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Results for “BLOOD ALKALINE PHOSPHATASE”

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At least 667 records · Page 37Linked to original sources
PubMed1983

[Alkaline phosphatase activity and isoenzymes in the blood serum of cattle, sheep and swine].

Studied were the total activity and the type of isoenzymes of the alkaline phosphatase in blood serum of cattle, sheep, and swine at various ages and different physiologic status. With all three species the enzyme activity showed explicit age dynamic. In month-old calves the activity of the serum phosphatase was 82.8 IU, on an average, and in adult cows--32.2 IU. In month-old lambs the enzyme activity was 310.6 IU, on an average, while in adult sheep it was 62.0 IU. In young pigs it ranged up to 105.0 IU, and in adult swine--up to 32.4 IU. No statistically significant differences in the enzyme activity was established between dry and lactating cows and ewes as well as between rams, boars, and sows. The study on the isoenzymes of the alkaline phosphatase (thermostability, specific chemoinhibitors, and electrophoresis in agar gel) revealed that in month-old calves there was only a bone isoenzyme in the blood serum; in calves that were more advanced in age there appeared also the liver and the intestinal isoenzymes, while in adult cows the intestinal or the liver enzyme of alkaline phosphatase was present only. The blood serum of lambs up to the sixth month of age contained the bone and the intestinal isoenzymes, and that of adult sheep--the liver and the intestinal ones. In pregnant sheep there were even low amounts of the placental isoenzyme of alkaline phosphatase. In pigs up to the sixth month of age the serum phosphatase was shown to be of bone origin, while in the adult swine--chiefly of liver origin.

Aging↗
PubMed1985

[Alkaline phosphatase in human lymphocytes. I. Cytochemical detection of alkaline phosphatase in normal human peripheral blood lymphocytes].

The present paper deals with a sensitive cytochemical method of identifying alkaline phosphatase (AP) in rosette-forming lymphocytes gained from the peripheral blood of healthy human beings. The percentage of AP-positive lymphocytes amounts to 5%, with all cells comprising B- and O-lymphocyte population and with T-lymphocytes being negative. In a group of healthy test persons, recently, however, having undergone various inflammatory processes or virus diseases, the number of AP-positive lymphocytes is significantly higher, from 41-73% in B- and O-lymphocytes and from 6-38% in T-lymphocytes. This observation indicates that AP in lymphocytes may have a clinical significance in reactive lymphoproliferative processes, which must be elucidated by further investigations.

Adult↗
PubMedDate not supplied

The influence of furfural inhalation poisoning on calcium and phosphorus metabolism in rats.

The inhalation of furfural, 20 mg/m3 by adult rats during 3 months for 5 h daily, 6 times a week, did not change the calcium and phosphorus level in blood serum and in bones, but depressed the activity of alkaline phosphatase in blood serum. The exposure to furfural of immature rats (6-7 weeks old) during 4 weeks caused a depression of blood serum and intestine mucosa alkaline phosphatase activity, elevation of calcium and phosphorus levels in blood serum with concomitant fall in bones, and a decrease in calcium excretion with urine.

Animals↗
PubMed1978

Skeletal blood flow in Paget's disease of bone and its response to calcitonin therapy.

1. Blood flow to the skeleton was measured by the 18F clearance method of Wooton, Reeve & Veall (1976) in 24 patients with untreated Paget's disease. In every patient but one, resting skeletal blood flow was increased. There was a significant positive correlation between skeletal blood flow and serum alkaline phosphatase and between skeletal blood flow and urinary total hydroxyproline excretion. 2. Fourteen patients were re-studied after they had received short-term (7 days or less) or long-term (7 weeks or more) calcitonin. Skeletal blood flow, alkaline phosphatase and urinary hydroxy-proline excretion fell towards normal in every case. There was some evidence from the short-term studies that calcitonin produced a more rapid fall in skeletal blood flow than in alkaline phosphatase. 3. Glomerular filtration rate appeared to increase transiently in response to calcitonin.

Alkaline Phosphatase↗
PubMed1979

Report of a working group for the European Pharmacopoeia. Collaborative assay on human albumin of different origin.

A collaborative assay was conducted by 9 laboratories on 31 samples of human albumin which were in clinical use. It was the object of the study to establish test systems which would differentiate between albumins of venous or placental origin. The properties examined for this purpose were: appearance, total protein, haem, polymers, alkaline phosphatase and blood group substances. Additional tests such as for beta-thromboglobulin and citrate were included; pyrogenicity, however, was excluded because this was under study for all plasma proteins at that time. Results obtained were in satisfactory agreement both between laboratories and between samples. They, therefore, enabled the verification of a number of correlations in the test systems. The evaluation did not allow, however, the differentiation of the samples in relation to their origin. The results were, therefore, regarded as a tool to define the upper limits of acceptance for human albumins corresponding to the quality prescribed by the European Pharmacopoeia.

ABO Blood-Group System↗