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At least 631 records · Page 35Linked to original sources
PubMed1988

Effect of catheter ablation of the atrioventricular junction on quality of life and exercise tolerance in paroxysmal atrial fibrillation.

The effect of catheter ablation of the atrioventricular junction (AV) and implantation of a rate-adaptive pacemaker on quality of life and exercise capacity was evaluated prospectively in 12 consecutive patients with paroxysmal atrial fibrillation (AF). All patients had been demonstrated to have paroxysmal AF that was refractory to medical therapy over a long period of time (mean 9 +/- 7 years). Patients performed a symptom-limited treadmill exercise test on the day before catheter ablation and 6 weeks after hospital discharge. Quality of life was measured using the physical dimension of the McMaster Health Index Questionnaire and the Psychological General Well-Being Index before and 6 weeks after ablation. There were no serious complications related to catheter ablation or permanent pacemaker implantation. All patients remain in complete AV block with a completely paced rhythm at a mean follow-up of 8 +/- 2 months. The McMaster Health Index scores increased from a mean of 0.69 +/- 0.20 before to 0.92 +/- 0.14 after ablation (p = 0.002). The mean Psychological General Well-Being score improved from 59.8 +/- 14.8 at baseline to 84.9 +/- 13.6 6 weeks after discharge (p = 0.001). Treadmill exercise duration increased from 6.4 +/- 4.6 to 9.9 +/- 2.6 minutes (p = 0.03) and correlated strongly with changes in functional capacity measured with the McMaster Health Index (r = 0.70, p = 0.03). These results suggest that catheter ablation of the AV junction and implantation of a rate-adaptive pace-maker significantly improve the quality of life and exercise capacity of patients with paroxysmal AF refractory to medical therapy.

Aged↗
PubMed1991

Effect of yoga training on exercise tolerance in adolescents with childhood asthma.

Forty six young asthmatics with a history of childhood asthma were admitted for yoga training. Effects of training on resting pulmonary functions, exercise capacity, and exercise-induced bronchial lability index were measured. Yoga training resulted in a significant increase in pulmonary function and exercise capacity. A follow-up study spanning two years showed a good response with reduced symptom score and drug requirements in these subjects. It is concluded that yoga training is beneficial for young asthmatics.

Adolescent↗
PubMed1977

[Effectiveness of nifedipine on exercise tolerance in patients with angina pectoris. Comparison with a nitroderivative and a beta-blocking agent].

The effect of nifedipine on effort angina was investigated by means of exercise tests with bycicle ergometer and compared, in the same patients, with the effects of a nitroderivative and a betablocking agent. Five patients with stable effort angina entered the study, after an hemodynamic and contrasto-graphic control. According to the protocol of a latin square 5 X 5, all the patients received in a random sequence the following treatments: placebo, 1 c. orally; isosorbide dinitrate, 5 mg sublingually; propranolol, 40 mg orally; nifedipine, 10 mg sublingually; nifedipine, 10 mg orally. No significant change of any of the considered parameters was observed after the placebo. Isosorbide dinitrate and nifedipine produced significant increases of the duration of work before appearance of pain and EKG positivity, and of total work performed before anginal pain. Only the duration of work before EKG positivity was improved by propranolol. The comparisons between treatments showed no significant difference of the effects of the administered doses of isosorbide dinitrate and nifedipine. The improvements observed after propranolol were significantly lower than that observed after isosorbide dinitrate and oral nifedipine. On the basis of the observed changes of cardiac rate, maximal arterial pressure, ejection time index and triple product, the authors evaluate the possible mechanism of action of nifedipine.

Adolescent↗
PubMed1988

Impaired exercise tolerance after inferior vena caval interruption.

Four patients were evaluated for persistent dyspnea eight months to four years after inferior vena caval interruption for treatment of pulmonary emboli. Maximal exercise testing with gas-exchange analysis was performed. All patients attained less than 64 percent of predicted maximal oxygen uptake. Peak exercise heart rates were 85 percent or greater of predicted values. Arterial hypoxemia was not observed. The ratio of dead space to tidal volume (VD/VT) decreased with exercise, and the ratios of maximal exercise ventilation to maximal voluntary ventilation (VE/MVV) were less than 67 percent. These results suggest a cardiac rather than a ventilatory limitation to exercise. Inadequate venous blood return to the heart is the likely mechanism for the impaired exercise performances.

Adult↗
PubMed2006

The ventilatory anaerobic threshold is related to, but is lower than, the critical power, but does not explain exercise tolerance at this workrate.

AIM: The aim of the present study was to investigate the relationships between critical power (CP), maximal aerobic power and the anaerobic threshold and whether exercise time to exhaustion and work at the CP can be used as an index in the determination of endurance. METHODS: An incremental maximal cycle exercise test was performed on 30 untrained males aged 18-22 years. Lactate analysis was carried out on capillary blood samples at every 2 minutes. From gas exchange parameters and heart rate and lactate values, ventilatory anaerobic thresholds, heart rate deflection point and the onset of blood lactate accumulation were calculated. CP was determined with linear work-time method using 3 loads. The subjects exercised until they could no longer maintain a cadence above 24 rpm at their CP and exercise time to exhaustion was determined. RESULTS: CP was lower than the power output corresponding to VO2max, higher than the power outputs corresponding to anaerobic threshold. CP was correlated with VO2max and anaerobic threshold. Exercise time to exhaustion and work at CP were not correlated with VO2max and anaerobic threshold. CONCLUSIONS: Because of the correlations of the CP with VO2max and anaerobic threshold and no correlation of exercise time to exhaustion and work at the CP with these parameters, we conclude that exercise time to exhaustion and work at the CP cannot be used as an index in the determination of endurance.

Adolescent↗