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[The problem of specificity of osteoarticular neoplasms based on topography].
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Giant-cell tumor of bone. An analysis of two hundred and eighteen cases.
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Non-osteogenic fibroma of bone.
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[Results of the use of Sr-85 isotopes from the viewpoint of bone pathology].
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Ewing's sarcoma with diffuse involvement of the bone marrow (report of two cases).
The author reports two cases of Ewing's sarcoma with diffuse neoplastic invasion of the bone marrow causing panmyelopoietic failure. This condition must be differentiated from the medullary aplasia which may occur as a complication of treatment of antitumoral chemotherapy in patients affected by Ewing's sarcoma.
Histiocytic fibroma of bone (a study of 170 cases).
This study is based on 170 cases of histiocytic fibroma of bone. This is a metaphyseal hamartoma composed of histio-fibroblasts; it is completely benign, and affects children and adolescents. Because of their benign nature and characteristic radiographic appearance, which is almost always diagnostic, these tumours do not require surgery, except in rare forms that give rise to symptoms, or in which tthe radiographic appearances are atypical and clarification of the diagnosis is called for.
[Malignant double tumors in women].
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Appendicular skeletal tumours coined by odontogenic terms.
Two intriguing tumours in the appendicular skeleton are coined by odontogenic terms: the "adamantinomas" and "cementomas" (or "cementifying fibromas"). Both are extremely rare, mainly the latter. Eight verified observations are presented here: five adamantinomas and three cementomas. Whereas in adamantinomas, the localization and radiographic picture was very typical in all cases, only one cementoma was found in the metaphysis of a long tubular bone in our survey. Diaphyseal tibial localization in one, and metacarpal in the another patient are the first two atypical localizations, described for this tumor in the world's medical literature. Angiography is characteristic for a benign expansive lesion and should be carried out in all cases. An "en bloc" resection is the intervention of choice for both these entities.
Computed tomography of orthopedic tumors of the pelvis and lower extremities.
An analysis of 6 representative cases of tumors of the pelvis and lower extremities demonstrates the clinical usefulness of computerized tomography (CT) in preoperative evaluation. CT provides information regarding precise size of the mass, its location and relationship to muscle bundles and fascial planes, definition of the margins of the mass, relation to neural, vascular and bony structures not previously available by plain film and angiography. This information is of particular value to the orthopedic surgeon in evaluating the feasibility of en bloc resections of tumors and in planning reconstructive procedures.
[Computed tomography of primary bone tumors in children].
The diagnostic value of CT examination in 21 children with 14 malignant and 7 benign bone neoplasias was evaluated. CT contributed in 72%; mainly in malignant conditions it was superior to other diagnostic techniques and demonstrated the exact intra- as well as the extraosseous extension. The cross sectional display facilitated evaluation of complex anatomic structures. Monitoring the treatment was easily performed by CT follow-up studies. However, 28% of all the examinations were not contributary, this group mainly including benign lesions.
[Treatment of osteogenic sarcoma in childhood].
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[Skeletal metastasis of osteosarcoma].
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[Our experience with endoprosthesis in surgery for bone tumors].
Endoprosthesis is a method allowing a valuable substitution of bone defects (articular ends of long tubular bones, both articular ends of the bones making the articulation, whole long tubular bones with articulations). The employment of endoprostheses is expedient for the substitution of defects of the breast bone, pelvis, hand bones as well. Endoprosthesis in combination with preoperative radiotherapy and post-operative modern chemotherapy allows preserving the extremities in certain patients with osteogenic sarcoma, chondrosarcoma, reticulosarcoma, chondrosarcoma and solitary plasmacytoma. The experience with 204 operations of endoprosthesis of bones is presented.
[Mesenchymal chondrosarcoma (clinico-morphological study)].
Mesenchymal chondrosarcoma was found in 11 out of 161 patients with chondrosarcoma of the bone. The assaultive nature of the disease is illustrated by the following data: the period between the manifestation of symptoms and the first visit to the doctor was 5.9 +/- 4.3 months; metastases were detected within 20.56 +/- 6.04 months and 8 patients out of 10 died within the first 5 years. Two histological structures were observed: those of the chondrosarcoma type and hemangiopericytoma-like structures formed of small atypical cells.
[Hemophilic pseudotumor (considerations on 2 cases)].
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[Our experience with the treatment of osteogenic sarcoma (author's transl)].
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[The cementless implantation of tumor endoprostheses (author's transl)].
Due to the improved prognosis of patients with primary malignant bone tumours, permanent attachment is also one of the problems encountered in the implantation of tumour endoprosthesis without bone cement, as surgeons are at present attempting to do in the case of conventional joint endoprostheses. The two methods which can be used for the cementless implantation of tumour endoprostheses are intramedullary stem fixation and extracortical attachment. Both methods require additional stabilisation by plates. Mechanical loading tests on 90 pairs of anatomical femurs showed that all the forms of attachment investigated exhibited adequate primary stability. However, it would appear necessary to fix two securing plates laterally and ventrally in order to achieve stable permanent attachment. The clinical results so far obtained with 18 cone endoprostheses and 12 stem endoprostheses are satisfactory. In the case of cone endoprostheses observed for an extended period after insertion, radiological checks showed the "incorporation" of the implant as an indication of stable permanent attachment. Radiological checks of patients with stem endoprostheses showed considerable structural movement in the area of the attachment. However, this did not result in signs of loosening so far. At the present time the cone attachment is preferable in view of the simpler operating technique involved and the more favourable radiological observations following the operation.