SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
This article describes two additional examples of this unusual condition; two others were reported previously. The microscopic features are those of the hyperplastic dental follicles that occur in regional odontodysplasia. However, the teeth are not defective, as in regional odontodysplasia. This rare condition is sufficiently distinctive to be considered a pathologic entity.
Two cases of severe dens invaginatus malformation of teeth are presented. In the first case apical abscess formation occurred before root end closure. In the second case the dysmorphic tooth form may be considered a possible cause of retarded eruption.
A case of trichorhinophalangeal syndrome type I (Giedion's syndrome) is presented and discussed. Pathologic alterations, including oral and facial manifestations, and the clinical history of this unusual condition are described. The case is compared with others reported in the literature.
Two cases of regional odontodysplasia in girls are reported; one affected the lower incisors, and the other the left maxilla. The first case was radiographically followed over a 6-year period, during which time the ghost teeth exhibited significant dentin formation, along with a resultant decrease in pulp size and relative normalization of the radicular anatomy. The second case involved the deciduous molars and the first permanent molar. In addition to tooth alterations, both cases exhibited many odontogenic epithelial islands and extensive areas of calcification in the mucosa. Diagnosis, causes, and treatment are discussed in the light of recent data.
OBJECTIVE: This study compared panoramic and intraoral radiographic surveys in the evaluation of specific dental pathoses in Air Force personnel. STUDY DESIGN: The radiographs of 30 subjects were read singly and in various combinations: panoramic survey only; periapicals plus bitewings; panoramic survey plus bitewings; and panoramic survey plus periapicals plus bitewings. Three independent, blinded examiners using standardized viewing conditions assessed the radiographs in random order for the presence of caries, periapical pathoses, bone loss, furcation involvement, impacted/unerupted teeth, internal/external root resorption, and retained roots. The consensus radiographic standard of true pathosis was the simultaneous interpretation by the three examiners of all radiographs for each subject. RESULTS AND CONCLUSIONS: The panoramic survey by itself was shown to have the lowest correlation with the consensus radiographic standard when basic military trainees with generalized dental pathoses were evaluated. The combination of panoramic survey plus bitewing radiographs exhibited a diagnostic yield for specific pathoses that was comparable to that of panoramic survey plus bitewings plus periapicals.
Amelogenesis imperfecta, a group of hereditary conditions primarily affecting the enamel, has been associated with dental anomalies, including taurodontism, congenitally missing teeth, delayed eruption, crown resorption, and abnormal enamel density. The purpose of this study was to assess the prevalence of these anomalies in an amelogenesis imperfecta population. The study group consisted of members of 9 unrelated families--22 family members with amelogenesis imperfecta and 13 unaffected family members. Panoramic radiographs were evaluated for taurodontism, congenitally missing teeth, delayed tooth eruption, pathologic dental resorption, pulp calcification, and radiographic enamel density. The prevalence of taurodontism was similar in people with amelogenesis imperfecta and normal people; all of the remaining parameters were more commonly observed in people with amelogenesis imperfecta. The radiographic enamel density was quantitatively reduced in teeth affected by amelogenesis imperfecta in comparison with teeth with normal enamel. These findings suggest that some of the features associated with amelogenesis imperfecta result from abnormal enamel formation (eg, decreased enamel density, crown resorption) whereas others may occur as a result of expression of the genetic mutation in cells other than ameloblasts (eg, abnormal eruption, pulp calcification).
Primary failure of tooth eruption rarely occurs. This case represents a rare clinical situation and appears to reflect a generalized disturbance in the eruptive process, inasmuch as (1) deciduous and permanent dentition are affected, (2) incisors, molars, and premolars are involved in all quadrants, (3) skeletal and craniofacial growth are within normal limits, and (4) no systemic/genetic anomalies were detected. This is the first such case reported in the literature; diagnosis and management are discussed.
