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Forearm bone density and grip strength in women after menopause, with and without estrogen replacement therapy.

Peaking in young adulthood, both bone mass and muscle strength decrease with ageing, but bone loss may accelerate after the menopause and can be delayed by estrogen replacement therapy (ERT). This study was designed to evaluate whether, like bone density, the muscle strength was affected by the onset of menopause and/or ERT. First grip strength (GS) of young female adults (group III; n = 18; age (+/- S.E.M.) 21.8 +/- 0.4 years) was compared to that of postmenopausal women, who were divided into two groups. Group I (n = 22; age 59.6 +/- 1.6 years) was 12.5 +/- 1.7 years after the menopause and received no ERT, and group II (n = 21; age 59.5 +/- 1.1 years) was 8.3 +/- 1.2 years after the menopause and had received ERT for 3.9 +/- 2.3 years at the time of the study. GS of the postmenopausal women was significantly (P < 0.005) lower than that of the young female adults. GS did not differ significantly between both postmenopausal groups. Further analysis revealed a weak negative correlation of years since menopause with forearm bone density (r = -0.37, P < or = 0.023 for group II and III together), but not with GS. It is concluded that the later onset of menopause and estrogen replacement therapy do not seem to have a noticeable influence on muscle strength.

Adult↗

Arthroscopic reduction versus fluoroscopic reduction in the management of intra-articular distal radius fractures.

PURPOSE: Although arthroscopy offers an unparalleled view of intra-articular pathology, its use in the treatment of intra-articular distal radius fractures remains controversial. This study was designed to compare functional and radiologic outcomes of arthroscopically assisted (AA) versus fluoroscopically assisted (FA) reduction and external fixation of distal radius fractures. TYPE OF STUDY: Retrospective, case-matched comparison of 2 different procedures. METHODS: Between January 1995 and December 1999, 15 patients with comminuted intra-articular distal radius fractures underwent AA external fixation and percutaneous pinning. Fifteen patients underwent external fixation and FA reduction and pinning. Patients in both groups were matched for fracture pattern and age. RESULTS: Follow-up evaluation consisted of an evaluation of grip strength and range of motion as well as radiographic evaluation of palmar tilt, radial shortening, stepoff, and degenerative changes. Health-related quality of life outcomes were assessed using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. Patients who underwent AA surgery had significantly improved supination compared with those who underwent FA surgery (88 degrees v 73 degrees; P =.02). AA reduction also resulted in improved wrist extension (mean, 77 degrees v 69 degrees; P =.01) and wrist flexion (mean, 78 degrees v 59 degrees; P =.02). Radial shortening, Knirk and Jupiter congruity grades, and DASH scores were similar for both groups. CONCLUSIONS: AA reduction and fixation of intra-articular distal radius fractures permits a more thorough inspection of the ulnar-sided components of the injury. At follow-up evaluation, patients who underwent AA procedures had a greater degree of supination, flexion, and extension than patients undergoing FA surgery. LEVEL OF EVIDENCE: Level II prospective cohort study.

Adult↗

The effect of physical training on workload, upper leg muscle function and muscle areas in patients with chronic heart failure.

OBJECTIVE: To investigate the effect of physical training (PTr) on upper leg muscle area, muscle strength and muscle endurance expressed as upper leg muscle function (ULMF) in relation to exercise performance in CHF. DESIGN: Randomised to a training (TG) or control group (CG). SETTING: Outpatient cardiac rehabilitation centre of community hospital. PATIENTS: 77 CHF patients (59 men and 18 women), NYHA class II/III, age 59.8+/-9.3 years, LVEF 27+/-8%. Sixteen patients dropped out during the intervention period, 61 patients (M/F:46/15) completed the study. INTERVENTION: PTr (combined strength and endurance exercises) four times per week, twice supervised and twice at home, during 26 weeks. MAIN OUTCOME MEASURES: LVEF, body composition, daily physical activity, exercise performance, upper leg muscle area and isokinetic leg muscle variables. RESULTS: Workload and peak oxygen consumption decreased in the CG (-4.1% and -4%) but increased in the TG (+5% and +4%) following PTr (p<0.05, ANOVA repeated measures). Hamstrings area decreased in the CG and did not change in the TG (p<0.05, ANOVA repeated measures). ULMF improved in the TG, but remained unchanged in the CG (+13.0% and 0.0, respectively, p<0.05; ANOVA repeated measures). At baseline and after intervention nearly 60% of the variance in maximal workload was explained by ULMF and quadriceps muscle area (multiple regression analysis). CONCLUSIONS: In CHF patients, home-based training in conjunction with a supervised strength and endurance training program is safe, feasible and effective and does not require complex training equipment. Physical training prevented loss of hamstrings muscle mass and improved exercise performance by enhancing muscle strength and endurance.

