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At least 631 records · Page 35Linked to original sources
PubMed1987

[Metastatic skipping in the bone marrow (skip metastases) in osteosarcoma. Frequency and clinical implications?].

The existence of skip metastases in osteosarcoma, a particular type of spread of this tumor, has been questioned. We have reviewed 229 cases of osteosarcomas and found two instances of skip metastases. In both the histological appearance of the metastatic forms and the primary tumor were identical. Our experience suggests that skip metastases are less frequent than originally proposed by Enneking and we discuss the possible clinical implications of our findings.

Adolescent↗
PubMed1986

Titanium fibermetal segmental replacement prostheses. A radiographic analysis and review of current status.

Thirteen patients with titanium fibermetal segmental bone/joint prostheses at a minimum follow-up period of six months were reviewed. Detailed radiographic data were analyzed quantitatively in terms of stem/bone interface radiolucency and bone bridging over the segmental portion of the prosthesis at predefined zones. Although stem radiolucent lines were common in this series, only one case had clinical loosening and required reoperation. There were two cases of stem fracture; one achieved extracortical bone union without revision, and the other case required implant removal and revision. Analysis of the retrieved specimen revealed histologic evidence of bony ingrowth. The use of a long side plate for initial implant fixation might have been partially responsible for this complication because of inhibition of new bone formation over the porous-coated segment. Sequential study of radiograms at different follow-up time periods with the same zonal analysis criteria revealed that no progression of radiolucency occurred at the bone/prosthesis interface, and bone formation over the segmental portion either increased or stabilized with time. The patients' functional results and implant performance seemed to indicate that the porous-coated segmental prosthetic system was effective in bridging skeletal/joint defects. However, further improvements are needed in prosthetic design and implant quality control in order to minimize device-related complications.

Adolescent↗
PubMedDate not supplied

The closed cryosurgical treatment of giant cell tumor.

Twelve patients with giant cell tumor (GCT) treated by the closed method of cryotherapy along with curettage and bone grafting were reviewed retrospectively. Follow-up examinations ranged from two years and two months to 11 years. There was one osseous and one soft-tissue recurrence. There were no thermally related soft-tissue complications. Five patients suffered six postoperative pathologic fractures. Joint function was well preserved in ten of 12 patients, although five patients have varying degrees of joint pain or instability. Closed cryotherapy, curettage, and bone grafting are effective in the treatment of GCT. Special attention to surgical approach, controlled freezing, bone grafting technique, and a supervised rehabilitation program will minimize the incidence of postoperative pathologic fracture and maximize joint function.

Adolescent↗