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A case of monomorphic adenoma, canalicular variant, has been presented. This lesion is a rare benign neoplasm most often found in the minor salivary glands of the upper lip. This appears to be the first reported case of the lesion in a non-Caucasian.
Eight patients with multiple oral dysplastic epithelial lesions were followed by clinical examinations and serial biopsies for periods varying from four to 22 years. The dysplasias and in situ carcinomas were characterized by persistence, recurrence, and eventual progression to invasive squamous cell carcinoma. It could not be determined whether dysplasia and in situ carcinoma were separate clinical-pathologic entities with similar end points or whether they were part of a continuum in a spectrum of epithelial neoplasia. The need for close clinical observation and local excision was emphasized because of the multiplicity of lesions and because of the protracted clinical course. Treatment of these patients was problematic because of similarities of the disease to lichen planus. It is possible that they had a premalignant disease process that mimicked lichen planus, or that they had an unusual form of lichen planus for which criteria have not been established. The progressive nature of the disease was exemplified by one death, one patient with cervical metastasis, and one with generalized remote metastatic disease.
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This article reviews our experience with the use of the cancer atlas of Slovakia, published in 1989 which presented simultaneously the cancer incidence and mortality rates derived from national population-based cancer registries. Contrary to all expectations, the role of the environmental pollution was confirmed only for nonmelanoma skin cancer and arsenic exposure. Valuable information was obtained also for the study of dynamics of cancer distribution, which revealed a shift in the incidence of stomach cancer to the east and its replacement with colorectal cancer in the western part of the country. Of enormous importance for the comprehensive cancer care and control is the knowledge of incidence and mortality rates at the level of individual districts.
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In summary, the use of free tissue transfers for nasal reconstruction offers a wide variety of tissues that provide cutaneous coverage, underlying support, and nasal lining. Obtaining the final aesthetic result frequently requires defatting and other touch-up procedures, which usually can be done under local anesthesia on an outpatient basis.
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A biologic classification based on clinical behavior and endothelial cell characteristics is used to divide vascular birthmarks into two groups: hemangiomas and vascular malformations. This system is applied to vascular anomalies of the maxillofacial region and is demonstrated with illustrative cases. The distinction between hemangioma and vascular malformation is important for maxillofacial surgeons because hemangiomas rarely affect bone, whereas malformations affect bone in 35% of cases.
After a short comment on the essential data concerning the pathology, clinical aspects and treatment of orofacial haemangiomas, the author presents his own method of treatment by intratumoral ligation. He describes the technical details by which interception of the blood supply to the haemangioma is achieved and also breakdown of the angiomatous mass into segments by the occlusion of vascular channels, thus completely interrupting the intratumoral blood flow. Obstruction of vascular lumina, endothelial atrophy, blood clot organization in the small diverticula between them and also subsequent fibrous hyperplasia which take the place of the vascular hyperplasia ensue. The method was used in 31 cases of cavernous haemangioma in different sites; the results, with follow-up periods of 1-8 years prove its efficacy.
The flash lamp-excited dye laser is ideal for treating benign superficial vascular cutaneous lesions. Port-wine stains, telangiectases, spider angiomas, or hemangiomas may be treated without pain. If used properly, complications such as skin texture changes, hypopigmentation, and scarring are extremely rare. The flash lamp-excited dye laser works on the principle of selective photothermolysis, which allows selective damage to the target vessel without affecting surrounding tissue. Lesions like xanthelasma palpebrarum, keloid scars, and warts may also be treated by the flash lamp-excited dye laser. This study presents the results of treatment with this laser in our patients.
Ten female infants were referred for symptomatic hemangiomas in the anogenital area. (One had had steroid treatment prior to consultation.) The natural history of these lesions is well known. Virtually all will spontaneously involute over a period of years. However, the lesions reported were particularly troublesome because of repeated ulcerations and subsequent pain. Prior treatment had been local wound care with antibiotic ointment and Telfa-type dressings. After referral from a family practitioner or pediatrician, argon laser treatment was performed in an outpatient setting. Eight of the 10 patients were treated with local anesthesia, and 2 had general anesthesia. All lesions healed in 1 to 5 weeks. No patients referred during this period were excluded from this series. All who received treatment were included. All the lesions involuted following treatment. In our estimation, the final result is identical to what may be expected after spontaneous involution of an ulcerated or infected hemangioma. The major difference is that involution occurred in a few weeks in laser-treated patients rather than a period of months or years. Ulcerated hemangiomas of the anogenital area have significant morbidity that can be efficiently avoided with the use of argon laser therapy. Lesions of the anogenital area have a strong predilection for females.