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At least 613 records · Page 34Linked to original sources
PubMed1984

[So-called carcinosarcoma of the breast--report of 4 cases].

Four cases of so-called carcinosarcoma of the breast were studied histopathologically. The patients were females aged 44, 37, 44 and 77 who were admitted to the Cancer Institute Hospital for breast tumors. Histologically, the tumors showed proliferation of sarcomatous cells with relatively small amounts of papillotubular carcinoma or scirrhous carcinoma. There were transitions between the sarcomatous portion and carcinoma. Two cases showed squamous metaplasia merging into the sarcomatous component, whereas the other 2 showed transition from adenocarcinoma to sarcomatous element. Lymph nodal metastases in 2 cases were papillotubular carcinoma. One patient died of lung and brain metastases, and autopsy revealed only sarcomatous element.

Adult↗
PubMed1984

[So-called gastric carcinosarcoma--a case of chondrosarcomatous undifferentiated in the metastatic foci].

A case of so-called gastric carcinosaroma in a 70-year-old man was presented. The primary tumor measuring 5.6 X 5.4 cm was located in the gastric antrum and had the appearance of Borrmann 2 type. A massive metastatic tumor was found in the pyloric lymph nodes. Histologically, the primary tumor was predominantly composed of papillary adenocarcinoma invading to the muscle layer with lymphatic and vascular involvements. Atypical spindle cells occasionally intervened between carcinoma nests. The metastatic tumor consisted of mixed papillary adenocarcinoma and well differentiated chondrosarcoma with transitional areas by atypical spindle cells. Therefore, it was suggested that sarcomatous components in the present case were derived from carcinoma cells by undifferentiated. Three cases of gastric carcinosarcoma reported in Japan were reviewed, and their histogenesis was discussed as compared with the present case.

Adenocarcinoma, Papillary↗
PubMed1980

Renal carcinosarcoma. Ultrastructure and transplantation into athymic mice.

An adult renal carcinosarcoma was studied by light and transmission electron microscopy. A portion of the tumor was transplanted and serially passed in athymic mice. The neoplasm consisted in part of typical renal cell carcinoma. The sarcomatous portion showed definite differentiation into bone, cartilage, and skeletal and smooth muscle. Hilar lymph nodes were involved by carcinoma, whereas the renal vein and recurrent tumor in the flank incision consisted of sarcoma. Only the sarcomatous tissue was transplanted into mice, and no carcinoma appeared during serial passages.

Adenocarcinoma↗
PubMed1982

Syndrome of inappropriate secretion of antidiuretic hormone in association with pulmonary carcinosarcoma.

A smoking patient presented with altered mental status, left sided weakness, and an opacity on the chest roentgenogram. During hospitalization he developed hyponatremia, which was corrected with hypertonic saline solution, fluid restriction, and demethylchlortetracycline. The clinical presentation and the laboratory findings supported the diagnosis of the syndrome of inappropriate secretion of antidiuretic hormone. This was believed to be associated with the pulmonary carcinosarcoma documented at necropsy.

Aged↗
PubMed1981

Polypoid carcinoma of the uterine cervix simulating "pseudosarcoma" and "carcinosarcoma" of esophagus and upper respiratory tract.

The patient presented with a polypoid mass, arising from the uterine cervix. Histologically the mass appeared to have two components, both of which were malignant. The first component was a surface squamous cell carcinoma, while the second was an infiltrating pseudosarcomatous lesion. The polypoid tumor mimics lesions which arise in the esophagus, pharynx, larynx, and mouth, and which have been variously classified as pseudosarcoma or carcinosarcoma. Treatment consisted of applications of radium followed, in 5 months, by radical abdominal hysterectomy and pelvic lymphadenectomy. The patient remains free of any clinical recurrence of the tumor after more than 2 years, suggesting a favorable prognosis. Similar lesions occurring elsewhere in the body also have a low propensity for metastases.

Carcinosarcoma↗
PubMed1995

Carcinosarcoma of the salivary gland on CT.

Three cases of carcinosarcoma of the salivary gland, two in the submandibular gland, and one in the parotid, were investigated with CT and exhibited a variety of findings. The density of the tumors was lower than that of normal submandibular tissue. A calcification was found in one case. One case showed extensive lymphadenopathy. The parotid lesion had low central density with an enhancing margin.

Aged↗
PubMedDate not supplied

Quantitative investigation of the changes in the cell composition of the spleen during the growth of Worker's carcinosarcoma.

The weight of the spleen and its cell composition as a function of the weight of the tumor was studied during the development of Worker's carcinosarcoma. The progression of the dependence is presented in the appropriate mathematical form. It is shown that with development of the process of tumor enlargement, erythro- and myelopoiesis are intensified in the spleen. The overall quantity of erythroblastic elements reaches a maximum value when the weight of the tumor reaches 30 g and subsequently remains at the same level. The kinetic curves of the changes in the number of lymphocytes in the spleen and also their graphical dependence on the weight of the tumor are of an extreme character. At late stages in the development of the tumor, the number of cells of the granulocyte type begins to increase.

Animals↗
PubMed1995

[Pedicled polypoid carcinosarcoma: a very rare esophageal tumor].

