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Results for “Retinal Detachment”

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At least 667 records · Page 37Linked to original sources

PubMed1994

Experimental transient exudative retinal detachment in the rat.

OBJECTIVE: To establish a new model of exudative retinal detachment in the rat. METHODS: Photothrombosis was produced in a single retinal vein using direct treatment with a dye laser operating in the yellow wavelength (577 nm). Control eyes received identical laser applications, but treatment was placed alongside the vessel and photothrombosis was not produced. Eyes were examined at intervals during the subsequent week with ophthalmoscopy, photography, fluorescein angiography, and light microscopy. RESULTS: In 13 (41%) of 32 eyes with photothrombosis, bullous retinal detachments developed 1 day after laser treatment, and continued occlusion of the vein was confirmed with fluorescein angiography. Detachments persisted for 2 to 4 days and spontaneously resolved; resolution coincided with restored venous patency at 5 to 7 days. None of the 20 control eyes developed bullous detachments (P < .005). CONCLUSIONS: Laser photothrombosis in the rat offers a simple and accessible model of transient exudative retinal detachment without the need for exogenous chromophores.

Animals↗

PubMed1997

[Scanning electron microscopy (SEM) of subretinal fluid in idiopathic retinal detachment].

PURPOSE: To evaluate the cells of subretinal fluid (SRF) by the use of the scanning electron microscope and to determine relationships between morphologic features of SRF and duration of retinal detachment. MATERIALS AND METHODS: Subretinal fluid was taken from 7 patients with retinal detachment. The cytologic preparations were analyzed in electron scanning microscope (IEOL). RESULTS: The highest count of cells (predominantly macrophages and lymphocytes) were seen in SRF obtained in the third week after retinal detachment. Retinal detachment, which lasted more than 3 weeks, caused lower SRF cells count and changes in cells composition. After 6 months normal cells were not present in SRF.

Adult↗

PubMed1989

Pseudophakic retinal detachment after YAG laser capsulotomy.

Eighteen eyes that developed pseudophakic retinal detachment after YAG laser capsulotomy were reviewed. There did not appear to be any relationship to the energy used, or the size of the capsulotomy. The majority of eyes had only one retinal break and these were located superior-temporally two-thirds of the time. High-risk characteristics for post-YAG retinal detachment included high myopia, lattice degeneration, and retinal detachment in the fellow eye.

Humans↗

PubMed1986

The role of induced choroidal retinal adhesion in retinal detachment surgery.

The use of induced adhesion in retinal and vitreous surgery is considered. A follow-up report on a series of cases of retinal detachment treated with buckling only shows that there is a risk of late re-detachment from the original hole as the buckle height diminishes. Cryotherapy is therefore necessary to prevent redetachment but as it is not necessary for reattachment it is reasonable to confine its application to the immediate vicinity of the retinal hole. An adhesion is advised in most cases of retinal detachment treated by vitrectomy, exceptions being small holes at the posterior pole.

Choroid↗

PubMed2000

Formation of proliferative vitreoretinopathy in primary rhegmatogenous retinal detachment.

Proliferative vitreoretinopathy (PVR) is the only cause of ultimate failure following retinal detachment surgery. This study aimed to review the rate of postoperative PVR in a series of 186 consecutive patients with primary rhegmatogenous retinal detachments. All 186 detachments were repaired with a scleral buckling procedure combined with cryotherapy. Drainage of subretinal fluid was done at the discretion of the surgeon. The mean follow-up was 12 months. In this series 152 (82%) of primary detachments were repaired succesfully with a single operation. Sixty-eight percent of patients regained 0.3 or better visual acuity, and 3% of patients were left with visual acuity of 1/60 or less. After two or more operations the retina was attached in 96% of the cases. In 12 (6%) eyes PVR was responsible for the initial surgical failure. In 4 cases PVR (grade B and limited C) was present prior to surgery. In 3 cases PVR developed within 2 days postoperatively, in 3 cases after 3-6 weeks and in another 2 cases after 8-10 months. Eight out of 12 (66%) PVR patients had undergone cataract surgery. One PVR case had preoperative intraocular inflammation. An association between the duration of retinal detachment, or drainage of subretinal fluid and the development of PVR could not be demonstrated. In conclusion, the rate of postoperative PVR in primary rhegmatogenous retinal detachments was low. PVR preoperatively present and pseudophakia may be risk factors.

