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Is fish consumption safe?

Louisiana's vital seafood industry provides nearly 40% of domestic seafood production. Unlike Louisianans, most Americans do not enjoy fresh seafood, yet manage to eat over 4 billion pounds of seafood annually, most of it foreign, frozen, and fried! America's commercial fisheries now face crippling economic and environmental pressures from seafood imports, over-fishing, urban and agricultural wastewater runoff, harmful algal blooms, and coastal wetlands loss. As a result of these ecosystem stresses, seafood-borne disease now causes 37% of all foodborne illness in the United States. Despite recent advisories on high mercury-containing finfish consumption, seafood provides more than a third of the world with essential dietary protein, rich in cardiovascular-protective omega-3 polyunsaturated fatty acids. Louisiana and other coastal-state physicians can effectively curtail the rising threat of local seafood-borne disease outbreaks by supporting responsible coastal restoration and regulation of commercial fishing, and by recommending careful inspection, selection, and preparation of seafood.

Botulism↗

Is shellfish consumption safe?

Louisiana provides nearly 40% of domestic seafood production. America's commercial fisheries, especially coastal shellfish fisheries, now face crippling economic and environmental pressures from seafood imports, over-fishing, urban and agricultural wastewater runoff, harmful algal blooms, and coastal wetlands loss. As a result of these ecosystem stresses, seafood-borne disease now causes 37% of all foodborne illness in the United States. Louisiana and other coastal-state physicians can effectively curtail the rising threat of local shellfish-borne disease outbreaks by supporting responsible coastal restoration and regulation of commercial shell-fishing, especially oyster fishing, and by recommending careful selection and preparation of all shellfish and crustaceans.

Arsenic Poisoning↗

[The survey of 21 cases of human rabies in Anlong county in Guizhou province].

OBJECTIVE: To analyze 21 cases of rabies from February 8 to May 1 in 2004 in Anlong county in Guizhou province, and to explore the possible factors causing the epidemics. METHODS: 21 cases of rabies were investigated. The canine brains were collected, and indirect immunofluorescence assay was used to detect rabies virus antigen in the brains. RESULTS: From February 8 to May 1st in this year, 21 cases of rabies were reported, with 5.12/100,000 of the prevalence rate. Dogs accounted for 20 cases, and cat for one case. Median incubation period was 36.52 days, but less than 15 days in 6 cases. Among 21 cases, 17 cases were not correctly treated, and 9 cases received vaccine, with 3 cases vaccinated in time. No cases received passive immunization of antirabies serum or human antirabies immune globulin. A total of 73 dogs' brains were examined for rabies viral antigen by IFA, and 9 (12.33%) were positive. CONCLUSION: The increasing number of dog, high rate of virus carrier in dogs, incorrect treatment of the wound, and as well as low inoculating rate of rabies vaccine might be responsible for the outbreak of rabies in Anlong county.

Adolescent↗

[Current knowledge on human trichinellosis].

Until the beginning of the nineties, the control of trichinellosis was thought to be a solved problem in Europe. However, as a consequence of social, economical and ecological changes in Central Eastern and Eastern Europe in the past decade, trichinellosis became a re-emerging infectious disease in the region. Molecular genetic studies demonstrated that at least two Trichinella species can be responsible for trichinellosis outbreaks in the region, and the epidemiology of trichinellosis is more complex than previously thought. Although Trichinella spiralis has been successfully eradicated in Hungary, it was recently demonstrated that Trichinella britovi persists in the sylvatic cycle. In view of the considerable epidemiological changes in the region, the aim of this review is to summarise the current knowledge on the clinical aspects of human trichinellosis.

Animals↗

Six areas lead national early immunization drive.