Neoplasms of the esophagus normally appear either as a exophytic-polypoid form, or as an infiltrating carcinoma or as an ulcerating tumor. We report on a 86 year old man suffering from the rare case of a pedicle polypoid tumor of the esophagus histologically diagnosed as a carcinosarcoma. We discuss the histological problems and our diagnostic and therapeutic proceeding.

Aged↗
PubMed1979

[Follicular carcinoma with sarcomatoid dedifferentiation or thyroid gland carcinosarcoma?].

Thyroid carcinoma may at times display unusual clinical and anatomo-pathologic behaviour. The case of a female patient associating goiter of long standing with a fulminating terminal course is presented. Since the patient was never treated, the evolution of her condition is thought to reflect the natural biologic behaviour of the disease process. Pathologic examination revealed the co-existence of both follicular and anaplastic carcinoma within the primary lesion. Moreover, metastases were either entirely follicular or poorly differentiated in structure, and occasionally even of striking sarcomatoid appearance. The possibility of carcinosarcoma was entertained but dismissed in view of the recent literature. Rather, the hypothesis of tumour dedifferentiation offers a more satisfactory explanation for the clinical course and pathologic findings.

Aged↗
PubMed1995

[Carcinosarcoma of the gallbladder].

The authors present a case of carcinosarcoma of the gallbladder, discussing its possible histological origin, clinical picture, and recommended therapeutic approaches. Only 30 cases have so far been reported. The case described was seen because of a painless large volume mass in the right hypochondrium. She was surgically treated with a complete resection of the gross tumor including a portion of choledochus, followed by chemotherapy. The survival was of 20 months.

Carcinosarcoma↗
PubMed1994

[Cause of rare pulmonary tumors. Two cases of pulmonary carcinosarcoma].

Two cases of primary pulmonary carcinosarcoma in men, aged 59 and 57 years, have been described. These are 100-th and 101-st descriptions in the world literature, being the second and third in Poland. The preoperative diagnosis of malignant neoplasm of endobronchial tumour was established on the basis of cytologic examination of sputum and specimen from bronchus. While the peripheral tumour was diagnose on the basis of fine needle transthoracic biopsy. The ultimate diagnosis was made by relying on histological examination, as well as after application of monoclonal antibodies. Cytokeratin and vimentin expression were detected in endobronchial neoplasm, but only cytokeratin expression was disclosed in the neoplasm peripherally in the lung parenchyma. The authors focus the attention on the increase, evidenced in the last ten years, of primary malignant and non-malignant, uniform and mixed mesenchymal tumours of the lungs, as well as on the relevant new problems and difficulties in microscopic preoperative diagnosis.

Carcinosarcoma↗
PubMed1994

[Carcinosarcoma of the bladder. Apropos of two cases].

The authors report two cases of carcinosarcoma of the bladder, review the literature, and study the clinical, histological, therapeutic and evolutive aspects of this unusual tumor. It is a rare tumor which represent less than 0.5 per cent of all cancers of the bladder. It is three times more frequent in men than in women. Hematuria is the most frequent alarming symptom and pathogenesis is still a matter of debate. Diagnosis is based on the pathological examination including immunohistochemical study and, if necessary, with electron microscopy examination. The tumor contains two highly malignant cellular components: one is epithelial and the other is mesenchymal. Treatment is not well codified. Early diagnosis and radical cystectomy seem to improve the prognosis, which is usually poor. 5 year survival rate is about 20 per cent.

Carcinosarcoma↗
PubMed1994

[Esophageal carcinosarcoma: morphologic and cytometric study].

Carcinosarcoma of the esophagus is a rare malignant neoplasm composed by both carcinomatous (epithelial) and sarcomatous (mesodermal) elements. We report a case, diagnosed by biopsy an endoscopic brushing. Cytometric analysis was also performed.

Carcinosarcoma↗
PubMed1994

[Pulmonary carcinosarcoma].

Sarcomatoid carcinomas of the lung are uncommon neoplasms; the concurrent presence of malignant epithelial and sarcomatoid spindle cell components show a high malignancy. Lymph node metastases at presentation is an important prognostic factor, on the other way the most patients with sarcomatoid carcinoma of the lung usually presented at an advanced stage that needed a complementary therapy. The Authors report about one surgical case of pulmonary carcinosarcoma recently observed without lymph node metastases; the literature is reviewed and the histogenesis is discussed.

Carcinosarcoma↗
PubMedDate not supplied

Carcinosarcoma of the kidney (nephroblastoma in an adult). Case report.

There was reported a case of a 57-year-old man with right renal colics and haematuria for the past 12 years, supposed to be caused by renal cysts and pyelonephritis. The latest echographs and functional explorations show an expanded right kidney with frequent cysts. The extirpated kidney is about 12/15 cm in size and has an encephaloid tumour in the pyelocalycial areas penetrating in the surrounding parenchyma. The histological picture is that of a carcinosarcoma, showing a possible origin in the restant multipotent cells of the nephrogenic blastoma.

Carcinosarcoma↗
PubMed1993

[Cytomorphologic characteristics of esophageal carcinosarcoma (pseudosarcoma)].

We report a case of carcinosarcoma or pseudosarcoma of the esophagus, diagnosed through biopsy and endoscopic brush. We also describe several histogenetics hypothesis about this infrequent neoplasm and the difficulty of its diagnosis by means of endoscopy. We emphasize the endoscopic brush positivity and the description of its cytologic characteristics.

Carcinosarcoma↗