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At least 631 records · Page 35Linked to original sources

PubMed1991

[Reversibility of visual field defects in primary open-angle glaucoma].

The course of the glaucomatous visual field seems to be best followed by computerized perimetry which allows threshold evaluation in a great number of locations and statistical analysis of the results. To determine the visual field defect reversibility, 16 patients (27 eyes) affected by uncontrolled open-angle glaucoma underwent visual field analysis before and after prescription of a new medical therapy. To avoid the "learning effect" and to decrease the influence of the heterogeneous component of long-term fluctuation, the visual field examination was repeated within 48 hours whenever a change in sensitivity was detected. In addition a total of 10 normal eyes in 10 patients were tested as a control group. A statistically significant threshold improvement was demonstrable after one week of therapy in 31.7% of the eyes.

Adult↗

PubMed2007

Classifying patterns of localized glaucomatous visual field defects on automated perimetry.

AIM: To classify the classic patterns of glaucomatous visual field defects on automated perimetry and to study their proximity to fixation. STUDY DESIGN: Cross-sectional observational study. MATERIALS AND METHODS: About 1120 full threshold 30-2 reliable visual fields of glaucoma patients were analyzed by 2 glaucomatologists. Classically described patterns of visual field defects were identified on the pattern deviation plot and definitions proposed. Interreader agreement between 3 independent (not involved in the classification) readers was determined. Proximity to fixation of the different patterns was assessed. RESULTS: Interreader agreement with 3 readers was found to be 93% or more between any 2 readers using the present system of classification. Central fixation was seen to be involved in 45% of the glaucomatous visual field defects studied overall. CONCLUSIONS: The proposed definitions of topographical glaucomatous field defects based on the pattern deviation probability plot are simple to use in clinical practice with good interreader agreement.

Cross-Sectional Studies↗

PubMed1993

The effectivity of Fresnel prisms for visual field enhancement.

An objective method for placement of Fresnel prisms has been used to enhance constricted visual fields at the Eastern Blind Rehabilitation Center in West Haven, CT since 1975. To study the effectiveness of this method, 22 patients fitted with prisms since 1986 participated in a survey regarding their level of satisfaction with the prisms. Nineteen out of 22 patients continued to wear the prisms successfully, resulting in a retention rate of 86.3 percent. Of those still wearing the prisms, their reported overall satisfaction level averaged 3.63 on a scale of 1-4 (4 representing very satisfied). The reported satisfaction levels of the patients wearing the prisms were statistically analyzed with respect to pathology, months of wear, age of the patient, binocular versus monocular fitting, size of the residual field, visual acuity, the power of the prism used, and ocular rotation to enter the prism. No significant predictive value was found with any of these variables in trying to determine the level of satisfaction. However, this may be due to the small sample size. These same variables were used in comparing the patients who continued to wear the prisms with the patients who had discontinued prism use. None of these variables was found to be significant in predicting a successful outcome, possibly in part to small sample size, and the low number of unsuccessful patients. In an effort to make improvements on the existing methods being used for field enhancement, questions were asked regarding technical use of the prisms, mobility with the prisms, the spectacle carrier lens, and the maintenance of the prisms.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMed2005

Useful visual field reduction as a function of age and risk of accident in simulated car driving.

PURPOSE: To study the relationships between the reduction of the useful visual field, age, and driving performance. METHODS: Forty-eight subjects, aged from 23 to 77 years performed a test to evaluate the size of their useful visual fields. The test involved the detection and localization of peripheral signals that could appear in an area of 70 degrees of visual angle. The subjects then performed a simulated car-driving task involving the management of a situation that could lead to an accident. RESULTS: The analysis of the data revealed that the ability to process peripheral signals and simulated driving performance (vehicle speed) deteriorate with age. Simulated driving performance and useful visual field measurement have been analyzed jointly. The results indicate that the reduction of the useful visual field, estimated using a target-localization task, is related to the individual's ability to manage the simulated driving situation (correlation coefficient with speed = -0.43 and with reaction time for avoidance of a mobile obstacle = +0.30) and the deterioration of the useful visual field estimated using a target detection task is related only to vehicle speed (correlation coefficient = -0.32). CONCLUSIONS: The adoption of a lower speed by the drivers with a reduced visual field (the elderly ones) is probably an adaptation strategy to process the peripheral information. All useful visual field measurements do not seem to be equivalent to estimate the ability to process information relative to the mobile obstacle. The risk of collision should be estimated only with a useful visual field test using a target localization task.