On June 13, 1991, President George Bush announced in a White House ceremony a local planning effort to break down barriers and provide better access to immunization in six representative localities "to solve the problem of late immunization." (children need to be immunized appropriately by their second birthday, not just in time for school.). The community "Immunization Action Plans" (IAP) are one of several Federal, State, and local responses to an outbreak of measles that produced 27,600 cases and 89 deaths in 1990. The community effort and subsequent early childhood immunization plans around the country are also part of a much broader effort initiated by Secretary Sullivan as a Healthy People Year 2000 goal to increase immunization levels to at least 90 percent for the nation's children by their second birthday. These efforts also respond to 13 recommendations for improving immunization availability made by the National Vaccine Advisory Committee in January 1991. The recommendations focused on improvements in the management of immunization delivery and in methods for measuring immunization status, increasing appropriate consumer demand, and other prevention needs. Although measles prompted the action, the immunization initiative is aimed also at eight other communicable childhood diseases--diphtheria, tetanus, pertussis or whooping cough, poliomyelitis, mumps, rubella, and Haemophilus influenza type b that causes bacterial meningitis, and hepatitis B. Details are described of the immunization action plans developed by Dallas, TX; Maricopa County (Phoenix), AZ; South Dakota; Detroit, MI; San Diego, CA; and Philadelphia, PA, to ensure that children are fully immunized not just by the time they enter school but by age 2 years. The six were chosen by the Centers for Disease Control as representative of many without adequate childhood immunization coverage.

Arizona↗

Surveillance of human listeriosis in France, 2001-2003.

Mandatory notification of listeriosis began in France in 1999. Enhanced public health surveillance, including routine molecular characterisation of Listeria monocytogenes strains, epidemiologic follow up of cases, and collection of food samples, has improved the sensitivity of outbreak detection and response. The incidence of listeriosis declined from 4.5 cases/million in 1999-2000 to approximately 3.5 cases/million during the period 2001-2003. Clinical, demographic and microbiological characteristics of listeriosis in France remained stable during this time period. Maternal-fetal infections accounted for 24% of all cases. Serovar 4b accounted for 49% of cases and 60% of case clusters. The incidence of listeriosis in France has declined and is now lower than in several other European countries.

Cluster Analysis↗

Polio eradication in India: current status.

India has reached the final stage of polio eradication. The polio partnership in India, under the leadership of the Government of India, mounted tremendous response to the outbreak. The progress since 2003 is the most significant in the history of polio eradication in India. Surveillance sensitivity was increased to reach the goal for polio eradication. Since nearly all polio cases now occurring in India are caused by type 1 poliovirus in children, monovalent oral polio vaccine type 1 (mOPV1) was introduced in select high-risk districts of UP, Bihar and Mumbai-Thane during the April and May 2005 National Immunisation Days and the June and August 2005 in 6 sub-national immunisation rounds. Strategies were also being implemented to improve the impact of supplementary immunisation activities in the high-risk areas. As a result of supplementary immunisation activities targeted using surveillance data, India has made striking progress towards polio eradication.

Child↗

Morbidity surveillance after Hurricane Katrina--Arkansas, Louisiana, Mississippi, and Texas, September 2005.

Hurricane Katrina made landfall on the U.S. Gulf Coast on August 29, 2005. Thousands of Gulf Coast residents evacuated and dispersed across the country, moving into hotels, private homes, and evacuation centers (ECs) in 30 states and the District of Columbia (DC). One goal of public health responders was to identify and prevent hurricane-related morbidity and mortality among affected populations, especially among those with limited access to health care and those who were living in crowded conditions. This report summarizes the challenges of conducting national surveillance after Hurricane Katrina, focusing on the role of CDC in coordinating surveillance and consolidating and interpreting morbidity data from jurisdictions that used diverse surveillance approaches. Aggregate morbidity data that were reported through Arkansas, Louisiana, Mississippi, and Texas to CDC during September 1-22, 2005 (before the Gulf Coast landfall of Hurricane Rita on September 24) are presented from ECs and health-care facilities (HCFs) that served affected populations in these states. Chronic diseases and injuries were the most common conditions reported by ECs and HCFs, respectively. To better prepare for future large-scale disasters with widespread impact, public health agencies and other partners are actively working to establish standardized guidelines and tools for morbidity surveillance. These guidelines will facilitate the interpretation and exchange of health information among multiple jurisdictions and public and private agencies during a disaster response to identify outbreaks and monitor health concerns.

