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At least 667 records · Page 37Linked to original sources
PubMed1975

Treatment of hyperparathyroidism by percutaneous embolization of a mediastinal adenoma.

Percutaneous embolization of parathyroid adenomas was attempted in three hypercalcemic patients with previously unsuccessful neck explorations. Two adenomas were in the mediastinum and the third was within the thyroid lobe. Autologous clot, Gelfoam, and silicone rubber were used to obstruct feeding arteries. The intrathyroidal adenoma failed to respond but both mediastinal adenomas were infarcted. Hyperparathyroidism recurred after 7 months in one patient but the other remains normocalcemic 8 months postembolization.

Adenoma↗
PubMed1975

Gelfoam embolization of the left gastric artery for bleeding ulcer: experimental considerations.

A bleeding gastric ulcer was surgically created in 18 dogs, and the left gastric artery was successfully catheterized by percutaneous techniques in 15. Nine of these dogs were treated with vasopressin infusion which did not arrest the hemorrhage. A total of 11 dogs (five of them following unsuccessful vasopressin therapy) underwent embolization with strips of Gelfoam, and hemorrhage stopped in ten. This technique of embolization is concluded to be of value in the management of gastric hemorrhage.

Angiography↗
PubMed1976

Intraluminal obliteration of the renal arteries in kidney tumors.

A preoperative obliteration of the renal vascular bed was performed in 90 patients by means of Gelfoam emboli. This procedure facilitates the ligation of the renal vein and artery during transabdominal nephrectomy. The decreased vascularity lessens the risk of tumor embolization and reduces the duration of the surgical procedure by half. A simple routine percutaneous method of occlusion is described. Gelfoam emboli are unsuited for permanent obliteration in bleeding tumors.

Adult↗
PubMed1977

Therapeutic embolization for intractable chronic bleeding.

Intractable, chronic vaginal and/or vesicle bleeding complicating pelvic cancers in five women was treated by transcatheter embolization of the hypogastric artery or its branches. Bleeding was presumed to be from hypervascular granulation tissue formed in response to irradiation in two patients and from tumor tissue in three. The embolic materials were Gelfoam and Oxycel reinforced autologous clots. Bleeding was stopped or reduced in volume by at least 90% in each patient. This form of therapy was useful even though bleeding site was not demonstrated angiographically.

Chronic Disease↗
PubMed1977

New techniques for interruption of gastroesophageal venous blood flow.

Enlarged gastroesophageal veins were successfully obliterated in 41 patients using embolization with modified autogenous clots and/or Gelfoam, balloon occlusion, iatrogenic perivenous hematoma, sclerosing agents (Sotradecol and Keflin), or a combination of these methods. Thirteen patients were actively bleeding when studied, and the site of bleeding was detected in 4. Surgical exploration of 16 patients and autopsy study of 5 showed persistent obliteration ranging between three weeks and seven months. No major complications requiring reparative surgery were encountered. Gelfoam soaked with Sotradecol is the preferred agent because it provides persistent obliteration of the embolized veins. Patients who are acutely bleeding or have done so previously are candidates for selective obliteration of the gastroesophageal veins.

Catheterization↗
PubMed1977

Transcatheter splenic arterial occlusion: an experimental study in dogs.

Three techniques of transcatheter splenic arterial occlusion were evaluated in dogs. Angiographic, hematologic, and morphologic studies were done up to 9 weeks postocclusion. All animals showed hematologic changes characteristic of depressed splenic function; the degree and duration of these changes depended upon the technique. Alterations in histology including vascular congestion, infarction, and fibrosis, were also dependent upon the method used and the time elapsed after occlusion. Celiac angiography demonstrated the extent of collateral circulation and degree of recanalization of the occluded vessels. Potential clinical applications are discussed.

Angiography↗
PubMed1977

Catheter therapy: fluoroscopic monitoring of deliberate embolic occlusion.

In the deliberate embolic occlusion of arteriovenous malformations (AVM's and vascular tumors, complications can occur when emboli pass into arteries supplying normal structures. Maximum safety and precision is gained by direct fluoroscopic visualization of the occlusion process done by suspending the particles in a contrast agent and monitoring the ever-decreasing vessel runoff. The technique has been useful in the treatment of intra- and extracranial AVM's and tumors.

Arteriovenous Malformations↗
PubMed1978

Partial embolization of large peripheral hemangioma for pain control.

Pain associated with a large hemangioma of the thigh was relieved by embolization of a portion of the lesion with Gelfoam. The branch to be occluded was selected when the distribution of the heat associated with the injection of contrast material corresponded to the distribution of the patient's pain.

Adult↗
PubMed1978

Gelfoam embolization of the kidneys for treatment of malignant hypertension.