Exercise↗

Ligament reconstruction with trapezium retention arthroplasty for carpometacarpal arthritis.

PURPOSE: The purpose of this study is to provide a qualitative and quantitative assessment of results in a consecutive series of patients with carpometacarpal arthritis using a trapezium-retaining interposition arthroplasty. METHODS: Between 1999 and 2002, 16 patients with basal joint arthritis were treated with a trapezium-retaining interposition arthroplasty. Fourteen of these patients were evaluated at a mean follow-up time of 20 months (minimum, 12 months) and were compared based on clinical outcome, presurgical and postsurgical x-ray evaluation, and range of motion, grip-strength, and pinch-strength values. RESULTS: Average trapezial height values as quantified by the trapezial space to proximal phalanx ratio were very similar before and after surgery. Average grip-strength values improved significantly. Although average pinch-strength and average range of motion values improved neither of these comparison values were significant. Thirteen of the 14 patients (93%) were satisfied with their results as quantified by postsurgical Disabilities of the Arm, Shoulder, and Hand questionnaires. CONCLUSIONS: Ligament reconstruction with trapezium retention arthroplasty of the basal joint not only successfully maintains trapezial height but also yields patient satisfaction rates comparable to those achieved with other forms of basal joint arthroplasty.

Adult↗

Reflex sympathetic dystrophy: treatment with long-acting intramuscular corticosteroids.

In an 8-year period, 69 patients with reflex sympathetic dystrophy, who were followed at least 1 year, were treated with active exercises and injections of long-acting methylprednisolone. Of these, 22 patients did not respond to this treatment and 47 patients obtained significant improvement. All 47 were relieved of night and rest pain. Proximal interphalangeal motion improved from an average of 39 degrees to an average of 75 degrees. Grip strength was an average of 7 lb. before treatment and 29 lb. after treatment.

Anti-Inflammatory Agents↗

[Change in muscle strength in patients with anorexia nervosa during inpatient treatment--a pilot study].

OBJECTIVE: Changes in muscular strength during treatment of inpatients suffering from anorexia nervosa were to be documented by exact measurement. METHODS: The maximum strength of each side of the body was measured in 10 patients in the 1st, 2nd, 3rd, 4th, 6th, 8th and 10th weeks of inpatient treatment by means of a series of four different exercises. A well-established measurement technique, including the computer program "Quantitative Muscle Assessment", was used. All patients showed comparable symptoms of an anorexia nervosa, restricting type before admission (pure food restriction without over-exercising). RESULTS: A polyphase course of the restitution of muscular strength could be seen in all patients. Since it is easily applied, the exercise "handigrip" has been used frequently elsewhere. In our study it failed to show a consistent development, in contrast to other muscle groups studied. Differences between the left and right sides could not be observed. CONCLUSIONS: Patients with anorexia nervosa showed an objectively comparable inter-individual polyphase increase in the maximum strength of the muscles under investigation during weight restitution.

Adolescent↗

Long term outcome of early active mobilization following flexor tendon repair in zone 2.

We reviewed 34 patients with 65 zone 2 flexor tendon injuries in 39 digits whose outcome had been prospectively studied in an earlier investigation at a mean of 10.6 years after repair. Grip strength was assessed using a Jamar dynamometer. Outcome of grip strength in relation to normal data indicated an excellent or good outcome in 94% of patients, fair in 3% and poor in 3%. Using the grading system recommended by the American Society for Surgery of the Hand, the active range of motion was graded as excellent or good in 75% of digits, fair in 15% and poor in 10%. These results compare favourably with those of the original study with 5/39 of digits showing an improvement from good to excellent. Sixteen of the 34 of patients continued to suffer from cold sensitivity.

