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At least 613 records · Page 34Linked to original sources
PubMed2002

[Sciatica secondary to a presacral abscess as the first manifestation of Crohn's disease].

Presacral abscess is a rare musculoskeletal complication of Crohn's disease. The clinical picture is sometimes insidious and a delay in diagnosis may increase morbidity. Abdominal-pelvic computerized axial tomography (CAT) has proven to be very useful in the diagnosis of this entity, which usually requires surgical treatment. We present the case of a 22-year-old man who presented to hospital for colic-type abdominal pain of 6 months' evolution and intermittent episodes of joint pain. The patient also presented mechanical pain in the right gluteus muscle of two weeks' evolution irradiating to the posterior side of the muscle. Complementary investigations confirmed the suspected diagnosis of Crohn's disease and showed presacral abscess. Treatment was surgical.

Abscess↗
PubMed2005

[Percutaneous treatment of a gas containing epidural pseudocyst: an uncommon cause of sciatica].

Gas containing epidural pseudocyst is a rare cause of lumbar radicular compression. We present the case of a 42 year old woman presenting with right L5 radicular pain. CT showed vacuum phenomenon and a gas containing epidural pseudocyst compressing the right L5 root. Resolution of radicular pain occurred following CT guided aspiration and steroid injection. The patient remained asymptomatic at one year follow-up.

Cysts↗
PubMed2003

Lamotrigine for intractable sciatica: correlation between dose, plasma concentration and analgesia.

An open trial was conducted to study the potential efficacy of the antiepileptic agent lamotrigine in relieving the sciatic pain and the relationship between lamotrigine dosage, plasma concentration and the clinical response. Subsequent to a 1 week washout period from previous analgesics, lamotrigine dose was titrated on a weekly basis from 25 to 400mg/day and was maintained at that dose for additional 4 weeks. Spontaneous pain, the Short Form McGill Pain Questionnaire (SFMPQ), the Straight Leg Raise (SLR) test, and range of motion of the lumbar spine (leaning foreword, to the affected side) were used to assess lamotrigine efficacy. Lamotrigine plasma concentration was tested at the end of each week during the titration period and at the end of the study. Fourteen patients were enrolled in the study. All outcome measurers improved compared to baseline during the titration period, but reached a statistically significant level of improvement only at the 400mg dose. A linear correlation was found between mean lamotrigine dose, mean plasma concentration and mean weekly spontaneous pain, mean SLR and mean bending the affected side, but not with the SFMPQ score. Study results suggest lamotrigine is a potentially effective and safe compound for the treatment of painful lumbar radiculopathy, and that it is likely to act in a dose- and plasma concentration-dependent fashion.

Adult↗
PubMed1982

[Diagnostic importance of CT examination of the lumbosacral region of patients with lumbo-sciatica (author's transl].

In 160 patients with lumbo-sciatic complaints, CT examinations of the lumbo-sacral region were carried out. In 106 of these cases, which were controlled by myelography and/or operation, the CT diagnosis was correct in 74%. In 19%, the CT findings were uncertain, and in 7% they were wrong. A reliable CT diagnosis could be made mainly in the case of a medial or medio-lateral disc herniation of a size above 0.5 cm in diameter if the patient was not operated previously, and in extremely lateral prolapses into the intervertebral foramen without myelographic changes. Small medial protrusions, specially within a narrow spinal canal, or postoperative controls often gave rise to uncertain findings. However, osseous changes as compressions of the lateral recess or the narrow spine syndrome were demonstrated usually better by CT than on routine radiograms. Nevertheless, the indication for the performance of a lumbo-sacral CT should be kept narrow and should be limited to cases with clear-cut radicular signs.

Adult↗