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Selective sclerotherapy of the internal spermatic vein in patients with varicoceles.

Percutaneous occlusion therapy of insufficient internal spermatic veins was performed successfully as an outpatient procedure in 155 patients with varicoceles. The administration of the sclerosing agent (Varicocid) through a catheter selectively introduced into the spermatic vein caused therapeutic occlusion. Follow-up studies, both clinical and phlebographic, confirmed the effectiveness of the treatment.

Follow-Up Studies↗

Long-term results after sclerotherapy of the spermatic vein in patients with varicocele.

Ninety-seven patients received transfemoral sclerotherapy of the spermatic vein for varicocele. After observation for 2 to 5 years, follow-up was available in 69 patients (71.2%), in 11 of whom the procedure failed (16.0%). Complications during angiography (N = 12, 12.4%) or sclerotherapy (N = 31, 32.0%) did not require hospital treatment. At least one parameter of the spermiogram was improved in 25 of 32 patients (78.1%). Forty-four of 69 patients (63.8%) treated because of a childless marriage, and whose wives were not known to be infertile, had a pregnancy rate of 47.7%. Thi method may be considered equal to surgical procedures in achieving venous occlusion; furthermore it is simple and can be used on an outpatient basis without anesthesia.

Adult↗

Recurrent stomal variceal bleeding. Successful treatment using injection sclerotherapy.

Stomal varices may develop in patients with gastrointestinal stomas and portal hypertension. Bleeding often is recurrent and may be fetal. A 48-year-old woman had six major stomal variceal bleeds requiring 20 U of blood in the four months before beginning stomal sclerotherapy. "Paravariceal" injections using various combinations of sodium tetradecyl sulfate, ethanol, and saline resulted in a decrease in blood transfusions to 3 U during a 20-month follow-up. Injection sclerotherapy deserves consideration in patients with recurrent stomal variceal bleeding.

Female↗

Sclerotherapy for massive enterostomy bleeding resulting from portal hypertension.

Three patients with frequent and massive hemorrhage from enterostomy (colostomy 2, ileostomy 1) due to portal hypertension are reported. The hemorrhages were treated with sclerotherapy by submucous injections of polidocanol (Ethoxysclerol) or phenol (5 percent) almond oil. In one patient, a complete and long-term stoppage of the bleeding was achieved. In the second patient, a marked reduction in the amount of blood loss and an increase in the time between bleeding episodes occurred. In the third patient, only a short-lived effect of a few weeks was reached.

Aged↗

A randomized trial of photocoagulation or injection sclerotherapy for the treatment of first- and second-degree hemorrhoids.

One hundred thirty-five patients with a diagnosis of hemorrhoids were randomized to receive either photocoagulation (P) (N = 73) or injection sclerotherapy with phenol (I) (N = 62). Each patient was assessed at one, four, and 12-month intervals after treatment. At one, four, and 12 months, there was no clinical difference between the groups; at 12 months, however, the proportion of patients who were symptomatically improved or asymptomatic was 59 percent after photocoagulation compared with 50 percent of those treated by injection (P = 73 percent; I = 50 percent). Seven patients treated by photocoagulation required repeated therapy compared with only one after injection (P less than 0.02). Additional therapy was used in eight patients after photocoagulation, as compared with three after injection. The operation rate for each group, however, was similar. There were no complications of therapy. Photocoagulation is an easy, non-invasive, safe method of treatment, giving results that are comparable to treatment by injection sclerotherapy.

Adult↗

Rectal prolapse in children.

Rectal prolapse in children is an uncommon clinical entity in western countries. Treatment is generally supportive with surgery reserved for the intractable case. If operative intervention is advised, it should consist of one of several limited procedures that can be safely performed with low morbidity: anal encirclement, presacral packing, sclerosing injection, or linear rectal cauterization.

Child, Preschool↗

Retroperitoneal abscess following sclerotherapy for hemorrhoids.