Adolescent↗

Modulation of arterial baroreflex control of muscle sympathetic nerve activity by muscle metaboreflex in humans.

We aimed to investigate the interaction [with respect to the regulation of muscle sympathetic nerve activity (MSNA) and blood pressure] between the arterial baroreflex and muscle metaboreflex in humans. In 10 healthy subjects who performed a 1-min sustained handgrip exercise at 50% maximal voluntary contraction followed by forearm occlusion, arterial baroreflex control of MSNA (burst incidence and strength and total activity) was evaluated by analyzing the relationship between beat-by-beat spontaneous variations in diastolic arterial blood pressure (DAP) and MSNA both during supine rest (control) and during postexercise muscle ischemia (PEMI). During PEMI (vs. control), 1) the linear relationship between burst incidence and DAP was shifted rightward with no alteration in sensitivity, 2) the linear relationship between burst strength and DAP was shifted rightward and upward with no change in sensitivity, and 3) the linear relationship between total activity and DAP was shifted to a higher blood pressure and its sensitivity was increased. The modification of the control of total activity that occurs in PEMI could be a consequence of alterations in the baroreflex control of both MSNA burst incidence and burst strength. These results suggest that the arterial baroreflex and muscle metaboreflex interact to control both the occurrence and strength of MSNA bursts.

Adult↗

Heritability of maximal isometric muscle strength in older female twins.

The purpose of the present study was to examine genetic and environmental effects on maximal isometric handgrip, knee extension, and ankle plantar flexion strength. In addition, we wanted to investigate whether the strength of these three muscle groups shares a genetic component or whether the genetic effect is specific for each muscle group. Muscle strength was measured as part of the Finnish Twin Study on Aging in 97 monozygotic (MZ) and 102 dizygotic (DZ) female twin pairs, aged 63-76 yr. The MZ and DZ individuals did not differ from each other in age, body height, weight, or self-related health. The age-adjusted pairwise (intraclass) correlations of the MZ and DZ twins were, respectively, 0.462 and 0.242 in knee extension, 0.435 and 0.345 in handgrip, and 0.512 and 0.435 in ankle plantar flexion strength. The multivariate genetic analysis showed that handgrip and knee extension strength shared a genetic component, which accounted for 14% (95% confidence interval: 4-28%) of the variance in handgrip strength and 31% (95% confidence interval: 18-45%) in knee extension strength. The influence of genetic effects on ankle plantar flexion strength was minor and not significant. Furthermore, these three muscle groups had a nongenetic familial effect in common and nonshared environmental effects in common. The results suggested that muscle strength is under a genetic regulation, but also environmental effects have a significant role in explaining the variability in the muscle strength.

Aged↗

Reliability and validity of pinch and thumb strength measurements in de Quervain's disease.

The purpose of this study is to evaluate the test-retest reliability and construct validity of pinch and thumb strength measurements in subjects with de Quervain's disease. Maximal palmar pinch and thumb strength (adduction, extension, abduction, and flexion) were measured using, respectively, a pinch gauge and a biaxial dynamometer. The reliability was estimated using the generalizability theory. The validity hypotheses were as follows: 1) the pinch and thumb strength of the symptomatic side would be significantly lower than that of the asymptomatic side, and 2) the strength loss would be greater for thumb extension and abduction. The reliability was high for all strength measurements, pinch strength being the more reliable one. The pinch and thumb strength in all directions evaluated was significantly decreased on the symptomatic side (p<0.003); no direction showed a greater decrease than the others. The results suggest that pinch and thumb strength measurements are reliable and able to show a decreased strength on the symptomatic side in this population.

Adult↗

Effect of regular use of high-dose nebulized beta2-agonists on resting energy expenditure, weight, and handgrip strength in patients with chronic airflow limitation.