Accidents, Traffic↗

PubMed2000

Intraocular pressure and progression of glaucomatous visual field loss.

PURPOSE: To evaluate the relationship between intraocular pressure and visual field progression in patients with primary open-angle glaucoma. METHODS: We prospectively followed 113 patients with early to moderate glaucomatous field damage. Conventional automated static perimetry, high-pass resolution perimetry, and intraocular pressure measurements were carried out at 6-month intervals. The mean and the highest intraocular pressure in the follow-up were compared in stable and progressing patients with each perimetric technique. RESULTS: The mean (+/- SD) follow-up was 4.5 +/- 0.9 years. The mean (+/- SD) intraocular pressure in patients remaining stable with conventional perimetry [18.2 +/- 3.3 mm Hg, n = 81 (71.7%)] was not significantly different (P =.65) from those in whom it progressed (17.9 +/- 3.3 mm Hg, n = 32 [28.3%]). The mean intraocular pressure in patients remaining stable with high-pass resolution perimetry (17. 9 +/- 3.5 mm Hg, n = 63 [55.8%]) was not significantly different (P =.33) from those in whom it progressed (18.5 +/- 3.0 mm Hg, n = 50 [44.2%]). The mean (+/- SD) of the highest (single or three highest) pressure during follow-up for stable and progressing patients with conventional perimetry was not significantly different (22.6 +/- 5.0 and 23.0 +/- 4.6 mm Hg, respectively, P =.76). However, for high-pass resolution perimetry, the difference was highly significant (21.6 +/- 4.5 and 24.1 +/- 4.9 mm Hg, respectively, P <. 01). Furthermore, patients who progressed with high-pass resolution perimetry had more damaged baseline fields compared with those who remained stable (P <.01). CONCLUSIONS: The mean level of intraocular pressure does not differentiate glaucoma patients with progressive visual field loss from ones who remained stable. Baseline visual field status and peak intraocular pressure of patients who progress with high-pass resolution perimetry are significantly different from those who remain stable.

Adolescent↗

PubMed2001

The value of electrophysiology results in patients with epilepsy and vigabatrin associated visual field loss.

PURPOSE: To determine the value of electrophysiological findings in patients with temporal lobe epilepsy and to relate these findings to the amount of concentric contraction of the visual field and the use of vigabatrin. METHODS: Electro-retinograms and electro-oculograms were done on 30 patients, operated for temporal lobe epilepsy. The patients were divided into three groups: (A) concentric contraction of the visual field associated with a history of vigabatrin medication (15 patients), (B) normal visual field with vigabatrin use (11 patients) and (C) normal visual field without vigabatrin medication (4 patients). RESULTS: Electrophysiological abnormalities were found in 50% of the patients in group A. The Arden ratio of the EOG was lowered in 57%. Abnormalities in the ERG were found: b-wave implicit time photopic F was prolonged (50%), b-wave amplitudes scotopic B (53%), C (73%) and G (50%) and photopic H (50%) were diminished. The amount of visual field loss and the total dose of vigabatrin used, showed only slight correlation with the ERG and EOG. The use of vigabatrin during the ERG and EOG recording in group A, gave a higher b-wave amplitude scotopic G in 64% of cases. The a-wave implicit times scotopic G (73%) and photopic G (59%) and H (73%) were shortened in group B. CONCLUSION: EOG was abnormal in 57% in group A. ERG abnormalities could only be found in 50% of group A, mainly in the inner retina. Since also the total dose of vigabatrin and the amount of visual field loss did not really show a correlation with the electrophysiological findings and results of literature are not unanimous, electrophysiology does not appear at present to be a good method to detect patients with, or at risk of, vigabatrin associated visual field loss. Regularly performed visual field examination remains the cornerstone in screening.

Adult↗

PubMed1988

Evaluation of corrected loss variance as a visual field index. I. CLV exceeds RMS in discriminating between glaucoma-suspect patients with no loss of visual sensitivity and normal observers.

