[The influence of roentgen irradiation on the course of acute Salmonella infection (Experimental study)].
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The effect of Eimeria tenella infection on the Salmonella enteritidis infection in chickens was investigated in three experiments. Each experiment consisted of an uninfected control, birds infected with E. tenella, birds infected with S. enteritidis, and birds infected with a combination of E. tenella and S. enteritidis. A dose of 2 x 10(4) sporulated oocysts of E. tenella was given to each chicken. In Experiment 1, each chicken was infected with 10(5) cfu/d of S. enteritidis for 3 consecutive d starting 1 d after coccidia exposure and necropsied 4, 7, 10, and 14 d after coccidial infection. In Experiments 2 and 3, each bird was infected with 10(2) cfu/d and 10(1) cfu/d of S. enteritidis respectively, for 2 d beginning 4 d after coccidia exposure, and were killed 7, 10, and 14 d postinfection with E. tenella. Results showed that interaction between S. enteritidis and E. tenella was significant in Experiments 1 and 2, but not in Experiment 3, manifesting that the cecal Salmonella population were significantly increased by coccidial infection in birds killed 4, 10, or 14 d after coccidia exposure in Experiment 1 and in birds killed 14 d after coccidial infection in Experiment 2. The dose size of S. enteritidis was an important factor for the synergistic relationship between S. enteritidis and E. tenella. Frequency of recovery of S. enteritidis in liver and spleen was not increased by E. tenella infection.
The case history of a 75 year old man is demonstrated, who developed an abscess in the scar after B-II-resection 30 years ago. In this abscess S. typhi murium was detected. Diabetes mellitus was an additional risk factor. A review of the literature is given concerning extraintestinal manifestations of salmonellosis with emphasis to the predisposing conditions.
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A 65-year-old man with salmonella bacteraemia developed a retroperitoneal collection as a result of infection and subsequent rupture of the abdominal aorta. Computed tomography (CT) showed the collection but there was no aneurysm on CT or at surgery. The main diagnostic feature of salmonella aortitis is the presence of an aneurysm; this report indicates that a non-aneurysmal infected aorta can rupture. The importance of considering a ruptured aorta as the cause of retroperitoneal collections is emphasised, even when the aorta is of normal calibre.
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Studied is the active immunoprophylaxis of calves on farms with a Salmonella dublin infection, using a live vaccine produced with a S. dublin attenuated strain. The disease was fully suppressed among calves through vaccination after the tenth day following birth. However, the source of infection was not done away with, and it was most likely to be found in adult cattle. This was reasonable to believe as there was a second outbreak of the disease in a group of unvaccinated, newborn calves. The regular vaccination is suggested of all newborn calves up to the time when the adult population would occasionally be replaced.
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