Cryotherapy↗

PubMed1998

Pneumatic retinopexy as supplemental therapy for persistent retinal detachment after scleral buckling operation.

PURPOSE: Persistent retinal detachment following scleral buckling may be caused by persistent open retinal tears with a large amount of subretinal fluid, despite proper positioning of the buckle. In this study we evaluated the effectiveness of supplemental pneumatic retinopexy in flattening of the detached retina. METHODS: During 1990-1994 twelve cases of persistent retinal detachment following scleral buckling operation with appropriate position of the buckle, underwent supplemental gas injection. RESULTS: Reattachment of the retina with complete absorption of the subretinal fluid was observed within 24-48 hours from the gas injection in all eyes. Three eyes redetached and required additional operations. At the end of the follow-up (mean 16 months) the retina was attached in all eyes, and the visual acuity was 20/120 or better in 11 eyes, and 20/30 or better in 7 eyes. No complications were observed. CONCLUSION: Pneumatic retinopexy for persistent retinal detachment, following scleral buckling, is effective in obtaining fast flattening of the retina and achieving good visual results.

Adult↗

PubMed2002

Retinal detachment in Marfan syndrome: clinical characteristics and surgical outcome.

PURPOSE: To describe the clinical characteristics of retinal detachments in patients with Marfan syndrome and report the surgical outcome of vitreoretinal surgery. METHODS: Records relating to 53 eyes of 45 patients with Marfan syndrome who underwent surgery for rhegmatogenous retinal detachment were reviewed. Of the 53 eyes, 24 (45.3%) underwent scleral buckling as the first procedure and 29 (54.7%) underwent vitrectomy surgery with scleral buckle as the first procedure. Main outcome measures included clinical characteristics of retinal detachment, reattachment rates, and functional improvement in vision. RESULTS: Characteristic findings included total retinal detachment in 40 (75.5%) eyes, atrophic holes in 24 (45.3%) eyes, more than four retinal breaks in 21 eyes (39.6%), preequatorial and postequatorial breaks in 20 (37.7%) eyes, giant retinal tears in six (11.3%) eyes, and proliferative vitreoretinopathy (posterior, anterior, or both) in nine (17%) eyes. In 30 (56.6%) eyes, retinal breaks were located only in the temporal half of the retina. Of the 24 eyes with myopia, 13 (54.2%) had a myopic correction greater than 7 diopters. At the median follow-up of 10.7 months, complete retinal reattachment was obtained in 87.6% and 86.2% of patients undergoing scleral buckling (including additional procedures such as vitrectomy) and vitrectomy surgery, respectively. In eyes with reattached retinas, a final visual acuity of 20/200 or better was obtained in 81% of the patients after scleral buckling and in 56% of the patients after vitrectomy surgery (P = 0.07). CONCLUSIONS: Retinal detachment in Marfan syndrome is complete in 75% of the eyes. More than half (56%) the eyes had a retinal break only in the temporal half of the retina, and 83% had at least a break in the temporal half of the retina. Currently available vitreoretinal surgical techniques result in successful reattachment of the retina in approximately 86% of the eyes.

Adolescent↗

PubMed1996

Retinal detachment complicating scleral-sutured posterior chamber intraocular lens surgery.