Osteoclasts are multinucleated cells with the specialized function of resorbing calcified tissues. These cells develop from hemopoietic cells of the monocyte-macrophage lineage with the support of osteoblasts/stromal cells. Tooth eruption is a vertical movement of teeth via creation of an eruption pathway in and through the alveolar bone. The precise cellular and molecular determinants of tooth eruption are not yet clear, and a cell culture system that can reproduce the activity of osteoclast formation during tooth eruption is expected to be a useful tool to clarify the mechanism of eruption pathway formation. To this end, mandibular bodies, including incisors and molars, were isolated from 9- to 11-day-old mice undergoing active tooth eruption. Primary cells were obtained from mandibular bodies by enzymatic digestion and cultured in alphaMEM containing 15% FBS without any cytokine or growth factor or hormone in the culture (AFT culture, for alveolar bone, dental follicle, and tooth). A progressive increase in the number of tartrate-resistant acid phosphatase-positive multinucleated osteoclastic cells was observed in AFT culture. The osteoclastic cells generated were immunopositive for cathepsin K and calcitonin receptor, and formed resorption pits when cultured on dentine slices. Parathyroid hormone-related protein (PTHrP), expressed by the enamel organ of tooth, is reported to be an essential factor in creation of the eruption pathway. To verify this point, cells were isolated from mandibular bodies from which all teeth and dental follicles had been removed and cultured similarly (A culture, for alveolar bone). Osteoclastic cells were not formed and PTHrP production was hardly detected in the medium of A culture, in contrast to the high level of PTHrP in AFT culture. Since our previous study demonstrated that neonatal homozygous PTHrP-knockout mice show impaired osteoclastogenesis around tooth germs, AFT culture was performed by using this sample to examine whether this culture system can reproduce the status of osteoclastogenesis observed in vivo. The result showed that none of the osteoclastic cells were generated from cells of homozygous mice. We here report a novel mouse osteoclast culture system that reproduces the activity of osteoclast formation around erupting teeth without addition of any cytokine or growth factor or hormone to the medium. Histological examination of various transgenic and mutant mice now offers valuable findings on studies of tooth eruption and the present culture system using these animals would be a powerful tool in clarifying the cellular and molecular mechanisms of eruption pathway formation.
A case of a large dentigerous cyst containing a canine tooth in the maxillary antrum is presented. This case is of interest due because of its extensiveness and the presence of a canine tooth in the roof of the maxillary sinus. In addition, this caused a right-sided epiphora. Enucleation of the cyst containing the ectopic tooth was made.
Decision analysis is used to compare the cost and disability of alternative treatment strategies for asymptomatic mandibular third molars. The analysis shows that extracting only those third molars that remain impacted and become pathologically involved is always associated with less expected cost and disability than prophylactic removal of asymptomatic wisdom teeth.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The removal of the incipient canine teeth ('germectomy') in small babies is a practice carried out in many parts of eastern Africa. This article describes how 'germectomy' among the Jop'Adhola in Eastern Uganda is an important idiom of distress, referred to as false teeth by English speaking people, and lakijo marach (bad teeth) or gira kwanya (that which is removed) in the local language Dhop'Adhola. Through an analysis of how the notion of false teeth is shaped by macro social forces of war and poverty as well as by negotiations within the local social world, the discussion is taken beyond the question of cultural belief. False teeth as a practice seems to have spread through vast geographical areas within a few decades, but as the example of the Jop'Adhola shows, it has taken a particular social course in eastern Uganda--as it is most likely to also have done everywhere else it has gained a footing. By analyzing its social course we may gain insight into important mediating social processes which may have as much to do with actual health outcome in a particular area as health care per se.
OBJECTIVES: To compare the predicted tooth width measurements of permanent canine and premolars from Tanaka-Johnston regression equations and Moyers probability tables with the in situ measurements in a sample of Peruvian adolescents. DESIGN: Cross-sectional. SETTING AND SAMPLE POPULATION: Trujillo, Peru; 248 dental casts were measured using a sliding caliper with a Vernier scale rounded to 0.1 mm. RESULTS: Tanaka-Johnston regression equations were not precise, except for the upper arch in the male sample. For females, the Moyers 95th percentile in the upper arch and the 65th percentile in the lower arch predicted the sum precisely. For males, the Moyers 65th percentile for the lower arch predicted the sum precisely, but none of the Moyers percentiles provided precise prediction in the upper arch. CONCLUSIONS: Using tooth width prediction methods from a different racial origin could create an under- or overestimation of the actual combined canine and premolar tooth width, although their clinical significance is disputable.
A Japanese girl was referred to Osaka University Dental Hospital for examination of a tooth-like structure that had erupted following spontaneous exfoliation of a natal tooth in the lower left primary central incisor region. The structure had erupted at 6 months of age, and radiographic and clinical examination showed composition of pulp and dentin, but no enamel. On histological examination, the majority of the dentin area had a tubular dentin-like appearance, while the outer area of the root appeared to be composed of an osteodentin-like substance. Most of the dentin was covered by cementum. These findings suggest that the structure had originated from a developing remnant of the extracted natal tooth, which must have remained in the gingival tissues. We termed this calcified structure a residual natal tooth.
Following a severe traumatic incident to permanent immature teeth, the growth of calcified tissue in the pulp space may occasionally occur. This calcified tissue may be diffuse or in intimate contact with the dentine. It has been suggested that a wide open apex, severe damage to the root sheath, and the absence of infection are only some of the predisposing factors leading to this metaplasia of pulp tissue into bone-like tissue. Five cases are described.