Octopus visual fields were compared for three groups of patients: (1) diagnosed glaucoma patients; (2) glaucoma-suspect patients, and (3) control observers. Four visual field indices were analyzed for each visual field: mean sensitivity, short-term fluctuation (root mean square), mean defect, and corrected loss variance. Among the four indices, corrected loss variance was the only index that discriminated the glaucoma-suspect group from the control group, while, as expected, the glaucoma group differed from the other two study groups for all four indices. These data support the view that corrected loss variance may provide highly sensitive information on which to base an early clinical diagnosis of glaucoma in patients who do not demonstrate traditional field loss.

Adult↗

PubMed1996

[Visual field defect following macular hole surgery].

We report three patients with inferotemporal visual field defect following pars plana vitrectomy for idiopathic macular hole. Two patients complained of the visual field defect early in the postoperative period, and one patient was asymptomatic but showed abnormalities in perimetry. The visual field defect remained unchanged during a follow-up study of 4 to 12 months. It is possible that inadvertent damage to the optic nerve associated with air/ fluid exchange or hyaloid membrane stripping caused the characteristic visual field defect.

Female↗

PubMed1986

Eccentricity-dependent residual target detection in visual field defects.

Lesions in the postgeniculate part of the visual system lead to visual field defects in the corresponding parts of the contralateral visual field. In some patients these field defects, though blind according to perimetry, have been observed to still be sensitive to visual stimulation. This report is based on studies of five such patients, whose ability to detect a small visual target presented tachistoscopically within the blind field was tested. Receiver-Operating-Characteristic curves were measured for three different retinal positions: a relatively central one, an eccentric one, and one within the natural Blind Spot that serves as a control. Results show that the four patients who could detect the target did so exclusively at the eccentric position.

Aged↗

PubMed2002

Progression of visual field loss in untreated glaucoma patients and glaucoma suspects in St. Lucia, West Indies.

PURPOSE: A 1986-1987 survey found 8.8% prevalence of open-angle glaucoma in the black population of St. Lucia, West Indies. This follow-up study assessed visual field loss progression in untreated glaucoma patients and glaucoma suspects 10 years later. DESIGN: Cohort study. METHODS: Subjects were 205 glaucoma patients and suspects; 1987 data included age, sex, visual acuity, and visual fields measured by automated threshold perimetry (Humphrey C 30-2 test), and 1997 data included intraocular pressure, visual acuity, and visual fields measured by the same test. Exclusion criteria included field unreliability, field improvement due to vision improvement, nonglaucomatous vision deterioration, glaucoma treatment since 1988, and scoring of a visual field as end stage in 1987. Visual fields were scored by algorithms for the Advanced Glaucoma Intervention Study (AGIS) and Collaborative Initial Glaucoma Treatment Study (CIGTS). RESULTS: By AGIS criteria, 55% of 146 right eyes and 52% of 141 left eyes showed progression of visual field loss. In linear regressions, progression severity was unassociated with sex, intraocular pressure, or baseline visual field score, but was positively associated with age (P <.001, right; P =.002, left). The cumulative probability of reaching end stage in 10 years in at least one eye was approximately 16% by AGIS criteria. By CIGTS criteria, 73% of 146 right eyes and 72% of 141 left eyes progressed. CONCLUSIONS: These data provide a unique opportunity to study progression of untreated glaucoma. The percentage of eyes showing visual field loss progression and the percentage reaching end stage were considerably higher than in studies of visual field progression in treated eyes.

Adult↗

PubMedDate not supplied

A reassessment of the lower visual field map in striate-recipient lateral suprasylvian cortex.

