cells. However, simpler and cheaper solutions are required before this powerful analytical technique finds a broader application in the life sciences. Wide-field frequency-domain FLIM represents a solution whose application is currently limited by the need for multichannel-plate image intensifiers. We recently showed the feasibility of using a charge-coupled device/complementory metal-oxide semiconductor (CCD/CMOS) hybrid lock-in imager, originally developed for 3-D vision, as an add-on device for lifetime measurements on existing wide-field microscopes. In the present work, the performance of the setup is validated by comparison with well-established wide-field frequency-domain FLIM measurements. Furthermore, we combine the lock-in imager with solid-state light sources. This results in a simple, inexpensive, and compact FLIM system, operating at a video rate and capable of single-shot acquisition by virtue of the unique parallel retrieval of two phase-dependent images. This novel FLIM setup is used for cellular and FRET imaging, and for high-throughput and fast imaging applications. The all-solid-state design bridges the technological gap that limits the use of FLIM in areas such as drug discovery and medical diagnostics.

Biological Science Disciplines↗
PubMed2001

Free-electron lasers. Status and applications.

A free-electron laser consists of an electron beam propagating through a periodic magnetic field. Today such lasers are used for research in materials science, chemical technology, biophysical science, medical applications, surface studies, and solid-state physics. Free-electron lasers with higher average power and shorter wavelengths are under development. Future applications range from industrial processing of materials to light sources for soft and hard x-rays.

Biochemical Phenomena↗