A case report of a patient who underwent submucosal injection sclerotherapy for hemorrhoids is presented. Subsequent necrosis of the underlying tissues produced a rectal perforation and retroperitoneal abscess, which necessitated emergency laparotomy and defunctioning colostomy. Healing of the perforation allowed later closure of the stoma. A brief review of the known complications of this technique has been made. It would appear that necrosis and perforation with abscess formation can be added to this list.

Abscess↗

Transluminal penile venoablation for impotence: a progress report.

Based on theoretical advantages and successful pilot experiments in dogs, therapeutic transluminal penile venoablation underwent clinical trials in 13 impotent men. Catheter access to the penile venous structures was gained via (1) direct percutaneous puncture of the deep dorsal penile vein, (2) cut-down over the dorsal vein of the penis, or (3) retrograde catheterization of internal or external pudendal veins from a femoral vein. Alternatively, needle access only was gained into (4) the preprostatic plexus or the pudendal vein, (5) the superficial penile vein, or (6) the crura. Once venous access had been gained, selective venography was performed to clarify the relevant anatomy in each case. After catheterization, venoocclusion was produced by embolization with combinations of coils and Gelfoam, followed by sclerosant. Results to date indicate high feasibility of access by a variety of methods, and the safety of transluminal venoablation. Clinical efficacy to date seems only moderate. Eight of 13 patients report subjective improvement in the quality of erections after a mean follow-up period of 5.2 +/- 2.4 months. With regard to sexual activity, 2 patients are considered cured, 2 improved sufficiently for sexual intercourse, and 9 were insufficiently improved for intercourse. Of the nine failures, two were considered cures for 3 weeks, but then relapsed for unknown reasons. Two of the 4 patients that regained potency had concomittant unilateral or bilateral pudendal arterial occlusions. Technical modifications for improving results are under continuing investigation.

Adult↗

Hemorrhoidectomy--how I do it: current views in Britain.

It is clear that there is no uniform treatment for hemorrhoids in Britain. Indeed, there is often considerable debate about the merits and disadvantages of the various methods available. It would seem that a more scientific way of assessing the management of patients is needed so that the various therapeutic measures may be properly evaluated, comparing like with like. It may then be possible to tailor the treatment for each individual more accurately, in order to confer the maximum benefit.

Cryosurgery↗

Bacteremia after proctoscopy and hemorrhoidal injection sclerotherapy.

The incidence of bacteremia following proctoscopy and hemorrhoidal injection sclerotherapy was studied in 50 outpatients undergoing both procedures. Bacteremia was found in 2 per cent of the subjects after proctoscopy and in 8 per cent after sclerotherapy. None of the subjects developed symptoms of septicemia following the procedure. It is concluded that antibiotic prophylaxis should be used before sclerotherapy in patients with valvular heart disease or compromised host defense.

Adult↗

Percutaneous penile venoablation for treatment of impotence.

Percutaneous penile venoablation with sclerosing agents and coils was performed in 58 patients. Of 104 ablations attempted, 44 of 51 (86%) transpenile, and 46 of 53 (86.7%) retrograde interventions were technically successful. In 40 patients (69%) erectile function improved (intercourse was possible in 21 without additional measures). Initially improved erectile function deteriorated in 24 patients during follow-up (in an average of 6 months); in 15 of these, intercourse was still possible with injection of vasoactive drugs. In 7 patients, repeat venoablation improved erectile function again. Hot contrast medium was slightly superior to sodium morrhuate as a sclerosing agent. In successfully treated patients, the average decrease in venous leakage was 30 ml/min vs 13 ml/min in treatment failures, with considerable overlap between both groups. Only minor complications were observed. We conclude that percutaneous penile venoablation is technically feasible, and safe. Whether the procedure will have a definite role in the treatment of venogenic impotence, however, still has to be determined.

Embolization, Therapeutic↗