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[Ischemia after intramuscular injection of benzathine penicillin].

Two cases of ischemia produced by arterial spasms following an intragluteal injection of benzathine-penicillin which have been solved successfully are reported. Authors review literature on this subject and warn of the serious problems that may happen with this procedure.

Buttocks↗

Pharmacokinetics of amikacin in pony foals after a single intramuscular injection.

Six healthy pony foals, from 2 to 11 days of age, were given a single IM injection of amikacin sulfate (250 mg/ml) at a dosage rate of 7 mg/kg of body weight. Serum amikacin concentrations were measured serially over a 24-hour period. The mean peak serum concentration was 14.7 micrograms/ml at 0.5 hour. The elimination rate constant for amikacin was 0.24/hour, the elimination half-life was 3.0 hours, and the apparent volume of distribution was 0.58 L/kg.

Amikacin↗