PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “BENACTYZINE”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 649 records · Page 36Linked to original sources
PubMedDate not supplied

[Morphofunctional changes in the sex gland of rats during stimulation and blockade of the M- and N-cholinoreactive systems].

The cholinergic agents arecolin, nicotin, amizil and etherofen induced morphofunctional changes in the testes as shown by experiments on white male rats. The drugs in a dose of 1 mg/kg stimulated hormonogenesis of the testicle. The cholinoblockers amizil and etherofen in a dose of 5 mg/kg strongly inhibited androgenic production. All the substances disturbed spermatogenesis, whose intensity depended on the action and doses of the drugs.

Animals↗
PubMedDate not supplied

[Effect of cholinolytics on the functional lability of the visual analyzer in cats].

The effect of aminoethers of derivates of glycolic acid (glipine and amizil) in doses of 0.1--5 mg/kg and of derivates of acetic acid (diphacyl and thropacin) in doses of 10--40 mg/kg on bioelectrical activity of the retina was studied in experiments on 10 intact cats. To control the effect of cholinolytics, electrodes were chronically implanted in the visual cortex and EEG ws recorded. It was noted that the frequency of white, yellow, green and blue photic stimuli is reproduced on ERG within the range from 1 to 23 c/s both before the administration of cholinolytics and during their action in all of the used doses. Flash rhythm reproduction was not disturbed (in spite of an increase in the waves' amplitudes in the retinal background bioelectrical activity) following administration of cholinolytic substances. All cholinolytics in all of the studied doses caused in the EEG of the visual cortex an increase in waves' amplitude, i. e. a synchronization.

Animals↗
PubMedDate not supplied

[Reproduction of "passive" avoidance in rats by administering pharmacologic agents].

In experiments on rats learned to passive avoidance reaction in one trial with subsequent administration of electroconvulsive shock (two hours after learning), the influence of different factors on the retrieval of the lost reaction was tested after three days. The greatest restoring capacity was exhibited by a non-specific reminding agent, the bell, gamma-amino-butyric acid (200 mg/kg) and etimizol (1.5 mg/kg). In animals with a preserved reaction, a number of pharmacological agents impaired retrieval of the habit (caffeine 5 mg/kg, carbocholine 0.01 mg/kg and metamizil 0.5 mg/kg). Optimal conditions for the restoration of the lost reaction were formed by etimizol and gamma-aminobutyric acid. Cholinergic mechanisms play a certain role in the functioning of the retrieval apparatus.

Amnesia↗