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PubMedDate not supplied

Recurrent spontaneous abortion: state of the art and new horizon.

Spontaneous abortion is the commonest complication of pregnancy and its frequency has been estimated to be between 15 and 20% of all clinical pregnancies. A comprehensive classification of etiologic factors that may cause repeated abortions is made and the importance of a precise program of the necessary diagnostic steps is underlined.

Abortion, Habitual↗
PubMed1987

Experimental infection and abortion of pregnant guinea pigs with a unique spirillum-like bacterium isolated from aborted ovine fetuses.

Study was made of the pathogenicity of a spirillum-like, anaerobic, gram-negative bacterium, originally isolated from aborted lambs, for pregnant guinea pigs. Reproducible conditions for propagation and preservation of the bacterium were determined as requisite for the preparation of cultures for animal inoculation. A preliminary experiment was done with 10 pregnant guinea pigs to test for an infective dose of organisms that would produce abortion. High-passage cultures (n = 50) were used to inoculate these guinea pigs intraperitoneally. Six of 10 guinea pigs aborted, and the organism was cultured from fetal tissues of 5 guinea pigs. Isolates from 3 of the 6 guinea pigs were propagated through 4 passages on blood agar and used to infect 3 groups, each of 5 guinea pigs. A 4th group of 5 guinea pigs was inoculated with the original culture. Three of 5 animals in the first 3 groups, which had been given the low-passage cultures from the preliminary trial, and 2 of 5 guinea pigs in the 4th group, which had been given the original culture, aborted. Antibody against the spirillum was detected in 19 of 30 inoculated guinea pigs. The major microscopic lesions were acute suppurative placentitis and splenitis. This bacterium retained pathogenic properties sufficient to cause infection, abortion, and microscopic lesions in two-thirds of the guinea pigs, in spite of high in vitro passage. The organism has unique ultrastructures, and its genus and species are yet to be determined.

Abortion, Veterinary↗
PubMed1985

Pregnancy-associated group B streptococcal endocarditis: a report of two fatal cases.

Group B streptococci commonly colonize parturient women, yet pregnancy-associated endocarditis due to this organism is rare. Most reports of group B streptococcal endocarditis are from the preantibiotic era and occurred in women with rheumatic mitral valve disease. Reported herein are two cases of fatal group B streptococcal endocarditis involving the aortic valve of women with no preexisting heart disease. One had undergone a second-trimester abortion and the other had a normal pregnancy and uncomplicated vaginal delivery.

Abortion, Induced↗
PubMedDate not supplied

Rubella in the United Kingdom, 1970-1983.

The numbers of acquired and congenital rubella infections in the United Kingdom were obtained from clinical and laboratory reports and from notifications to the National Congenital Rubella Surveillance Programme. Since 1970 the annual frequency of clinical infection has varied from 150 to 450 cases per 100,000 population and laboratory reports of infection, from 800 to 4,100 per year. The number of notified congenital rubella infections varied from 12 to 86 per year. The largest recent epidemics occurred in 1978 and 1979, with an increase in the number of congenital rubella infections during the following winters. Increased numbers of cases occurred every one to three years, with troughs of two to three years, but peaks in different localities often did not coincide. Terminations of pregnancy associated with rubella or rubella vaccination during pregnancy are reported by the Office of Population Censuses and Surveys and vary with the incidence of acquired rubella; a maximum of 830 abortions were performed in 1978 for women who acquired the disease, and from 27 to 156 were performed each year for women vaccinated just before or soon after becoming pregnant. The effect of the vaccination program is discussed in relation to the decrease in the number of young women without rubella antibody.

Abortion, Induced↗