STUDY OBJECTIVES: A proportion of patients with chronic airflow limitation (CAL) have a raised resting energy expenditure (REE). The mechanism underlying this is not known. The question of whether the increased REE seen in some patients with CAL is due to beta2-agonist therapy has arisen, and the aim of this study was to examine REE, body composition, and peripheral muscle strength in patients before and after the use of regular high-dose beta2-agonists administered by nebulizer. DESIGN: Prospective observational study. SETTING: Respiratory outpatient clinic. PARTICIPANTS: Twenty outpatients with CAL being considered for a home nebulizer prescription. INTERVENTIONS: REE was measured by indirect calorimetry. Fat-free mass and handgrip strength were measured. Quality of life was assessed by the St. George's Hospital Respiratory Questionnaire. All subjects were assessed independently of this study for provision of a home nebulizer using a standard protocol. Based on the assessment, either standard-dose salbutamol therapy was continued or a nebulizer was provided with a prescription for high-dose salbutamol (5 mg qd). A mean of 8.1 months later (range, 3 to 16 months), 16 patients were restudied. MEASUREMENTS AND RESULTS: Eight patients had been taking regular high-dose nebulized salbutamol, and eight had continued taking standard-dose salbutamol by metered dose inhaler. There was no difference in baseline measures between the group who were later prescribed high-dose salbutamol and the group who were not. There were no changes in REE, anthropometric measures, or handgrip strength over time in either of the groups. CONCLUSIONS: The long-term use of high-dose nebulized beta2-agonists in patients with chronic airflow limitation has no effect on baseline REE, handgrip strength, weight, or body composition.

Administration, Inhalation↗

Scaphoid fractures: dorsal versus volar approach.

Twenty-six patients with scaphoid fractures were treated with internal fixation using a cannulated differential pitch compression screw. Sixteen patients underwent a dorsal approach (group 1) 10 patients a volar approach (group 2). Average time from injury to surgery was 6.6 months (range: 0.3-19 months) for group 1 and 8.3 months (range: 0.3-24 months) for group 2. The rate of union, determined by radiographs and clinical examination, was 81% in group 1 and 80% in group 2. No significant differences were noted between the groups for dorsiflexion/palmar flexion, radial deviation, grip strength, and pain level.

Adolescent↗

Impact of a daily 10-minute strength and flexibility program in a manufacturing plant.

In summary, employees' flexibility and mood showed modest improvements following the implementation of a plant-wide, 10-minute, daily flexibility and strength program. The initial six-week pilot study, administered prior to the plant-wide program implementation, successfully assessed program feasibility, assessed the efficiency of program implementation, identified administrative and logistical concerns, and generated pilot data needed to secure managerial support. Despite the noted significant increases in grip strength in the pilot study, no increases were observed following the six months of plant-wide implementation. This may be related to the differences in low average pretest grip strength for the pilot study compared to the higher scores for the main study population. The pilot study subjects may have received a sufficient exercise stimulus to increase grip strength over the course of six weeks. In contrast, this may not have been the case for the main study subjects due to their higher initial mean grip strength. An increased number of exercises designed to directly impact grip strength may be needed to improve this parameter.

Biomechanical Phenomena↗

Using the BTE Primus to measure grip and wrist flexion strength in physically active wheelchair users: an exploratory study.

OBJECTIVE: The purpose of this study was to establish test-retest reliability values for the newly designed grip and wrist attachments of the BTE Primus and to determine criterion-related validity of the new grip attachment against the Jamar dynamometer. An additional purpose was to explore the differences in grip and wrist flexion strength between wheelchair users and control participants without disabilities and to examine the effect of body position on strength in persons without disabilities. METHOD: Wheelchair users and matched controls (13 per group) were tested for grip and wrist flexion strength on the BTE Primus and for grip on the Jamar dynamometer. RESULTS: The BTE Primus grip attachment was found to be valid and reliable. No significant differences were found in static and dynamic grip or wrist flexion strength between the two groups or in the sitting versus standing position for the control group. CONCLUSION: The findings suggest that the BTE Primus may be used to assess grip and wrist flexion strength validly and reliably for both wheelchair users and persons without disabilities.

Adolescent↗

Anthropometric, psychomotor, and hemodynamic changes during twenty-one continuous days of eating only meals, ready-to-eat (MREs).

