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Leprosy in Cuba.

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Adolescent↗

[Microbiological processes in the mromictic lake Vae de San Juan in Cuba].

The lake was studied in April and July of 1973. Gleothece prevailed in mixolimnion and green sulphur bacterium Pelodyction phaeum in the layer of pink water down to 10 m. The production of photosynthetic suphlur bacteria comprises 3% of the production of algae. Sulphate reduction takes place mainly in water beyond the layer of sulphur bacteria. The content of hydrogen sulphide in monimolimnion is 104 mg/litre. Bacteria utilize, at the account of photosynthesis, 40% of produced hydrogen sulphide. Three maxima in the bacterial content in water have been registered: (a) at a depth of 7 m; (b) in the layer of pink water, at a depth of 10 m; (c) at the bottom. Total mineralization and electroconductance of water at the bottom are higher by a factor of 6 than those at the surface. Destruction of organic substance is higher than its production a little.

Bacteria↗

[A chromatographic analysis of the Mycobacterium tuberculosis strains isolated from an outbreak in HIV patients in Cuba].

A group of strains of Mycobacterium tuberculosis isolated from an outbreak in HIV-infected patients was studied by chromatographic techniques. A group of strains of M. Tuberculosis from symptomatic respiratory patients (SR+ 14) and patterns strains from the laboratory collection were used as a reference aimed at making a qualitative comparison of the chromatographic patterns described by the strains isolated from patients. The chromatographic profiles of the strains isolated from patients (SR+) and fro HIV+ were obtained and compared by thin layer chromatography (TLC). Each of the present fatty acids was identified by using the gas chromatography technique (GC) coupled to mass spectrum analysis. All the studied strains were classified as Mycobacterium tuberculosis. According to the results attained, the usefulness of the chromatographic techniques as alternative techniques for the mycobacterial diagnosis is demonstrated.

AIDS-Related Opportunistic Infections↗

[The management of tuberculosis in the Republic of Cuba].

The essential aspects for the management of tuberculosis surveillance and control are described to propitiate their divulgation among to health professionals. Since 1970 there is an integrated program under way within the health services based on the localization of cases by the bacilloscopic examination and the sputum culture in symptomatic respiratory patients, the ambulatory controlled treatment, the investigation of the contacts of the notified cases, including the chemoprophylaxis with isoniacide, and the BCG vaccination to newborns. In 1995, the percentage of symptomatic patients detected at the general medicine offices was of 0.7%, whereas the percentage of the first bacilloscopy performed among the symptomatic individuals was of 78.6%, 99.5% of the detected contacts were investigated. 37.9% of the new cases were diagnosed at the primary health care level. After a decreasing trend maintained from 1979 to 1991, mortality has increased from 50 deaths (0.5 x 10(5)) in 1991 to 157 (1.4 x 10(5)) in 1995, and the incidence rose from 503 (4.7 x 10(5)) in 1991 to 1,574 (14.3 x 10(5)) in 1994, and to 1,553 (14.0 x 10(5)) in 1995, which suggests that the increase observed during the last 6 years begins to stop. The primary resistance to tuberculostatics was of 3.5% in 1992-1995, and of 11.5% in 1996. A priority integrated program of surveillance and control adjusted to the present socioeconomic conditions of the country is still going on.

Antitubercular Agents↗