Although retinal detachment has been reported in association with sutured posterior chamber intraocular lenses (PCIOL), detailed analysis of the pathogenesis, clinical features and risk factors is lacking. Thirty-nine patients who had undergone surgery for scleral-sutured PCIOL were therefore reviewed, revealing 8 patients with associated retinal tears or detachments. Retinal breaks resulted from vitreous incarceration by the intraocular suture (6), post-operative vitreous detachment (1), preretinal manipulation of the dislocated PCIOL (1), surgical entry-sites (1) and surgical induction of posterior vitreous detachment (1). An axial length > 25 mm was associated with the development of retinal tears (p < 0.05, Fisher's exact test). All patients had attached retina with median visual acuity of 6/12 (range 6/6 to CF) at last follow-up (median 15 months, range 1-41 months). In patients requiring a pars plana approach, careful attention to the posterior hyaloid face, basal gel, surgical entry-sites and suture tract is recommended to reduce the risk of retinal detachment associated with scleral-sutured PCIOL procedures.

Adult↗

PubMed2000

[Thrombin-antithrombin III complexes in plasma and subretinal fluid in patients with perforated retinal detachment].

PURPOSE: To study the thrombin generation in plasma and subretinal fluid (SRF) by evaluation of thrombin-antithrombin III complexes (TAT) and antithrombin III (AT III) activity in patients with rhegmatogenous retinal detachment. MATERIAL AND METHODS: Prospective study of 54 patients subjected to retinal detachment surgery. Patients with vein or arterial disease and with other factors which could change evaluated parameters were excluded. Subretinal fluid samples were obtained at the time of routine drainage during retinal detachment surgery. Venous blood samples were taken from the cubital vein to natrium citrate solution (9:1) immediately after induction of anaesthesia but before surgery. TAT concentration in citrate plasma and in SRF was assessed in 22 patients aged from 15 to 78 years (mean: 49.5 years). AT III activity in blood plasma and SRF was measured in 32 patients aged from 20 to 77 years (mean: 53.8). The correlations between the TAT concentration in SRF were evaluated as well as AT III activity in SRF, and age, sex of patients, the duration and extent of retinal detachment, number of retinal tears and the cryopexy application. RESULTS: The median value of TAT concentration in citrate plasma was 9.08 micrograms/l (interquartile range: 59.3 micrograms/l). In 20 cases out of 22 eyes studied TAT levels were higher than 60 micrograms/l. The mean level of AT III activity in blood plasma was 105% (SD: 24.0%). The median level of AT III activity in 32 samples of SRF was 16.5% (interquartile range: 14.5%). The levels of AT III in SRF were significantly lower than AT III values in blood plasma (p < 0.001). We found no correlation between the levels of AT III activity in plasma and AT III activity in SRF nor between TAT concentration, AT III activity in SRF and sex, age of patients, the degree of myopia, the duration and extent of retinal detachment, nor retinal degenerative changes and cryopexy application. CONCLUSION: Our study revealed high TAT concentration and AT III activity and in all studied samples of SRF disclosing the signs of thrombin generation in SRF.

Adolescent↗

PubMed2005

The risk of fellow eyes in patients with rhegmatogenous retinal detachment.

PURPOSE OF REVIEW: A review of the current literature regarding the risk of nontraumatic rhegmatogenous retinal detachment in the fellow eye and prophylaxis of predisposing lesions is presented. RECENT FINDINGS: Although reports vary in study design and inclusion/exclusion criteria, the risk of retinal detachment in fellow eyes is similar to prior findings. Studies on prophylactic therapy also treated different cohorts. This makes drawing definitive conclusions difficult. SUMMARY: Rhegmatogenous retinal detachment poses a significant threat to the fellow eye. Risk factors specifically relevant to the fellow eye are discussed. There is insufficient evidence to recommend prophylactic therapy for prevention of retinal detachment in the fellow eye. To date, no prospective, randomized clinical trial on the prevention of retinal detachment in the fellow eye has been published.

Functional Laterality↗

PubMed1996

Risk factors for retinal detachment after cataract surgery. A population-based case-control study.