Arkansas↗

Neonatal septicaemia--incidence, etiology and outcome. A 6-year analysis.

Between 1983 and 1988 we observed altogether 222 cases of neonatal septicemia and/or meningitis in our Department of Neonatology. The incidence was 8.46 per 1,000 liveborn infants. The case fatality rate amounted to 45.9%. The most frequently isolated causative agents were Escherichia coli (23.4%) followed by group B Streptococci (16.7%), Staphylococcus aureus (9.9%), Klebsiella pneumoniae species (8.8%), Serratia marcescens (7.9%), Pseudomonas aeruginosa and coagulase-negative Staphylococci each 5.9%. The report includes information about serotypes of Escherichia coli, group B Streptococci and plasmid patterns of Serratia marcescens. The latter was responsible for an outbreak of septicemia and meningitis with high mortality. The changing infection pattern reflects changes in the newborn population, especially in the patient structure of the neonatal intensive care unit, changes in the antibiotic policy and organizational problems.

Berlin↗

Occurrence of Cryptosporidium oocysts in sewage effluents and selected surface waters.

An existing method for the detection of Cryptosporidium oocysts in water was modified to investigate oocyst prevalence in large volumes of water. Surface waters and sewage effluents were filtered, eluted from the filter, and concentrated using centrifugation. The resultant pellet was then homogenized, sonicated, and placed on a sucrose gradient to separate oocysts from the sediment. The uppermost gradient layer was then examined by immunofluorescence using a labeled monoclonal antibody. Using this technique, average numbers of oocysts detected in raw and treated sewage were 5.18 X 10(3) and 1.30 X 10(3)/L, respectively. Filtered sewage effluents had significantly lower numbers of oocysts (10.0/L). These data show that sand filtration may reduce the concentrations of this parasite in waste waters. Highly variable oocyst numbers were encountered in surface waters. Since Cryptosporidium oocysts are frequently present in environmental waters, they could be responsible for waterborne outbreaks of disease.

Animals↗

Erythema infectiosum in a village primary school: clinical and virological studies.

In a questionnaire response to an outbreak of erythema infectiosum in a village primary school, 55 (46%) of the 121 pupils reported an illness with rash. Three of the 12 members of staff also developed a rash. Onset in most affected children was indicated by the classical ;slapped cheek' appearance of erythema infectiosum with subsequent spread of the rash to the extremities. However, in 17 (35%) of 49 children who provided additional clinical data, the rash spread either in the reverse direction or not at all. Nineteen children (39%) reported recurrence of the rash.Serological studies confirmed that human parvovirus was the cause of the outbreak. Forty-six (44%) of 104 children investigated had significant levels of virus-specific immunoglobulin (lg)M and/or lgG antibodies consistent with recent infection. Most infections occurred in older children. Human parvovirus infection was also confirmed in five of the 12 adults. These studies revealed a substantial number of subclinical episodes - 14 (22%) of 64 subjects who remained well had serological evidence of recent infection with human parovovirus. Significantly, 43 individuals (37% of those investigated) remained seronegative despite frequent exposure to infection within the school. This finding, together with the observed temporary interruption of the outbreak which coincided with school holidays substantiates the view that human parvovirus has a relatively low infectivity and requires close person-to-person contact for its transmission.

Adult↗

[Chronic urticaria. Etiologic and therapeutic evaluation of 150 cases. (author's transl)].

The study of one hundred and fifty cases of chronic urticaria observed, gave the following results: higher female frequency, usual beginning at adult age, relative absence of digestive problems. For the last of these results we nevertheless noted numerous insignificant functional features, a few examples of colitis, a number of cases of non-functioning gall-bladder. Frequency of sensitivity to foods, preservatives, colouring agents, medical substances, principally shown by provocation tests (the latter present a considerable interest, and merit frequent use); importance of bacterian, mycotic, parasitic origins; little importance of atopy; frequency of minor psychogenic disorders. A contributing role might be played by spasmophily. The therapy includes the following basic treatment; antihistaminic drugs (mainly hydroxyzine hydrochloride and cyproheptadine hydrochloride) and a diet which eliminates recognized urticaria causing foods. In addition, a supplementary treatment destined to eliminate the factors shown to be responsible for the outbreak, must be prescribed.

