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Results for “Spinal Dysraphism”

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At least 649 records · Page 36Linked to original sources

PubMed2006

[Sacrococcygeal dermal sinus presented bacterial meningitis: a case report].

A rare case of sacrococcygeal dermal sinus suffering from relapsing meningitis is presented. In addition, deference of clinical figure and pathology between sacrococcygeal region and other regions are discussed. A 10 -month-old boy was suffering from relapsing meningitis. Spinal MRI was performed to find occult spinal dysraphism because he had a pit on his hip. The MRI revealed sacrococcygeal dermal sinus. He received surgical resection of dermal sinus based on this findings. Interestingly, different from other dermal sinuses, the dermal sinus runs to caudal direction, and was fused filum terminale with dermoid cyst. This interesting pathological feature of sacrococcygeal dermal sinus seems to come from developmental difference between sacrococcygeal dermal sinus and the other dermal sinuses. Only sacrococcygeal dermal sinus is related with caudal cell mass on its pathogenesis. Because filum terminale is also developed from caudal cell mass, sacrococcygeal dermal sinus seems to be related with filum terminale. Most important differential diagnosis is coccygeal pit that is found in 1 -4% of newborn baby. The clinical feature and pathology got from our case must be very helpful to distinguish sacrococcygeal dermal sinus from coccygeal pit.

Diagnosis, Differential↗

PubMed1990

[The so-called Klippel-Feil syndrome and its orthopedic incidences].

Eighteen cases presenting Klippel-Feil syndrome were reviewed. Clinical and radiological criteria were analyzed: short neck, severe restriction of motion, and low posterior hairline which make up the classical clinical triad. Radiological abnormalities of the cervical spine included: a reduction in the number of cervical vertebrae, fused vertebral blocks (16 cases), cervical spine-bifida occulta, spinal dysraphism (12 cases). Other cervical vertebral disorders have been added which complete the original description: cervico-thoracic abnormalities (12 cases), craniocervical junction abnormalities (7 cases) and also thoraco lumbar abnormalities (5 cases). Although this syndrome is essentially descriptive, orthopaedic complications may occur: scoliosis (9 cases) of which only two had an increasing deformity and required posterior spine stabilisation; cervico-occipital instabilities (2 cases) which although rare, should be sought out with care because they can have serious consequences; Sprengel's deformities (7 cases) which did not warrant operative intervention. The Klippel-Feil syndrome, Wilderwanck syndrome, and Goldenhar syndrome are all close descriptive entities, and have limited surgical consequences.

Atlanto-Occipital Joint↗

PubMed1990

[Clinical and neuroradiological features of syringomyelia associated with Chiari malformation].

The clinical presentation and radiological features were analyzed in 30 cases of syringomyelia associated with Chiari malformation. None of the patients had spinal dysraphism. The age on admission ranged from 6 to 59 years with a mean of 27 years. Syringomyelia was diagnosed by CT myelography and or MRI from 1982 to 1988. The initial symptoms were skeletal abnormality (43%) such as scoliosis (12 cases) or pes cavus (one case), unilateral pain or numbness (40%) and unilateral motor weakness (17%). Frequently seen signs on admission were sensory deficit (100%), scoliosis (57%), muscle weakness (57%), muscle atrophy (37%) and lower cranial nerve palsy (40%). The neurological findings were asymmetrical in all patients. The characteristic neurological findings in the cases presenting under 20 years of age were unilateral sensory and motor deficits (61%) with decreased or absent deep tendon reflex on the same side. The localization of the syrinx in axial section varied according to the level even in the same case. In 15 cases with unilateral sensory disturbance or unilateral sensory and motor deficit, the syrinx was located in the region corresponding to the posterolateral portion on the same side as that of sensory disturbance in the cervical or thoracic level. On the other hand, in 15 cases with bilateral sensory and motor deficit, the syrinx was located in the central portion and extended into the posterolateral portion of the more affected side.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

PubMed1990

Non-neurogenic neurogenic bladder.

A case report of a 10 year old boy, presenting with a non-neurogenic neurogenic bladder is described and taken into account to discuss the most common etiologies of voiding dysfunction in children. Focus is placed on spinal dysraphism as a cause of a neurogenic bladder in opposition to non-neurogenic neurogenic bladders, to stress the differences in etiology, pathology and treatment.

Child↗

PubMed1986

Magnetic resonance imaging in syringomyelia.

The aim of the study was to assess the reliability of magnetic resonance imaging (MRI) in the detection of syrinx cavities and to determine the proportion of cavities associated with Chiari malformation. MRI was performed in over 120 patients with neurologic deficits referable to the cranio-cervical junction. Forty-one patients were also evaluated by CT myelography (CTM). CTM demonstrated appearances consistent with intramedullary cavitation in 14 patients. MRI detected 11 of these but in 3 the appearances, including cord size, were normal. In the entire study 27 syrinx cavities were demonstrated by MRI, 8 associated with trauma, posterior fossa or spinal tumours, or spinal dysraphism. Of the remaining 19, tonsillar ectopia was present in 10 (53%). It is concluded that a lack of concordance between MRI and CTM exists in the detection of small cavities in the normal sized cord, and that syringomyelia without evidence of tonsillar ectopia is identifiable by MRI more frequently than might be anticipated.

Adolescent↗

PubMed1986

Experimental production of congenital malformation of the central nervous system in rat fetuses by single dose intragastric administration of ethylenethiourea.

Ethylenethiourea (ETU) is a degradation product from ethylenebisdithiocarbamate such as Zineb and Maneb which have been extensively used in food crops and ornamental plants. Khera (1973, 1975, 1977) reported that administration of ETU to pregnant rats could induce anomalies in the visceral organs and the central nervous system of fetuses in food toxicology. From this point, in an attempt to better understand the pathomechanism of teratogenesis in the central nervous system, we have studied the effects of ETU on the central nervous system of rat fetuses. In this study, pregnant Sprague Dawley (SD) rats were used and subjected to ETU. Various types of congenital malformations of the central nervous system are presented in rat fetuses including spinal dysraphism associated with hindbrain crowding, exencephaly, meningoencephalocele, microencephaly, hydraencephaly and hydrocephalus. Each depended on the gestation days of the ETU administration and dosages.

Abnormalities, Drug-Induced↗

PubMed1985

The computed tomographic findings in benign diseases of the vertebral column.

Computed tomography (CT) has revolutionized the diagnosis of diseases affecting the vertebral column. CT effectively demonstrates the bony vertebral column with its intervertebral articulations, its soft tissue contents, and the surrounding paravertebral soft tissues. The vertebral column may be the site of involvement of a wide variety of benign diseases. These diseases may be congenital or acquired and may arise from within the spinal canal, from the vertebrae themselves, or from the paravertebral soft tissues. These lesions may be unsuspected clinically and may be detected incidentally in patients undergoing CT of the spine for nonspecific complaints. The axial projection is extremely useful in displaying spinal anatomy and pathology and, combined with sagittal and coronal reformation, provides diagnostic information not possible from any other radiological modality. More invasive radiological procedures, such as myelography, may in many cases be obviated, especially if shorter segments of the vertebral column are to be surveyed. The CT findings in many cases are sufficiently characteristic to enable a specific diagnosis to be made.

Arthritis, Rheumatoid↗

PubMed1968