Lateral suprasylvian visual cortex in the cat has been studied extensively, but its retinotopic organization remains controversial. Although some investigators have divided this region into many distinct areas, others have argued for a simpler organization. A clear understanding of the region's retinotopic organization is important in order to define distinct areas that are likely to subserve unique visual functions. We therefore reexamined the map of the lower visual field in the striate-recipient region of lateral suprasylvian cortex, a region we refer to as the lateral suprasylvian area, LS. A dual mapping approach was used. First, receptive fields were plotted at numerous locations along closely spaced electrode penetrations; second, different anterograde tracers were injected at retinotopically identified sites in area 17, yielding patches of label in LS. To visualize the resulting data, suprasylvian cortex was flattened with the aid of a computer. Global features of the map reported in many earlier studies were confirmed. Central visual field was represented posteriorly, and elevations generally shifted downward as one moved anteriorly. Often (though not always) there was a progression from peripheral locations towards the vertical meridian as the electrode moved down the medial suprasylvian bank. The map had some remarkable characteristics not previously reported in any map in the cat. The vertical meridian's representation was split into two pieces, separated by a gap, and both pieces were partially internalized within the map. Horizontal meridian occupied the gap. The area centralis usually had a dual representation along the posterior boundary of the lower field representation, and other fragments of visual field were duplicated as well. Finally, magnification appeared to change abruptly and unexpectedly, so that compressed regions of representation adjoined expanded regions. Despite its complexity, we found the map to be more orderly than previously thought. There was no clearcut retinotopic basis on which to subdivide LS's lower field representation into distinct areas.

Animals↗

PubMed1991

Pituitary tumor volume as a predictor of postoperative visual field recovery. Quantitative analysis using automated static perimetry and computed tomography morphometry.

We attempted to define the relationship between the volume of pituitary adenomas and postoperative visual field recovery. Fourteen consecutive patients (27 eyes) were studied who presented with visual complaints and who were confirmed to have pituitary macroadenomas at the time of resection. For each eye, preoperative visual field loss in each quadrant as well as whole field loss were analyzed. Tumor volume was determined from computed tomography scans by summing serial axial sections. Statistically significant correlations (p less than 0.05) of preoperative superonasal and whole visual field loss with tumor volume were found. Postoperative visual field recovery was determined for each patient by subtracting the postoperative visual field loss from the preoperative field loss. Postoperative inferonasal field recovery was significantly correlated (p less than 0.01) with whole tumor volume, with markedly greater recovery in patients with tumor volumes of 5 cc or less. In general, tumor volume proved to be a poor predictor of postoperative visual field recovery.

Adenoma↗

PubMed1991

Subjective detection of visual field defects using home TV set.

The usefulness of the noise-field spontaneously generated on a home television screen for subjective perception of visual field defects was studied in 196 eyes of ocular hypertensive or normal subjects, 166 eyes with primary open angle glaucoma and 124 eyes with low-tension glaucoma. All subjects had never perceived their field defects. In 290 glaucoma eyes, including 71 eyes of early glaucoma, 265 eyes (91.4%) could perceive abnormality of the noise-field which corresponded to visual field defects confirmed by static perimetry. In 6 normal eyes abnormality of the noise-field was perceived at the blind spot. The sensitivity and specificity of the test was 91% and 97%, respectively. The time required for testing one eye was 3-5 seconds. The results indicate that the Noise-Field Test using a home television set can be an excellent method for subjective perception of visual field defects, and can also be used for glaucoma screening.

Fundus Oculi↗

PubMed1988

[Evaluation of the central visual field by the Friedmann Mark I analyzer and color vision in 85 patients with multiple sclerosis. Correlation with visual evoked potentials in 50 cases].

Analysis of the visual field using Friedmann's analyser Mark I and color study in 85 multiple sclerosis patients. Static perimetry of the central visual field and test batteries (Ishihara plates, 15 Hue Standard, 15 Hue of Lanthony) for acquired color vision defects were performed in 85 multiple sclerosis patients (61 definite, 12 probable, 12 possible cases). Results in patients were compared to data obtained in 53 control subjects matched for age. 64% of the 85 patients and 52% of 48 patients with no history of optic nevritis showed visual field abnormalities and/or color vision defects. Comparison with VEP was available in 50 patients. While 10 patients had abnormal VEP and normal static perimetry and coloration tests, 5 patients had the reverse findings.

Adolescent↗

PubMedDate not supplied

[What is the visual field?].

Eye movements were recorded in the course of visual field determination. The behaviour of the eye is various in different persons, defying any rule, except, contrary to the definition of the visual field, it does not remain immobile but executes one or more saccades. Discussing the results the authors present a new concept of the visual field.

Adult↗

PubMed2003

[Vigabatrin and visual field defects. A Danish material with evaluation of different screening methods].