PURPOSE: Previous analyses of Medicare claims data, as well as clinical series, have suggested that performance of neodymium:YAG (Nd:YAG) laser posterior capsulotomy after extracapsular cataract surgery increases significantly the risk of retinal detachment. However, methodologic problems with previous research limit the strength of conclusions that can be drawn from these earlier studies. This study was designed to resolve those methodological limitations while using a population-based approach for assessment of the independent association between the performance of Nd:YAG laser posterior capsulotomy and pseudophakic retinal detachment. METHODS: A nested case-control study was conducted. Medicare beneficiaries who had undergone extracapsular cataract extraction from 1988 to 1990 were identified from a 5% sample of Medicare claims data. Within this cohort, people who were diagnosed or treated for retinal detachment during the years 1988 through 1991 (cases) were identified from Medicare records. Four controls were matched to each case of retinal detachment using an incidence density design. Providers of the patients' cataract and retinal surgery were contacted and asked to provide clinical data for all cases and controls that they had treated. RESULTS: Seven hundred six cases of retinal detachment were originally identified from Medicare records. After exclusions due to ineligibility, a total of 291 cases and 870 matched controls were available for analysis. Conditional logistic regression models showed that a number of factors were associated independently with an excess risk of retinal detachment after cataract surgery. These included Nd:YAG laser capsulotomy (odds ratio [OR] = 3.8; 95% confidence interval [CI], 2.4-5.9), a history of retinal detachment (OR = 2.7; 95% CI, 1.2-6.1), a history of lattice degeneration (OR = 6.6; 95% CI, 1.6-27.1), axial length (OR = 1.21/mm; 95% CI, 1.03-1.43), refractive error (OR = 0.92/diopter; 95% CI, 0.88-0.95), and a history of ocular trauma after cataract surgery (OR = 6.1; 95% CI, 4.3-28.2). CONCLUSION: Performance of Nd:YAG laser posterior capsulotomy is associated with a significantly elevated risk of retinal detachment in patients who have undergone extracapsular cataract extraction. Other independent risk factors for retinal detachment include axial length, myopia, posterior capsular rupture during surgery, history of retinal detachment or lattice degeneration, and ocular trauma after cataract surgery.

Aged↗

PubMed1987

Permeability of the blood-retinal barrier to carboxyfluorescein in eyes with rhegmatogenous retinal detachment.

Outward and inward permeability of carboxyfluorescein across the blood-retinal barrier were measured fluorophotometrically in seven cynomolgus monkey eyes with experimental rhegmatogenous retinal detachment. Probenecid was used to inhibit outward transport of carboxyfluorescein. The outward permeability was 1.98 +/- 0.31 microliter/min in eyes with retinal detachment and 0.84 +/- 0.15 microliter/min in control eyes with vitrectomy alone (P less than 0.01). The inward permeability, determined separately following intravenous injection, was significantly lower than the outward permeability: 0.14 +/- 0.02 microliter/min for eyes with retinal detachment and 0.04 +/- 0.01 microliter/min for control eyes. Since the outward permeability minus the inward permeability in the presence of probenecid represents that fraction of tracer moving due to fluid flow, it may be concluded that outward flow of fluid across the blood-retinal barrier is a substantial contributor to carboxyfluorescein loss from the vitreous cavity following intravitreal injection.

Animals↗

PubMedDate not supplied

Persistent serous retinal detachment after radial optic neurotomy.

We report the case of a patient presenting with serous retinal detachment following radial optic neurotomy for central retinal vein occlusion. Initially, the retinal detachment was successfully treated by a second vitrectomy and laser coagulation. After reabsorption of the gas tamponade, a recurrence of the retinal detachment was seen with no detectable retinal break. Although other mechanisms should be taken into account, this case indicates that it is possible to create a fistula between the subarachnoid and subretinal space. We conclude from this observation that special attention should be paid to the depth of the radial incision into the optic nerve head.

Aged↗

PubMed2002

Comparison of pre- and post-operational multifocal electroretinograms of retinal detachment.