This study investigated anthropometric, psychomotor, and hemodynamic changes in young adult men during 21 continuous days of eating only meals, ready-to-eat (MREs). The MRE diet group lost more weight and bodyfat (significant at abdominal site, total skinfolds, and total bodyfat percent), and had significantly greater gains in hand grip strength than did controls. Results support the contention that, when eaten as designed, MREs are nutritionally adequate for maintaining body weight and muscle strength without adverse effects.

Adult↗

Effects of athletic strength and endurance exercise training in young humans on plasma endothelin-1 concentration and arterial distensibility.

Strength exercise training induces a decrease in arterial distensibility, whereas endurance exercise training causes an increase in arterial distensibility. Endothelin-1 (ET-1), which is produced by vascular endothelial cells, has potent vasoconstrictor and proliferative activity on vascular smooth muscle cells. We hypothesized that endogenous ET-1 participates in alteration of arterial distensibility by different exercise training types (i.e., strength and endurance exercise training). The purpose of the present study was to investigate plasma ET-1 concentration and arterial distensibility in strength- and endurance-trained athletes. Subjects were male strength-trained athletes (discus, hammer, or javelin throwers; 22.2 years; SA), male endurance-trained athletes (long- or middle-distance runners; 20.7 years; EA), and sedentary healthy men (20.6 years; sedentary control, SC). Maximum hand-grip strength was markedly greater in SA compared with EA and SC (55.3 vs. 41.1 vs. 40.5 kg, P < 0.05). Maximum oxygen uptake was markedly greater in EA than in SA and SC (60.9 vs. 43.1 vs. 43.6 ml/kg/min, P < 0.05). Arterial pulse wave velocity (PWV), which is an index of arterial distensibility, was significantly higher in SA than in EA and SC (688 vs. 529 vs. 601 cm/sec, P < 0.05). In EA, PWV was significantly lower in comparison to that in SC (P < 0.05). Thus arterial distensibility was lower in SA than in EA and SC and higher in EA than in SC. Plasma ET-1 concentration was significantly higher in SA compared with EA and SC (1.64 vs. 1.12 vs. 1.24 pg/ml, P < 0.05). Plasma ET-1 concentration tended to be lower in EA than in SC. These results suggest that the difference in plasma ET-1 level may participate in the mechanism underlying different adaptation of arterial distensibility between strength- and endurance-trained athletes.

Adult↗

[Durability of bonding between 4-META/MMA-TBB resin to dentin pretreated with 10-3. The effect of 10-3 pretreating period and subsequent glutaraldehyde treatment].

Adhesion durability between dentin pretreated with 10-3 and 4-META/MMA-TBB resin was studied. Reduction of etching periods with 10-3 was not so effective as expected. The weakening of bond strength during immersion in water at 37 degrees C to the dentin pretreated for 1 sec occurred faster than those for either 5 sec or 10 sec. The strength decreased from 12 MPa at 1 day to 9 MPa at 3 months, 3 MPa at 6 months and finally 2 MPa at 1 year in the case of 1 sec pretreated dentin. On the other hand, the strength became half after the storage in water for 1 year in the cases of 5 and 10 sec pretreated dentins. Combination of 10-3 pretreatment and subsequent glutaraldehyde treatment could stabilize the decrease but not completely. SEM and TEM examinations suggested that dentinal collagen exposed by the etching but not entangled and impregnated by poly (4-META-co-MMA) easily deteriorated by water during the longer immersion. Collagen modified with 10-3 and then with glutaraldehyde was also changed by the longer immersion.

Acid Etching, Dental↗

Modified arthroplasty of the distal radio-ulnar joint.

We report a modified arthroplasty technique for limited degenerative arthritis of the distal radio-ulnar joint, in which the proximal hyperemic portion of the joint is resected with preservation of the unaffected distal portion. The charts of ten patients, one bilateral, were retrospectively reviewed and all 11 wrists were examined after an average of 30 months. All patients reported decreased pain and increased joint function. Grip strength, supination and pronation were comparable to the opposite, unaffected side.

Adult↗