INTRODUCTION: The aim of the study was to assess the prevalence of visual field constriction in a consecutive, unselected series of patients in the Copenhagen area treated with vigabatrin for severe epilepsy, and further to assess appropriate screening techniques for detecting such visual field defects. MATERIAL AND METHODS: During 1999, 36 vigabatrin-treated patients (aged 13-67) referred to the eye clinic, had a full ophthalmic examination. Routine visual field testing by means of a) finger movements and b) a tangent screen was supplemented by c) manual kinetic Goldmann perimetry and d) automated static threshold profile perimetry (Octopus). RESULTS: Of the 31 subjects accepted for entry, 80% showed some degree of visual field constriction. The affection was regarded as slight in 15 cases, moderate in seven, and severe in four. Both kinetic Goldmann and static computerised perimetry disclosed the peripheral defects in those affected. By Goldmann perimetry, it appeared as a smooth narrowing of outer visual field borders, whereas Octopus demonstrated a less regular, more scattered loss of sensitivity. DISCUSSION: Eighty per cent with peripheral field affection is among the highest reported frequencies in a vigabatrin-treated series of patients so far. An association with a cumulated dose of the drug was demonstrated. Visual field testing by finger movements and tangent screen evaluation will not reveal the initial peripheral losses of the visual field. For this purpose, we found manual kinetic Goldmann perimetry a valid alternative to modern computerised perimetric techniques. Goldmann takes less time, makes the co-operation of the patient easier, and the interpretation is simple.

Adolescent↗

PubMed1996

Visual-field deficits associated with proton beam irradiation for parapapillary choroidal melanoma.

PURPOSE: A large series of patients treated with proton irradiation for parapapillary choroidal melanoma were reviewed retrospectively to determine the frequency of radiation papillopathy and visual-field loss after treatment. METHODS: Among 249 patients with proton irradiation for parapapillary choroidal melanoma, the authors identified 59 patients who had visual-field testing performed before treatment and at least 18 months after treatment. The visual fields, color fundus photographs, and charts were reviewed to determine the prevalence of radiation papillopathy and visual-field loss after treatment. RESULTS: Nineteen of the 59 patients reviewed (31%) received a clinical diagnosis of radiation papillopathy. Progressive visual-field loss, defined as enlargement of absolute scotoma of greater than [corrected] or equal to 30 degrees as compared with the pretreatment visual field, was noted in 67% of patients with radiation papillopathy and 73% of patients without papillopathy. In both groups, visual-field loss correlated with the area of the retina predicted to be exposed to irradiation in the majority of patients. CONCLUSIONS: Progressive visual-field loss is common after proton irradiation for parapapillary choroidal melanoma. However, the scotoma usually correlates with the area of the retina exposed to irradiation. The development of radiation papillopathy does not appear to be associated with additional visual-field defects in most cases.

Adult↗

PubMed1997

Correlation between the visual field indices and Heidelberg retina tomograph parameters.

PURPOSE: We wished to determine whether a relationship exists between Heidelberg retina tomograph (HRT) parameters and the visual field indices. METHODS: One eye was randomly chosen from 59 normal patients [normal visual field and normal optic nerve head (ONH) and intraocular pressure (IOP) < 21 mm Hg], 64 ocular hypertensive patients (normal visual field and normal OHN and IOP > 22 mm Hg), 124 high-tension glaucoma patients (abnormal visual field and/or abnormal optic nerve and IOP > 22 mm Hg) and 47 low-tension glaucoma patients (abnormal visual field and or optic disc and IOP < 21 mm Hg). All the patients were examined with Humphrey Perimeter, program 30-2, and HRT. Findings were assessed by analysis of variance, Pearson's correlation coefficient, and multiple linear regression. RESULTS: Among all subjects, we noted a statistically significant correlation (Pearson's r, p < 0.001) between cup area, cup/disc area ratio, rim area, rim volume, cup shape measure, and retinal nerve fiber layer cross-section area with mean deviation and corrected pattern SD. Multiple linear regression analysis demonstrated that rim area was the most important predictor of mean deviation and corrected pattern SD. CONCLUSIONS: The presence of significant correlations between some HRT parameters, such as rim area and cup shape measure and visual field indices, suggests that these HRT parameters could be good indicators of the degree of glaucomatous ONH damage.

Glaucoma, Open-Angle↗