PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Spinal Neoplasms”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 667 records · Page 37Linked to original sources
PubMed1992

[An immunohistochemical and ultrastructural study of 20 chordomas].

Altogether 20 chordomas were reported. The site distribution included 9 cases at the sacrococcygeal region, another 9 cases at the spheno-occipital region, 1 at the cervical vertebra, and another 1 at the lumbar vertebra. Histologic examination revealed that characteristic "physaliphorous cells" were easily identified in all the 19 cases. Tissue for immunohistochemistry study was available in 18 cases. Among them, tumor cells were found strongly positive to EMA, but negative for CEA. 16/18 cases also showed positive for keratin and S-100 protein. Totally, 2 cases were studied ultrastructurally and there were abundant RER and microfilaments seen in the cytoplasm of the tumor cells but only few surface microvilli detected. The epithelial nature of chordoma is strongly supported by the ultrastructural and immunohistochemical findings of these 20 cases.

Adult↗
PubMed1977

Myelography.

Explore the source record for details and available documents.

Back Pain↗
PubMed1992

[Multiple myeloma/plasmacytoma in a young dog].

A multiple myeloma in an unusually young Cairn terrier (13 months, female) is described. Radiographically, pelvic tumor masses and characteristic systemic osteolysis were found at the end of the 4 week disease course. Therapeutic attempts were hopeless at this stage of the disease, but a form of chemotherapy is recommended.

Animals↗
PubMedDate not supplied

Malignant peripheral nerve sheath tumor of the spine after radiation therapy for Hodgkin's lymphoma.

We report the development of a malignant peripheral nerve sheath tumor (MPNST) in 2 patients after irradiation for Hodgkin's lymphoma. Clinicians should be aware of this uncommon, but important fatal complication of radiation therapy. The first case is a 37-year-old man who was diagnosed with nodular sclerosing (NS) Hodgkin's lymphoma and underwent successful mantle radiation. He presented to our neurosurgery service with a left C6 radiculopathy 6 years later. The second case is a 30-year-old female diagnosed with NS Hodgkin's lymphoma. She did well with extensive radiotherapy until 5 years later when she developed severe right arm and chest pain secondary to recurrent lymphoma. After aggressive radio- and chemotherapy, she presented to the neurosurgery service with a right Horner's syndrome, right C6 radiculopathy, and weakness of her right triceps and wrist extensors. Both patients obtained magnetic resonance imaging revealing intradural extramedullary cervical nerve root associated mass lesions. Two years after radiation therapy for his Hodgkin's lymphoma, the first patient underwent a C6 laminectomy at an outside institution for resection of a benign neurofibroma. Four years later, he underwent a posterior C5-7 laminectomy with lateral mass plate fusion and partial excision of a recurrent mass diagnosed as a MPNST. The second patient underwent a C5-6 hemilaminectomy and partial resection of a tumor also pathologically consistent with MPNST. We present 2 case reports of patients who developed neurofibrosarcomatous tumors with malignant transformation after undergoing radiation therapy for Hodgkin's lymphoma. Despite prompt surgical resection, these tumors exhibited aggressive behavior. Numerous cases of soft tissue tumors have been described to arise in areas of prior radiation therapy; however, there have been rare reports of de novo MPNST after radiation therapy, especially in the setting of Hodgkin's lymphoma. Postirradiation MPNST should be considered in the differential diagnosis of a painful, enlarging mass in a previously irradiated area.

Adult↗
PubMed2004

[Transpedicular biopsy of thoracolumbar spine].

INTRODUCTION: Despite advanced diagnostic methods, biopsy of vertebral body remains to be a very important step in treatment of spinal pathologies. Aim of the study was to present experience with mini-open transpedicular biopsy of the vertebral bodies of the thoracolumbar spine in the circumstances of present trend of CT guided needle biopsy preference. MATERIAL AND METHODS: Standard surgical technique was used in obtaining samples in a group of 38 patients during 1996-2001. Indication for biopsy was to identify the etiology of pathological findings on plain films, CT scans or MRI. 21 patients were men and 17 women average age was 59 years (26-76). In 16 cases the biopsy was performed during posterior or combined approach, when spine was stabilized and decompressed, in 22 cases biopsy was done alone from minimal 3-5cm long midline incision, these patients were followed up for 3-6 years. All biopsies were performed in general anesthesia with average duration of 29 minutes. 5 patients were re-biopsied after CT guided needle biopsy performed in another institution, which resulted in inadequate sample collection. Biopsies were performed by 155 mm long trocar with outer diameter of 4.5mm, inner diameter of 3,5mm, providing adequate sample of tissue. RESULTS: The pathology was identified in all cases, second examination of the sample had to be done in one case (97.4%). Average duration of the procedure (29 min) and low radiation exposure (0.1-0.3 min) was reached. DISCUSSION: Although the technique is more invasive than percutaneous, it was not associated with any substantial morbidity, we did not experience any neurological or other complications. As other authors, who deal with spinal neoplasms, we consider the possibility of radical biopsy tract excision during following posterior surgery as very important. CONCLUSION: Based on our results we consider the mini-open fluoroskopic guided transpedicular biopsy with a 3.5-mm inner diameter trocar as safe and effective method of vertebral biopsy. Minimally invasive but still an open approach is advocated to obtain a representative tissue sample.

Adult↗
PubMed2005

Neurological deficit from metastatic low grade liposarcoma.

Myxoid liposarcoma is a malignant soft tissue tumor with a relatively indolent natural history. It commonly occurs in the extremities with extrapulmonary metastatic potential. Round cell liposarcoma, recently, is widely agreed to be the aggressive counterpart of the myxoid liposarcoma, mostly arising in adverse, local recurrence, and metastatic lesions. Metastatic liposarcoma with pure myxoid element is unusual. The authors report an extremely rare case of a 47-year-old Thai male patient having a metastatic pure myxoid liposarcoma to the thoracic vertebrae, one year after primary tumor documented on the left thigh. Histology of the primary and metastatic sites shows only myxoid pattern. Round cell feature was not documented. To the best of the authors' knowledge, this is the second case report of metastatic myxoid liposarcoma without round cell morphology.

Humans↗
PubMed1992

[Encysted gossypiboma of the lesser omentum: complementary aspects of echography and computerized tomography].

The authors report the fortuitous demonstration of an asymptomatic gossypiboma during the preoperative staging of a rectal carcinoma 13 years after abdominal surgery for perforated gastric ulcer. Ultrasonography disclosed a well-defined hypoechoic mass containing highly echogenic foci with a strong posterior shadow. The CT findings are reported, as well as the complementary aspects of sonography. Differential diagnosis from tumors of the lesser omentum is also presented.

Aged↗