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Magnetic resonance imaging of intracranial aneurysms.

Intracranial aneurysms are lesions with high morbidity and mortality, but in most cases represent treatable disease. Magnetic resonance (MR) imaging and in some cases MR angiography can make valuable contributions to their diagnosis and characterization. The ultimate tool for imaging these lesions, however, remains catheter angiography. This article focuses on saccular aneurysms, with a brief discussion on atherosclerotic fusiform aneurysms and mycotic aneurysms.

Aneurysm, Infected↗

Characterization of plasma lipoproteins in survivors of cerebral infarction.

To characterize the plasma lipoproteins in survivors of cerebral infarction, plasma lipoproteins were ultracentrifugally fractionated into VLDL, LDL, HDL2 and HDL3, and the concentrations of cholesterol, phospholipid, apolipoprotein and triglyceride in each lipoprotein class were determined. Subjects examined were 15 male healthy controls and 15 male survivors of cerebral infarction situated in the distribution of cerebral cortical artery. The concentrations of VLDL-cholesterol and VLDL-triglyceride and the percent content of VLDL-cholesterol were higher in survivors than in controls. The concentration of LDL-triglyceride was higher and the percent content of LDL-cholesterol was lower in survivors than in controls. While the plasma concentration of triglyceride was higher in survivors than in controls, those of HDL, HDL2 and HDL3 were lower in survivors. The concentrations of cholesterol, phospholipid and apolipoprotein in either HDL2 or HDL3 were also reduced in survivors as compared with controls. In either HDL2 or HDL3, the percent content of triglyceride was higher and that of phospholipid was lower in survivors than in controls. These results were in good agreement with those reported for survivors of myocardial infarction, suggesting that the underlying derangement in lipoprotein metabolism is common to myocardial and cerebral infarction.

Adult↗

Procaine (novocain) treatment of patients with senile and arteriosclerotic brain disease.

Of 32 patients (13 men and 19 women) with a mean age of 81.1 years committed to a mental hospital for senile or arteriosclerotic psychoses, 11 received 2% procaine hydrochloride according to Aslan's method, for an average of 13 months, 11 for 6 months, and 10 normal saline. Of 20 patients, with a mean age of 72 years, who attended the geriatric psychiatric clinic of a general hospital, 10 were treated with procaine hydrochloride and 10 with normal saline for six months. Procaine hydrochloride applied for six or 12 months did not appreciably alter the symptomatology and course of senile and arteriosclerotic brain disease. It did not improve the senile amnestic syndrome or neurological symptomatology, when present. The general mood and level of activity improved temporarily. It was also temporarily helpful in alleviating depressive symptoms in patients suffering from arteriosclerotic brain disease.

Aged↗