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At least 631 records · Page 35Linked to original sources
PubMed1977

Surgery for the post-cricoid carcinoma. Report on 23 cases in which replacement by stomach was attempted.

A report on 23 cases of post-cricoid carcinoma treated by pharyngolaryngectomy and pharyngogastric anastomosis. The results, complications, and causes of death are reported. The series showed that, when the tumor recurred it was in the regional lymph nodes and in only one case was the primary site involved. Metastasis occurred elsewhere only after regional node involvement.

Carcinoma↗
PubMed1982

[Histological findings of 15 excised arytenoid cartilages after long-lasting recurrent nerve paralysis (author's transl)].

Histological findings of 15 excised arytenoid cartilages are reported. In all cases there was a long-term recurrent nerve paralysis without additional inflammatory disease. In one of the cases there was fibrosed ankylosis of the cricoarytenoid joint. This is the first report made on the histological findings of the arytenoid cartilage in cases of paralysis. It is confirmed that there is a difference in the joint pathology in cases of immobility due to inflammatory conditions and pure non inflammatory recurrent paralysis. The fixation caused by arthritis of the joint has relatively poor prognosis after surgery while if fixation is due to recurrent nerve paralysis the chances of recovery are good in long-term paralysis.

Ankylosis↗
PubMed1999

[The reconstruction of laryngeal function in subtotal laryngectomy with preservation of arytenoid cartilage].

OBJECTIVE: To evaluate subtotal laryngectomy with preservation of arytenoid cartilage to reconstruct laryngeal function in T3 glottic or supraglottic laryngeal cancer. METHODS: Subtotal laryngectomy with preservation of arytenoid cartilage to reconstruct laryngeal function was reviewed in 20 patients with T3 laryngeal cancer(3 cases with glottic cancer and 17 cases with supraglottic cancer). Recurrent laryngeal nerve was preserved during surgery. The mucous membranes between cricoid cartilage and pharynx were sewed up accordingly. RESULTS: All patients had restored phonation and swallowing functions. The 3- and 5-year survival rates were 94.1% and 91.8% respectively. Decannulation rate was 95.0%. CONCLUSION: Subtotal laryngectomy with preservation of arytenoid cartilage is recommended for T3 laryngeal cancer.

Aged↗
PubMed1975

The use of the inferior cornu of the thyroid cartilage in identifying the recurrent laryngeal nerve.

The inferior thyroid artery, traditionally used as a guide in identifying the recurrent laryngeal nerve, is not wholly reliable because of two factors which affect the constancy of the relation between nerve and artery. One is the variability of the anatomic pattern of tbe inferior thyroid artery, and the other is the occasional incidence of a nonrecurrent inferior laryngeal nerve. In a study of 500 recurrent laryngeal nerves, the inferior cornu of the thyroid cartilage was more reliable than the inferior thyroid artery in identifying the recurrent laryngeal nerve. The anatomic relation between the recurrent laryngeal nerve and the inferior cornu of the thyroid cartilage was constant in all patients, except those in whom there was displacement of the nerve resulting from lesions of the thyroid or the parathyroid glands. Operations upon the neck require understanding of the anatomic characteristics of the recurrent laryngeal nerve and of possible involvement of the nerve with the pathologic process involvement of the nerve with the pathologic process as well as fastidious operative technique.

Humans↗
PubMed2006

Cartilage aggrecan undergoes significant compositional and structural alterations during laryngeal cancer.

Aggrecan is a key component of cartilage and is responsible for the integrity and function of the tissue. In this study, the content of aggrecan and its structural modifications in adjacent to cancer apparently normal cartilages (AANCs) from various stages of laryngeal squamous cell carcinoma (LSCC) were investigated. Our data demonstrated a stage-related loss of aggregable aggrecan in AANCs, compared to the healthy laryngeal cartilage (HLC), which was excessive in advanced stages of disease. On aggregable aggrecan level, AANCs were characterized by significant compositional and structural modifications, the extent of which was closely related with the stage of LSCC. Four concrete subpopulations of aggregable molecules with particular physicochemical characteristics were identified with a strong tendency to prevail subpopulations of molecules of lower hydrodynamic sizes with increasing LSCC stage. These findings demonstrated that the cleavage of aggregable aggrecan occurred in concrete peptide bonds within the CS-1 and CS-2 attachment domains. These significant alterations were closely associated with the process of cartilage destruction, indicating the crucial role of aggrecan during LSCC.

Adult↗