Adolescent↗

[Bouillaud's disease in Martinique. Epidemiological and nosological features].

From the epidemiological point of view there does not appear to be any particular geographical pattern of this disease. Indeed, it is poor living conditions, low family income, large family size and poor oro-dental hygiene which are responsable for the outbreak of small familial epidemics of acute rheumatic disease of the joints; from the clinical point of view, acute rheumatic joint disease presents no particular features in the Antilles. All the characteristics described in the classical works are found, including the malignant form, whose rarity is emphasised. A programme of prevention of rheumatic disease has yet to be started in the Antilles, and we feel that it should be a three-pronged attack: 1. More information to the general public on the necessity for rapid treatment of the symptoms; 2. Increased vigilance by the medical services in the fight against this disease of deprivation, and close collaboration with the social services; 3. Finally, the setting up of a specialised social cardiology service to supervise the young rheumatic patients, and to ensure that they are educated. Such arrangements would avoid the disorganisation sometimes experienced by the families and friends; it must be admitted that we sometimes have to prevail upon the family to allow the child to be transferred to a centre of social cardiology on the continent so that the young rheumatic patient may receive training for a career which is compatible with his or her handicap.

Adolescent↗

Arbovirus studies in Luanda, Angola. 1. Virological and serological studies during a yellow fever epidemic.

A yellow fever epidemic broke out in Luanda, Angola, in January 1971 and was halted in less than 3 months by prompt mass vaccination and intensive antimosquito measures. Nine strains of yellow fever virus were isolated from hospitalized cases, but attempts to isolate the virus from Aedes aegypti mosquitos failed. A serological survey for antibodies to arboviruses in 589 sera from unvaccinated persons showed that two arboviruses were circulating in the epidemic area: the yellow fever virus and the Chikungunya virus responsible for an outbreak of dengue-like disease that occurred shortly before the yellow fever epidemic.

Angola↗

[Incidence and significance of toxic and allergic contact dermatitis caused by machaerium scleroxylum Tul. (Pao ferro), a substitute wood for palisander (Dalbergia nigra All.)].

In recent years an increasing number of cases of primary irritant and allergic contact dermatitis has been observed after using the South-American timber Pao ferro (Machaerium scleroxylum). Since 1978 140 cases have come to our knowledge. The patients were mainly cabinet and furniture makers occupied in the sanding of veneer. Perioral dermatitis and cheilitis was also seen in persons playing the flute made of Pao ferro wood. Guinea pig sensitization experiments revealed a strong sensitizing capacity of the main wood constituent R-3,4-dimethoxydalbergione. Amounts of up to 2% were found in the heartwood. Mix-up of Brazilian rosewood (Dalbergia nigra) with its substitute (Machaerium scleroxylum) may occur accidently due to their similar appearance. However, a chemical differentiation is easily possible by determination of their constituents: while Pao ferro exclusively contains the strong sensitizer R-3,4-dimethoxydalbergione, the botanically related Brazilian rosewood (and also the East Indian rosewood--Dalbergia latifolia Roxb.) yields several other and weaker dalbergiones. In 41 of 55 patients tested epicutaneously with R-3,4-dimethoxydalbergione an acquired sensitivity could be demonstrated. The high amount of R-3,4-dimethoxydalbergione in Machaerium scleroxylum is primarily responsible for the outbreak of toxic dermatitis in veneer factories, half of which resulted in a sensitization. The risk of active sensitization is high if epicutaneous tests are carried out with the native wood dust. To avoid active sensitization it is better to test the pure constituent, if available, in a dilution of 0.1%.

Adolescent↗