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Chlamydia trachomatis infections in the United States. What are they costing us?

Chlamydia trachomatis has emerged as the most common sexually transmitted bacterial pathogen in the United States and is now recognized to cause substantial morbidity. To determine the economic consequences of chlamydial infections in the United States, we analyzed data from local, state, and national sources. We estimate that C trachomatis infections cost Americans over $1.4 billion per year in direct and indirect costs. Chlamydial infections in women account for 79% of this cost, although men and infants are also affected. Three fourths of the total cost is due to sequelae of untreated, uncomplicated infections. If the current rate of chlamydial infection persists, the projected annual costs will exceed $2.18 billion by 1990. Reducing the incidence of personal suffering and heavy economic burden imposed by C trachomatis infections requires establishment and maintenance of effective prevention/control programs.

Chlamydia Infections↗

[Genital Chlamydia infections].

Chlamydia trachomatis represents an important infectious agent for sexually transmitted diseases. In the USA more than 3 million new cases are recorded per year. The clinical picture and late complications are similar to those of gonorrhea; however, infections from C. trachomatis have relatively mild symptoms. This group of diseases may therefore be overlooked, and complications and late sequelae due to C. trachomatis thus occur more frequently in comparison to N. gonorrhoeae. From the viewpoint of general health in a population, chlamydial infections seem to be more important than the classic venereal diseases. The number of infections may be underestimated as infected individuals may be asymptomatic and are therefore not diagnosed and the disease recorded. Knowledge about chlamydial infections has increased significantly, and C. trachomatis today can easily be diagnosed by routine laboratory methods; this report deals with current knowledge regarding the epidemiology, clinical symptoms, complications, diagnosis, and treatment of genital chlamydial infections.

Anti-Bacterial Agents↗

Diagnosis and treatment of chlamydial infections.

The major chlamydial infections are conjunctivitis and pneumonia in infants and urethritis, cervicitis, salpingitis and ocular infection in adults. Tetracyclines are usually the drugs of choice for the treatment of chlamydial infections. Erythromycin therapy is preferred for pregnant women and for neonates with conjunctivitis. Follow-up examination and treatment of sexual partners are required for the control of chlamydial infections.

Adult↗

[Genital chlamydial infections].

Chlamydia trachomatis is today the most frequent cause of sexually transmitted diseases. In spite of their usually mild, sometimes even asymptomatic course, urogenital infections with Chlamydia trachomatis can lead to severe complications (infertility, adnexitis) if not treated properly. Clinical features, complications, diagnosis and therapy are discussed in detail.

Anti-Bacterial Agents↗

Chlamydial infections. Microbiological, clinical and diagnostic aspects.

The agent of trachoma, originally regarded as a virus, was described by Halberstadter and von Prowacek in 1907. Since then, studies on Chlamydiae have shown that they are procaryocytic organisms that infect eucaryocytic cells as obligate intracellular parasites. Infections caused by these pathogenic agents occur in a wide range of avian and mammalian species. Chlamydiae are also responsible for several diseases in man, and there is a rapidly growing awareness of their public health significance. The aims of this review are to describe the microbiology and laboratory diagnosis of Chlamydiae and to reflect the clinical spectrum of human chlamydial diseases.

Animals↗

[Chlamydia infections].

Chlamydia trachomatis represents one of the most common causative agents of sexually transmitted diseases. Clinically, genital chlamydial infections are similar to gonorrhoea. Although the clinical symptoms in chlamydial infections are usually milder than those in gonorrhoea, late complications are more common and more dangerous, because the carriers may easily escape notice. The knowledge of chlamydial infections has increased during the last few years. The present report deals with recent developments in this field.

Bacteriological Techniques↗