Some chronic renal failure patients maintained on dialysis have uncontrollable hypertension. Those with elevated renin levels require bilateral nephrectomies prior to kidney transplant to avoid nephrosclerosis. The morbidity and mortality from surgical nephrectomies are high. In 2 such patients we embolized the renal arteries with gelfoam and successfully occluded all the major vessels. One patient became normotensive. The second remained hypertensive and had increased renin levels, probably on the basis of ischemia. Subsequent surgical nephrectomies demonstrated completely occluded segmental branches but only focal areas of infarction. Collateral blood supply determines the success of the procedure.

Adult↗
PubMed1979

Transcatheter arterial occlusion in the management of rectosigmoidal bleeding.

Transcatheter arterial occlusion was performed in five patients with recurrent rectosigmoidal bleeding. Four had malignant neoplasms, and the fifth, an arteriovenous malformation. The superior hemorrhoidal artery was embolized in two patients, the inferior mesenteric artery in two, and the left internal iliac artery in one patient. In four patients, immediate and complete control of rectal bleeding was achieved, and gradual control was accomplished in the fifth patient. Left lower quadrant pain and fever developed in three patients. The possibility of rectosigmoidal bleeding from the internal iliac artery is stressed.

Adult↗
PubMed1979

Arterial occlusion in the management of pain from metastatic renal carcinoma.

Arterial embolization was performed in nine patients with metastases from renal carcinoma who had severe pain resistant to conventional therapy. Patients with metastases in the ilium (four), the lumbosacral spine (one), and the base of the skull (one) experienced pain relief lasting from one to six months. The other three patients, who had metastases in the proximal femur, underwent preoperative embolization to facilitate tumor curettage and internal hip fixation. No significant complications were seen with this therapeutic approach.

Aged↗
PubMed1975

Transcatheter arterial embolization in the management of bleeding in the cancer patient.

Selective transcatheter arterial embolization was performed in 7 cancer patients with gastrointestinal or uterine bleeding. Most were bleeding from neoplastic tissue and were refractory to conservative management. Complete and permanent cessation of bleeding was obtained in 5 patients, including 3 with gastric bleeding, 1 with colonic bleeding, and in 1 with uterine bleeding. Successful arterial embolization allowed further treatment of the underlying disease which was particularly critical as these patients were poor surgical candidates. No significant or prolonged side effects were noted.

Adult↗
PubMed1975

Nonsurgical treatment of arteriovenous malformations of the trunk and limb by transcatheter arterial embolization.

Two patients with large arteriovenous malformations (AVM) were successfully treated by transcatheter selective arterial embolization with Gelfoam. An extensive lumbar retroperitoneal acquired AVM was markedly reduced, eliminating any clinical evidence of a persistent left-to-right shunt. A large localized congenital AVM of the thigh in the second patient completely disappeared. Transient post-procedure fever developed in the first patient. Prolonged fever and pulmonary infarction complicated the second case with complete recovery in three weeks. The advantages of Gelfoam as an embolizing agent are discussed. The technique appears to be a reasonable alternative to extensive and sometimes mutilative surgery.

Adult↗
PubMed1989

Transrenal ureteral occlusion with Gianturco coils and gelatin sponge.

The authors report the use of Gianturco coils and gelatin sponge plugs to achieve complete occlusion of nine ureters in five patients with advanced pelvic malignancies and lower urinary tract fistulas. The method is simple to apply, is readily available, and to date has been associated with no significant complications. These results suggest that, before more elaborate methods of ureteral occlusion are applied, the use of coils and gelatin sponge should be considered as the primary method of ureteral occlusion. Further work is needed to elaborate the exact mechanism by which these materials cause occlusion.

Embolization, Therapeutic↗
PubMedDate not supplied

Complications associated with transcatheter arterial embolization for hepatic tumors.

Transcatheter arterial embolization (TAE) is widely used in the treatment of hepatic tumors. A total of 2,300 TAE procedures were performed with a 2-15-mL injection of a mixture or suspension of anticancer drugs and iodized oil, followed by administration of gelatin sponge particles. One or two chemotherapeutic drugs, including doxorubicin hydrochloride (10-30 mg), epirubicin hydrochloride (10-30 mg), mitomycin C (10-20 mg), and cisplatin (25-100 mg), were used for each procedure. Complications were encountered in 4.4% of cases (n = 102) and were related to the use of chemoembolic agents or the manipulation of a catheter or guide wire. These complications included acute hepatic failure (n = 6), liver infarction (n = 4) or abscess (n = 5), intrahepatic biloma (n = 20), multiple intrahepatic aneurysms (n = 6), cholecystitis (n = 7), splenic infarction (n = 2), gastrointestinal mucosal lesions (n = 5), pulmonary embolism or infarction (n = 4), tumor rupture (n = 1), variceal bleeding (n = 3), and iatrogenic dissection (n = 35) or perforation (n = 4) of the celiac artery and its branches. Knowledge of these complications is important for correct diagnosis and appropriate management.

Angiography↗