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At least 631 records · Page 35Linked to original sources
PubMed1984

Contact and photocontact allergy to sunscreens.

Patch and photopatch test studies in 23 patients with reactions to sunscreen preparations revealed 17 photopatch and 38 patch test-positive reactions. The offending allergens could be traced in 18 of the 23 patients. Allergy to PABA was demonstrated in 11 patients, 5 of whom had photocontact allergy. Photocontact allergy to oxybenzone was seen in 3 patients, while 8 were sensitive to cinnamates, and 2 of these had a photocontact allergy. Six patients were sensitive to the PABA-derivatives octyldimethyl-PABA and amyldimethyl-PABA and the ester glyceryl PABA, 2 of whom had a photocontact allergy. None of the 3 patients with benzocaine sensitivity, including 2 with a photocontact allergy, reacted to the PABA-ester. Eight patients were sensitive to different cinnamates, including 2 cases of photocontact allergy. In one patient sensitivity to two azo-naphthol dyes, contained in a sunscreen preparation, was confirmed. Five other patients had positive skin test reactions to different sunscreen preparations but the offending allergen could not be traced. Thirteen of the 23 patients had chronic light sensitive disorders such as polymorphic light eruption (PMLE) or persistent light reactivity (PLR). Sunscreen sensitivity appears to be more common than previously reported.

4-Aminobenzoic Acid↗
PubMed1984

Nail changes secondary to systemic drugs or ingestants.

Systemic drugs often affect the nails. These changes range from mild pigmentation abnormalities to nail shedding and matrix scarring. The purpose of this article is to provide a handy reference for the physician who is confronted with nail disorders that may be due to systemic drugs or ingestants.

4-Aminobenzoic Acid↗
PubMed1986

Porphyria cutanea tarda. Diagnosis, management, and differentiation from other hepatic porphyrias.

Porphyria cutanea tarda is a photocutaneous syndrome characterized clinically by cutaneous fragility, bullae, hypertrichosis, pigmentary changes, and sclerodermoid plaques and characterized biochemically by hepatic overproduction and storage of excessive amounts of porphyrins. Porphyria cutanea tarda, the most common disorder of porphyrin metabolism, must be differentiated from variegate porphyria, hereditary coproporphyria, bullous dermatosis of hemodialysis, and drug-related pseudoporphyria.

Biopsy↗
PubMed1963

CURRENT CONCEPTS IN DERMATOLOGY. II. THE SKIN AND SYSTEMIC DISEASE.

Many systemic diseases have cutaneous manifestations. In some diseases skin involvement is the predominant factor (Behçet's syndrome, urticaria pigmentosa, discoid lupus erythematosus and pseudoxanthoma elasticum); in others the skin manifestations, when present, are an important part of the condition (sarcoidosis, systemic lupus erythematosus, hypersensitivity angiitis, porphyria). This report includes descriptions of and comments on these cutaneous manifestations. Erythema nodosum and erythema multiforme are reaction patterns of the skin and mucous membrane which may have many causes. The relationship between discoid and systemic lupus erythematosus is discussed. There is little doubt that these are variations of the same basic disease process, even though the prognoses are very different.

Avitaminosis↗
PubMed2004

Juvenile spring eruption: clinicopathologic features and phototesting results in 4 cases.

Juvenile spring eruption is a distinct photodermatosis characterized by the development of papules and vesicles on light-exposed areas of the ears usually in the early springtime. It primarily affects boys and young men, and has a tendency to occur in the form of small epidemics. We report a similar outbreak in separate groups of soldiers who were performing military exercises during cold and sunny weather of a midwinter season. The clinicopathologic features and phototesting results are described in 4 of these cases. All patients showed normal erythemal responses to monochromator phototesting with UV and visible wave bands. Photoprovative testing with repeated daily exposures of the ears to a broadband UVA source provoked diffuse erythema and itching in 1 case, whereas similar photoprovocation of a nonaffected area, ie, the flexor surface of the forearm, in 2 patients did not yield a skin reaction. Although the cause of juvenile spring eruption is not known, our observations further strengthen the hypothesis that the disorder is a localized variant of polymorphous light eruption.

Adolescent↗
PubMed1992

Genetic disorders of the skin and eye.

This article discusses some of the most uncommon diseases ever seen by the ophthalmologist or dermatologist. Some of these conditions can cause irreparable eye damage if not recognized and treated early after their inception.

Eye Diseases, Hereditary↗
PubMed2000

Photo-accentuated eruption and vascular deposits of immunoglobulin A associated with hepatitis A virus infection.

Skin rash associated with hepatitis A virus infection has rarely been reported. We describe a patient with hepatitis A virus infection who presented a rubelliform rash markedly accentuated in sun-exposed areas; direct immunofluorescence studies of the lesion revealed immunoglobulin (Ig) A deposition on the endothelial cells in the upper dermis. Oral rechallenge tests of the previously administered drugs failed to reproduce the eruption. The preferential setting of immune complexes containing IgA at sites of sun exposure and sunlight as a triggering factor might have been responsible for the development of the eruption in this patient. Eruptions associated with hepatitis A virus infections may be more frequent than commonly thought. Because of difficulty to exclude the possibility of drug eruptions, these cases might have been overlooked. In patients with such a disorder, a careful clinical workup such as IgM antibodies for hepatitis A virus at diagnosis and during follow-up is especially recommended.

Adult↗
PubMed1981

Berloque dermatitis - a continuing cosmetic problem.

Despite the decline in the incidence of berloque dermatitis during the past decade, milder cases resulting from the presence of relatively small quantities of bergapten in perfumed cosmetics continue to occur. The resultant hyperpigmentation may have an atypical presentation leading to error in diagnosis. In addition, the condition can sometimes induce or aggravate melasma and may be responsible for other pigmentary disorders of the face and neck of questionable etiology such as poikiloderma of Civatte, Riehl's melanosis and pigmented peribuccal erythema of Brocq.

5-Methoxypsoralen↗
PubMed1984

Noninfectious skin diseases of cattle.

The noninfectious bovine skin disorders can best be summarized by four factors: environmental, nutritional, congenital, and neoplastic. This article has attempted to address the etiology, treatment, and prevention of most of these noninfectious diseases.

Animals↗
PubMed1990

[Hyperpigmentation of the face].

A 49-year-old male patient is presented, who developed hyperpigmented macules on the face. An exact classification of the disorder was not possible on the basis of anamnestic data, histology and electron microscopy. An attempt was made to differentiate it from other known dyschromias of the face.

Dermabrasion↗