OBJECTIVES: To explore the changes of multifocal electroretinograms (mfERG) before and after retinal detachment surgery and to evaluate its clinical significance. METHODS: Twenty-three patients (23 eyes) with rhegmatogenous retinal detachment underwent mfERG before and after surgery. The latencies and average response densities of N(1)-wave and P(1)-wave of mfERGs in detached areas, attached areas, fovea and the entire tested area were compared before and after surgery. RESULTS: Preoperatively, the average response densities of N(1)-wave and P(1)-wave in the detached area were significantly smaller than those in attached areas (t = 3.68, t = 4.26, P < 0.01), and the latencies of N(1)-wave and P(1)-wave in detached areas were significantly longer than those in attached areas (t = 3.07, t = 3.89, P < 0.01). Postoperatively, the average response densities of N(1)-wave and P(1)-wave in detached areas, fovea and the entire tested area increased, and there were significant differences pre- and postoperatively (P < 0.05). However, the latencies of N(1)-wave and P(1)-wave before and after surgery showed no significant differences (P > 0.05). CONCLUSIONS: The mfERG is a useful tool to evaluate the recovery of posterior retinal function after retinal detachment surgery. The response density is a more sensitive index than latency to evaluate retinal function of retinal detachment.

Adult↗

PubMed1999

[Serous retinal detachment in preeclampsia].

A 31-year-old woman with severe pre-eclampsia developed bilateral serous retinal detachment on the second day post partum. After a few days there was spontaneous resorption of the subretinal fluid and the visual acuity improved. Ophthalmic examination showed no signs of hypertensive retinopathy. Some changes of the retinal pigment epithelium thought to represent healed infarcts of the choriocapillaris remained. Spontaneous retinal detachment is an uncommon complication of (pre)eclampsia, occurring both ante partum and post partum. Retinal and choroidal vascular damage have been implicated in the pathogenesis. Fluorescein angiographic observations lend support to the hypothesis that retinal detachment is secondary to choroidal vascular damage. The management of retinal detachment as a complication in obstetrics is conservative and the prognosis is good. Retinal detachment in (pre)eclampsia may be an indication for termination of pregnancy.

Adult↗

PubMed1984

[Microsurgery of retinal detachment after perforating injury].

Twenty consecutive retinal detachments (R.D.) after penetrating ocular injury were operated on with vitreoretinal microsurgery. The follow-up after surgery varies from 6 months to 30 months. Retinal reattachment was achieved in 15 of the 20 eyes (75%). The final visual acuity was 0,4 or better in 10 of the 15 eyes operated on with success (66%). Surgical success was achieved in 7 of the 8 R.D. associated with proliferative vitreoretinopathy (P.V.R.) grade C1, C2 and C3; and 6 of the 7 R.D. associated with subretinal proliferation without clinical evidence of epiretinal proliferation. 2 R.D. associated with P.V.R. grade D2 were surgical failures. The patients should be kept under control for a long period of time since gradual shrinkage of the vitreous base may develop beyond 6 months after surgery.

Adolescent↗

PubMed1986

Healon as intravitreal substitute in retinal detachment surgery in 40 patients.

Forty patients with hypotony during retinal detachment surgery were treated with intravitreal Healon. Healon was very well tolerated, except for a transient rise in the intra-ocular pressure in 19 out of 40 patients. A relationship between the rise in intra-ocular pressure and the mount of Healon used was not found. Temporal corneal decompensation occurred in two patients. Early cases of proliferative vitreo-retinopathy with retinal detachment were treated successfully with external retinal-detachment surgery and intravitreal Healon.

Humans↗

PubMed1995

Spontaneous reattachment of retinal detachment with macular hole in nonmyopic patients.

The occurrence of a retinal detachment in a patient with a macular hole is quite rare unless the patient is a high myope or has experienced ocular trauma. The incidence of spontaneous reattachment of retinal detachment with a macular hole is not uncommon in the highly myopic patients. However, data on nonmyopic cases are lacking. I herein describe two nonmyopic cases of retinal detachment with a macular hole, of which retinas reattached spontaneously.

Adult↗