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[Vesico-renal reflux caused by neurogenic bladder from spina bifida in childhood].

The authors report their experience related to 35 cases of neuropathic bladder examined during the last 12 months. They discuss the method followed for the study of each patient. Particularly they underline the importance of: scintiscan in the valuation of the renal function and urodynamic tests for a better knowledge of vesical disfunction. In the patient with vesicorenal reflux they propose two kinds of treatment (medical or surgical), selected after a complete valuation of radiologic, functional and urodynamic tests. They underline the importance of the pharmacological treatment, single or associated with surgical operation, in the patients with reflux and with a low vesical compliance and/or hyperreflexic bladder. Finally the Authors discuss the antireflux surgical techniques that they prefer and that have consented them to obtain excellent results.

Adolescent↗

[Percutaneous direct current treatment (myelotron) of neurogenic bladder disorders due to injuries of the lower motor neurons].

We examined 18 patients with lesion of the lower motor neuron, conditioned partly by lesion of the spinal cord, partly by lesion of the peripheral vesical nerves, before and after the percutaneous electrostimulation (myelotron) and established the urodynamically verified effect. Apart from one case of unclarified and fully therapy-resistent atony of the urinary bladder we found in all patients a subjective improvement of their complaints (retarded beginning of miction, spontaneous miction only with straining, large quantities of residual urine). Objectively an improvement of the sensitivity of the urinary bladder or of the motoricity appeared, in most cases both. We could not establish an essential influence on the tonus of an empty bladder and the tonus of the sphincter musculature. In all patients the residual urine could be reduced drastically, after the treatment the major part of the patient could urinate without residual urine.

Adult↗

[Long term results of electric stimulation of the conus medullaris in a case of neurogenic bladder].

The authors present long term results (19 to 45 months: Average 37 months) of electrical stimulation of the conus medullaris in neurologic bladder. In 3 cases, the result remain excellent: efficient stimulation, normal micturition, absence of residual urine. In 6 cases, after a long period of normal function, the micturition is poor with residual urine, eventhough the conus medullaris stimulation always produces a satisfactory contraction of the detrusor. In four cases the relapse is due to disease of the external sphincter region, poorly or untreated. In female patients the results are better than in male patients, with positive results in 2 of the 3 women and 1 of the 6 men. The authors find that their results can be compared with those of B. NASCHOLD, originator of the method. They emphasize the necessity of a close collaboration with the urologist to maintain excellent results.

Adolescent↗

Studies of the neurogenic bladder.

A series of 36 patients with specific neurological lesions affecting those parts of the nervous system thought to be involved in the control of bladder function have been studied by urodynamic, electromyographic and neurohistochemical means and the results compared with those obtained in 20 control subjects. In patients with pelvic nerve injury urethral sphincter electromyography (EMG) revealed abnormal motor units and the density of bladder innervation was significantly reduced (P less than 0.01). By contrast, in patients with distal autonomic neuropathy the innervation of the striated muscle of the urethra was unaffected and although there was an almost total loss of nerves from the bladder muscularis, the subepithelial plexus of nerves was preserved. In patients with progressive autonomic failure and multiple system atrophy, the bladder neck was incompetent in every case and the striated muscle of the urethra was affected by a process of denervation and re-innervation. These findings serve to distinguish patients with autonomic failure from those with idiopathic Parkinson's disease and influence the selection of patients for transurethral surgery.

Autonomic Nervous System Diseases↗

[A case of neurogenic bladder caused by spinal cord traction in childhood. Diagnostic and therapeutic aspects].

The diagnostic and therapeutic aspects of a pediatric case of tethered cord syndrome are described. The urological symptoms were of primary importance; bladder dysfunction was confirmed urodynamically; voiding cystourethrography showed trabeculation and elongation of bladder with distal sphincter obstruction and left vesicoureteral reflux. The bladder dysfunction was managed satisfactorily with pharmacological therapy and clean intermittent self-catheterization. Nuclear magnetic resonance demonstrated a tethered spinal cord with lipoma of cauda equina. The importance of neuroradiology is emphasized in order to establish an early and precise diagnosis. Early neurosurgery is justified by the need to avoid any progressive and severe lower extremity deficit and by the high frequency of urological improvement in cases treated with spinal operation. However, in this case, clinical and pathological findings suggested to defer any surgical intervention.

Child↗

[A case of neurogenic bladder complicated by an acute rash syndrome (measles?)].

A 24-year-old female patient was was admitted because of urinary retention, four days after the development of rash with fever to be diagnosed as measles by a doctor. Neurological examinations showed hyperesthesia in lower thoracic regions and increased deep tendon reflexes in lower extremities. Cystometric findings revealed an areflexic bladder with normal sensation. Cerebrospinal fluid examination showed mononuclear pleocytosis and slightly elevated levels of protein. There was no significant increase in serum measles antibody titer. She regained normal voiding by conservative treatment with an indwelling catheter for four days. The bladder motor paralysis was probably due to non-transverse myelitis in sacral spinal region. Neurological complications of measles are briefly discussed.

Adult↗