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PubMed1975

The value of the fatty meal in oral cholecystography.

A fatty meal was given to 231 patients who had a well-visualized gallbladder with no stones. The radiological diagnoses on fluoroscopic spot films made before and after the fatty meal were compared. Only one case was diagnosed differently after the fatty meal. In 4 patients the post-fat film was useful in confirming a suspected diagnosis. Indications for administration of a fatty meal include (a) overlying gas shadows, (b) differentiation of a stone from a polyp, (c) adenomyomatosis, (d) a distended gallbladder, and (e) suspected common bile duct obstruction. In the absence of these indications, the time, effort, and cost involved in making the post-fat film are not justified by the additional diagnostic information obtained.

Cholecystography↗
PubMed1979

Ceruletide-assisted cholecystography: a clinical assessment.

The cholecystokinetic effect of ceruletide, a synthetic decapeptide similar in action to cholecystokinin, was examined in both a randomized and nonrandomized study in 81 patients scheduled for routine oral cholecystograms. Intramuscular injection of ceruletide in a dose of 0.3 microgram/kg resulted in a mean maximum contraction of the gallbladder of 68% and a mean time until maximum contraction of 28 minutes. Visualization of the cystic duct occurred in 57 patients (70%); the common duct was seen in 67 (83%). Ceruletide demonstrated superior gallbladder contraction when compared to fatty meals and demonstrated no interference with a subsequent upper gastrointestinal series.

Adult↗